Three photon laser system

Closed Pre-Solicitation Posted

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Solicitation number
75N95024Q00090
Agency
National Institute on Drug Abuse National Institutes of Health, Department of Health and Human Services
Responses due
Set-aside
No set-aside

Opportunity facts

NAICS code
334516 Analytical Laboratory Instrument Manufacturing
PSC
6640 Laboratory Equipment And Supplies

Notice details come from SAM.gov. Updated .

About this opportunity

This notice seeks small business sources for the construction of a three-photon laser system for deep brain imaging at the National Institute of Neurological Disorders and Stroke within the National Institutes of Health. The laser system must meet specific requirements including a compact footprint, maximum repetition rates for the three-photon and integrated pump lasers, wavelength ranges, pulse energies, durations and average powers. Responses to the notice are due by January 2, 2024 and will be used to determine acquisition method and the possibility of a set-aside.

There is no set-aside designated for this requirement. The anticipated NAICS code is 334510 and PSC code is J070. The laser system must be constructed as a single unit with a footprint no larger than 569.0 mm x 320.0 mm x 237.7 mm. The three-photon laser pulse energy must be 500 nJ typical from 1-4 MHz with a minimum of 400 nJ, and the integrated pump laser must produce over 20W of average power at 11 MHz repetition.

Notice text

This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice.

This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition.  It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract.  Responses will not be considered as proposals or quotes.  No award will be made as a result of this notice.  The Government will NOT be responsible for any costs incurred by the respondents to this notice.  This notice is strictly for research and information purposes only.

Background and Objective

A major goal of the research performed by the lab is to understand communication between the neocortex and cerebellum while animals learn novel behavioral skills over weeks. The lab measures activity in both cortex and cerebellum simultaneously using a custom dual-site two-photon microscope, across multiple genetically defined populations using dual-wavelength two-color imaging, and by combining imaging of one neural population with stimulation of another. To build a microscope capable of imaging far deeper structures than accessible to conventional two photon imaging, we must build an imaging system around a laser for three photon absorption imaging.

Project Requirements

The cortex-cerebellum circuitry lab in the National Institute of Neurological Disorders and Stroke (NINDS), within the National Institutes of Health (NIH), requires a three photon laser system for deep brain imaging of red activity reporting fluorophores in learning and behaving animals. The requirement includes:  

One (1) three photon laser with integrated second pump laser, which meets the below salient characteristics:

A. Compact Footprint: The total footprint of the three photon laser head AND integrated pump laser must be no larger than 569.0 mm x 320.0 mm x 237.7 mm (22.40" x 12.60" x 9.36").

B. Three photon laser:
i.  Maximum user-tunable repetition rate of at least 4 MHz
ii. Signal wavelength centered between 1600-1700 nm
iii. 500 nJ typical of pulse energy from 1 – 4 MHz (>400 nJ minimum)
iv. Pulse duration between 50-100 fs

C. Integrated pump laser specifications:
i.  Wavelength must be in the range of 1000-1100 mn
ii. Maximum user-tunable repetition rate of at least 10 MHz
iii. >20 W of time-averaged power at 11 MHz
iv. >3 uJ from 1 - 5 MHz and >2 uJ at maximum repetition rate of 11 MHz
v.  Pulse durations of <250 fs
vi. Integrated motorized dispersion pre-compensation for drive laser

D. Warranty that covers parts and labor for at least 12 months.

Contract Type and Anticipated Delivery Date

The Government anticipates make one (1) Firm, Fixed-Price award. The anticipated delivery date is within 12 weeks After Receipt of Order (ARO).  

Required Information

Companies that believe they possess the capabilities to provide the required products should submit documentation of their ability to meet each of the project requirements to the Contracting Officer. The capability statement must specifically address each of the project requirements separately. Additionally, the capability statement should include any contractor GSA Schedule contracts and/or other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and any other information considered relevant to this program. If subcontracting is anticipated, responses should note the extent of subcontracting anticipated.

Responses must also include:
A. UEI (Unique Entity Identifier)  
B. Organization name
C. Organization address
D. Point of contact
E. Point of contact title, address, telephone, and email address
F. Size and type of business (e.g., 8(a), HUBZone, etc.) pursuant the applicable NAICS code
G. Place of manufacture (i.e. country)

Interested companies are required to identify their type of business, applicable North American Industry Classification System (NAICS) Code, and size standards in accordance with the Small Business Administration. The Government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the notice number.

Submission Instructions and Due Date

Responses must be submitted electronically to Kimberly Espinosa, Contracting Officer, at kimberly.espinosa@nih.gov no later than the date and time listed above.


Disclaimer and Important Notes

This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work.

Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published on SAM.gov. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality

No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).

Notice history

Notices posted for this opportunity, newest first
Notice Type Posted
Three photon laser system Latest solicitation Solicitation
Three photon laser system This notice · Original Pre-Solicitation

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