Transfusion-Transmissible Infections Monitoring System (TTIMS)

The Food and Drug Administration's Center for Biologics Evaluation and Research is procuring comprehensive services for the Transfusion-Transmissible Infections Monitoring System (TTIMS), which will develop and maintain a surveillance system to monitor transfusion-transmissible infections among U.S. blood donors. The system will focus on tracking HIV, Hepatitis C, Hepatitis B, and Syphilis infections, analyzing data from approximately 60% of the U.S. blood supply across multiple blood centers. Key requirements include collecting and analyzing blood donation data, maintaining a specimen repository, conducting laboratory testing, performing risk factor analyses, and preparing technical reports while ensuring compliance with extensive information security, privacy, and personnel screening requirements. The government will evaluate proposals based on technical capability, past performance, and price, with technical and past performance weighted as relatively more important than price. Proposals are due August 22, 2025, for this solicitation numbered 75F40125Q00337.

This procurement does not utilize any small business set-aside designations and will be awarded as a firm-fixed-price contract structure. The contract includes a base year with three one-year option periods, spanning from September 25, 2025 through September 24, 2029, for a total potential duration of four years. The contractor will be responsible for monitoring transfusion-transmissible infections at participating blood collection organizations and must provide appropriate biohazard containment facilities along with qualified key personnel and subcontractors. Monthly progress reports and semi-annual/annual technical reports containing aggregated infection data will be required deliverables throughout the contract performance period. The work will be performed within the United States, and contractors must demonstrate the capability to execute all tasks and deliverables associated with this specialized monitoring and surveillance system.