RNA Sequencing
Closed Solicitation Posted
This opportunity was awarded. See the award notice from .
- Solicitation number
- 1232SA25Q0603
- Agency
- Agricultural Research Service Department of Agriculture
- Responses due
- Set-aside
- Total Small Business
Opportunity facts
- NAICS code
- 541380 Testing Laboratories and Services
- Place of performance
- Geneva, New York 14456, United States
- Points of contact
-
- Elizabeth Wilson elizabeth.wilson2@usda.gov (301) 450-1452
Notice details come from SAM.gov. Updated .
About this opportunity
The United States Department of Agriculture's Agricultural Research Service is soliciting RNA sequencing services through solicitation number 1232SA25Q0603 to conduct comprehensive metabolomic and transcriptomic analysis of grapevine bud tissues. The contractor must provide ultra-sensitive, high-throughput metabolomics and transcriptome sequencing technologies utilizing Ultra Performance Liquid Chromatography and tandem mass spectrometry to detect and quantify over 30,000 plant metabolites, extract RNA, and perform 150 bp paired-end RNA sequencing. The primary objective is to understand grapevine bud responses to winter temperature fluctuations by correlating differentially expressed genes with metabolites to identify traits for improving cold hardiness in grapevines. The procurement will be evaluated on a best value basis considering three factors: price, technical capability (ability to meet or exceed Statement of Work requirements), and past performance. Proposals are due August 22, 2025, with the solicitation having been amended three times since its initial posting on August 9, 2025, including quantity corrections and Statement of Work updates.
This opportunity is designated as a 100% small business set-aside under NAICS code 541380 (Testing Laboratories and Services) with a size standard of $19.0 million in annual receipts. Metware Biotechnology Inc. is specifically named in the Statement of Work as the contractor, suggesting they may be the incumbent or intended awardee. The contract requires processing 54 samples (corrected through Amendment 2 from earlier quantities), with a turnaround time of 6-8 weeks for sample processing and data analysis. Services will be delivered to 630 West North Street, Geneva, NY 14456, though performance will occur at Metware Biotechnology Inc.'s facility in Woburn, Massachusetts. The contract incorporates standard federal acquisition provisions and clauses effective through Federal Acquisition Circular FAC 2025-04, and requires compliance with IT security policies and Section 508 accessibility standards.
Notice text
4 versions
Update #4 · Latest ·
AMENDMENT 3- Posted 8/17/2025- Update to SOW.
AMENDMENT 2- Posted 8/12/2025- Change of Quantity Correction- Should be 54 samples.
AMENDMENT 1- Posted 8/11/2025- Change to Quantity of submitted samples on SOW.
PSC B529–SPECIAL STUDIES/ANALYSIS- SCIENTIFIC DATA
NAICS: 541380 - Testing Laboratories and Services
This is a combined synopsis/solicitation for commercial items/services prepared in accordance with the format in subpart 12.6, utilizing FAR part 13 procedures, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.
(ii) The solicitation number is 1232SA25Q0603 and this combined synopsis/solicitation is issued as a request for quotation (RFQ).
(iii) A statement that the solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular FAC 2025-04, June 11, 2025.
(iv) This is a total 100% small business set-aside and the associated NAICS code is 541380 and the small business size standard is $19.0.
(v) A list of line item number(s) and items, quantities, and units of measure (including option(s), if applicable).
(vi) United States Department of Agriculture (USDA), Agricultural Research Service (ARS) requires a Contractor to provide sequencing services. See attached Statement of Work.
(vii) Place of service/delivery and acceptance: 630 WEST NORTH STREET, GENEVA NY 14456.
(viii) Provision 52.212-1, Instructions to Offerors-Commercial, applies to this acquisition.
(ix) Provision 52.212-2, Evaluation-Commercial Products and Commercial Services is applies to this acquisition. Evaluation will be based on Best Value.
Award will be made on the basis of the best value to the government from quotes meeting or exceeding the acceptability standards for cost and non-cost factors.
Best Value will be evaluated based on the following factors:
- Price
- Technical Capability- Ability to meet or exceed the requirements in the Statement of Work and provide Technical Capability of abilities.
- Past Performance
(x) Offers must have a completed copy of the provision at 52.212-3, Offeror Representations and Certifications-Commercial Products and Commercial Services, uploaded on sam.gov by the time quotes are due.
