SOURCES SOUGHT: Purified influenza virus antigens from eggs

Closed Pre-Solicitation Posted

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Solicitation number
75P00125Q00072
Agency
Responses due
Set-aside
No set-aside

Opportunity facts

Place of performance
Bethesda, Maryland, United States

Notice details come from SAM.gov. Updated .

About this opportunity

The Department of Health and Human Services Office of the Assistant Secretary for Administration has issued a sources sought notice for purified influenza virus antigens from eggs to support research conducted by their Structural Informatics Unit. The laboratory requires these purified antigens to design and study the structure and epitope display of influenza vaccine nanoparticles using immunogenicity, biochemical, and electron microscopic techniques. The procurement seeks specific influenza strains including A/PR/8/34, X-31 A/AICHI/68, A/Victoria/3/75, A/HongKong/8/68, and B/Lee, all requiring purified liquid antigens at 2mg/ml concentration stored at -70°C with specific lot numbers and titer requirements. Small business concerns must submit capability statements demonstrating their ability to meet each project requirement to the Contracting Officer. The submission deadline for responses is September 19, 2025, with an anticipated award date of September 24, 2025, and delivery required as soon as possible thereafter.

This opportunity does not include any set-aside designations and is classified under NAICS code 325412 for Pharmaceutical Preparation Manufacturing. The procurement specifies exact quantities needed: 26 units of Influenza A/PR/8/34, 10 units each of X-31 A/AICHI/68 and A/HongKong/8/68, 4 units of A/Victoria/3/75, and 10 units of Influenza B/Lee, along with dry ice and freight services. Each antigen vial contains 1ml of purified liquid antigen, and the specifications include detailed manufacturing dates and titer information for quality control purposes. The notice emphasizes this is strictly a market research activity to identify qualified sources and explicitly states it is not a solicitation for proposals or quotations. No incumbent contractors or budget ranges are mentioned in the documentation provided.

Notice text

This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement.

Project Summary

The laboratory (Structural Informatics Unit) designs and studies the structure and epitopes display of influenza vaccine nanoparticles by immunogenicity, biochemical, and electron microscopic techniques. As such the purified influenza virus will be used to carry out research in vaccine purification, immunogenicity and image processing of electron microscopic images used to study vaccine particle structures assembled from purified influenza virus.

Project requirements:

  1. Influenza A/PR/8/34, Purified 1ml Liquid Purified Antigen at 2mg/ml, Store at -70C Lot:4XP231114 Manufactured Date: 111/14/2023 Titer: EID50=8.4 Additional Titer: HA=4096 (QTY=26)
  2. Influenza X-31 A/AICHI/68, Purified 1ml Liquid Purified Antigen at 2mg/ml, Store at -70C Lot:4XX210323 Titer: HA=65536 Additional Titer: EID50=10.0/ml (QTY=10)
  3. Influenza A/Victoria/3/75, Purified 1ml Liquid Purified Antigen at 2mg/ml, Store at -70C Lot:4XV181116 (QTY=4)
  4. Influenza A/HongKong/8/68, Purified 1ml Liquid Purified Antigen at 2mg/ml, Store at -70C Lot:4XH210305 (QTY=10)
  5. Influenza B/Lee, Purified 1ml Liquid Purified Antigen at 2mg/ml, Store at -70C Lot:4XL180322 Manufactured Date: 3/22/2018 Titer: EID50=8.7 Additional Titer: HA=16384 (QTY=10)
  6. Dry Ice (QTY=1)
  7. Freight Flat Amount (QTY=1)

Anticipated Period of Performance

It is anticipated that an award will be made on or about September 24, 2025. Delivery of equipment will be required as soon as possible.

Capability Statement/Information Sought

Small business concerns that believe they possess the capabilities to provide the required products or services should submit documentation of their ability to meet each of the project requirements to the Contracting Officer. The capability statement must specifically address each of the project requirements separately.  Additionally, the capability statement should include 1) the total number of employees, 2) the professional qualifications of personnel as it relates to the requirements outlined, 3) any contractor GSA Schedule contracts and/or other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Small businesses must also provide their Company Name, DUNS number, Physical Address, and Point of Contact Information.

Interested small businesses are required to identify their type of business, applicable North American Industry Classification System (NAICS) Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number.

The respondent must also provide their DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements.

One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2” x 11” paper size, with 1” top, bottom, left and right margins, and with single or double spacing.

The information submitted must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein.  A cover page and an executive summary may be included but is not required.

The response is limited to ten (10) page limit.  The 10-page limit does not include the cover page, executive summary, or references, if requested.

The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses.

All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer.  Facsimile responses are NOT accepted.

The response must be submitted to Rashiid Cummins, Contract Specialist, at e-mail address Rashiid.Cummins@hhs.gov.

The response must be received on or before September 19, 2025, 10:00 AM, Eastern Time.

Disclaimer and Important Notes

This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality

No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).

Notice history

Notice Type Posted
Purified influenza virus antigens from eggs Latest solicitation Solicitation
This notice Original Pre-Solicitation

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