Trans-Omics for Precision Medicine (TOPMed) Informatics Research Center (IRC)

The National Heart, Lung and Blood Institute seeks proposals for the Trans-Omics for Precision Medicine Informatics Research Center to process large volumes of genomic and other omics data over the next five years. Proposers must describe procedures for processing whole genome sequencing, RNA-seq, and metabolomics data currently stored in the NHLBI Cloud, as well as plans to enhance pipelines and establish new ones for methylation, proteomics, and single-cell omics data. Proposals will be evaluated based on data processing capabilities, plans to advance tools and technologies, proposed deliverables, and timeline for completion of work. The solicitation will be available on December 18, 2023 through FedConnect, where technical questions may also be submitted until responses are due electronically.

There is no set-aside designated for this procurement. The primary NAICS code is 541380 for research and development in the life sciences with biological research and development services the principal PSC code. The current contractor is the Trans-Omics for Precision Medicine Informatics Research Center, and this pre-solicitation notice seeks a five year renewal of that contract to continue processing the large volumes of genomic and other omics data generated by the TOPMed program and its nine Centralized Omics Resource centers through 2028.