(xi) The clause at 52.212-4, Contract Terms and Conditions-Commercial Products and Commercial Services, applies to this acquisition.
(xii) The clause at 52.212-5, Contract Terms and Conditions Required To Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. Additional clauses included as attachment: Contract Terms and Conditions
(xiii) In order to be considered for award OFFERORS SHALL SUBMIT ALL OF THE FOLLOWING:
- Submit Firm Fixed Price quotation (quote on company letterhead) detailing the item description, place of manufacture, total price and valid for at least 60 days after receipt of quote, inclusive of all costs.
- Submit Sam.gov Unique Entity ID (UEI) with quotation.
- Submit documentation showing technical capability to meet or exceed Performance Elements in the Statement of Work.
REJECTION OF QUOTATION: Failure to demonstrate compliance or to submit ALL items requested in solicitation will be cause to reject the quote without further discussions.
DISCUSSIONS: The Government intends to award without discussions but reserves the right to conduct discussions should it be deemed in the Government's best interest.
(xv) Quotes are due on 8/22/2025 at 9:00 AM PT by email to Elizabeth Wilson at Elizabeth.Wilson2@usda.gov.
(xvi) Elizabeth Wilson may be reached at Elizabeth.Wilson2@usda.gov for specific questions regarding this combined solicitation. Questions by interested parties regarding the requirement must be submitted by 8/15/2024 by 9:00 AM PT.
Update #3 ·
AMENDMENT 2- Posted 8/12/2025- Change of Quantity Correction- Should be 54 samples.
AMENDMENT 1- Posted 8/11/2025- Change to Quantity of submitted samples on SOW.
PSC B529–SPECIAL STUDIES/ANALYSIS- SCIENTIFIC DATA
NAICS: 541380 - Testing Laboratories and Services
This is a combined synopsis/solicitation for commercial items/services prepared in accordance with the format in subpart 12.6, utilizing FAR part 13 procedures, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.
(ii) The solicitation number is 1232SA25Q0603 and this combined synopsis/solicitation is issued as a request for quotation (RFQ).
(iii) A statement that the solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular FAC 2025-04, June 11, 2025.
(iv) This is a total 100% small business set-aside and the associated NAICS code is 541380 and the small business size standard is $19.0.
(v) A list of line item number(s) and items, quantities, and units of measure (including option(s), if applicable).
(vi) United States Department of Agriculture (USDA), Agricultural Research Service (ARS) requires a Contractor to provide sequencing services. See attached Statement of Work.
(vii) Place of service/delivery and acceptance: 630 WEST NORTH STREET, GENEVA NY 14456.
(viii) Provision 52.212-1, Instructions to Offerors-Commercial, applies to this acquisition.
(ix) Provision 52.212-2, Evaluation-Commercial Products and Commercial Services is applies to this acquisition. Evaluation will be based on Best Value.
Award will be made on the basis of the best value to the government from quotes meeting or exceeding the acceptability standards for cost and non-cost factors.
Best Value will be evaluated based on the following factors:
- Price
- Technical Capability- Ability to meet or exceed the requirements in the Statement of Work and provide Technical Capability of abilities.
- Past Performance
(x) Offers must have a completed copy of the provision at 52.212-3, Offeror Representations and Certifications-Commercial Products and Commercial Services, uploaded on sam.gov by the time quotes are due.
(xi) The clause at 52.212-4, Contract Terms and Conditions-Commercial Products and Commercial Services, applies to this acquisition.
(xii) The clause at 52.212-5, Contract Terms and Conditions Required To Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. Additional clauses included as attachment: Contract Terms and Conditions
(xiii) In order to be considered for award OFFERORS SHALL SUBMIT ALL OF THE FOLLOWING:
- Submit Firm Fixed Price quotation (quote on company letterhead) detailing the item description, place of manufacture, total price and valid for at least 60 days after receipt of quote, inclusive of all costs.
- Submit Sam.gov Unique Entity ID (UEI) with quotation.
- Submit documentation showing technical capability to meet or exceed Performance Elements in the Statement of Work.
REJECTION OF QUOTATION: Failure to demonstrate compliance or to submit ALL items requested in solicitation will be cause to reject the quote without further discussions.
DISCUSSIONS: The Government intends to award without discussions but reserves the right to conduct discussions should it be deemed in the Government's best interest.
(xv) Quotes are due on 8/22/2025 at 9:00 AM PT by email to Elizabeth Wilson at Elizabeth.Wilson2@usda.gov.
(xvi) Elizabeth Wilson may be reached at Elizabeth.Wilson2@usda.gov for specific questions regarding this combined solicitation. Questions by interested parties regarding the requirement must be submitted by 8/15/2024 by 9:00 AM PT.
Update #2 ·
AMENDMENT 1- Posted 8/11/2025- Change to Quantity of submitted samples on SOW.
PSC B529–SPECIAL STUDIES/ANALYSIS- SCIENTIFIC DATA
NAICS: 541380 - Testing Laboratories and Services
This is a combined synopsis/solicitation for commercial items/services prepared in accordance with the format in subpart 12.6, utilizing FAR part 13 procedures, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.
(ii) The solicitation number is 1232SA25Q0603 and this combined synopsis/solicitation is issued as a request for quotation (RFQ).
(iii) A statement that the solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular FAC 2025-04, June 11, 2025.
(iv) This is a total 100% small business set-aside and the associated NAICS code is 541380 and the small business size standard is $19.0.
(v) A list of line item number(s) and items, quantities, and units of measure (including option(s), if applicable).
(vi) United States Department of Agriculture (USDA), Agricultural Research Service (ARS) requires a Contractor to provide sequencing services. See attached Statement of Work.
(vii) Place of service/delivery and acceptance: 630 WEST NORTH STREET, GENEVA NY 14456.
(viii) Provision 52.212-1, Instructions to Offerors-Commercial, applies to this acquisition.
(ix) Provision 52.212-2, Evaluation-Commercial Products and Commercial Services is applies to this acquisition. Evaluation will be based on Best Value.
Award will be made on the basis of the best value to the government from quotes meeting or exceeding the acceptability standards for cost and non-cost factors.
Best Value will be evaluated based on the following factors:
- Price
- Technical Capability- Ability to meet or exceed the requirements in the Statement of Work and provide Technical Capability of abilities.
- Past Performance
(x) Offers must have a completed copy of the provision at 52.212-3, Offeror Representations and Certifications-Commercial Products and Commercial Services, uploaded on sam.gov by the time quotes are due.
(xi) The clause at 52.212-4, Contract Terms and Conditions-Commercial Products and Commercial Services, applies to this acquisition.
(xii) The clause at 52.212-5, Contract Terms and Conditions Required To Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. Additional clauses included as attachment: Contract Terms and Conditions
(xiii) In order to be considered for award OFFERORS SHALL SUBMIT ALL OF THE FOLLOWING:
- Submit Firm Fixed Price quotation (quote on company letterhead) detailing the item description, place of manufacture, total price and valid for at least 60 days after receipt of quote, inclusive of all costs.
- Submit Sam.gov Unique Entity ID (UEI) with quotation.
- Submit documentation showing technical capability to meet or exceed Performance Elements in the Statement of Work.
REJECTION OF QUOTATION: Failure to demonstrate compliance or to submit ALL items requested in solicitation will be cause to reject the quote without further discussions.
DISCUSSIONS: The Government intends to award without discussions but reserves the right to conduct discussions should it be deemed in the Government's best interest.
(xv) Quotes are due on 8/22/2025 at 9:00 AM PT by email to Elizabeth Wilson at Elizabeth.Wilson2@usda.gov.
(xvi) Elizabeth Wilson may be reached at Elizabeth.Wilson2@usda.gov for specific questions regarding this combined solicitation. Questions by interested parties regarding the requirement must be submitted by 8/15/2024 by 9:00 AM PT.
Update #1 ·
PSC B529–SPECIAL STUDIES/ANALYSIS- SCIENTIFIC DATA
NAICS: 541380 - Testing Laboratories and Services
This is a combined synopsis/solicitation for commercial items/services prepared in accordance with the format in subpart 12.6, utilizing FAR part 13 procedures, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.
(ii) The solicitation number is 1232SA25Q0603 and this combined synopsis/solicitation is issued as a request for quotation (RFQ).
(iii) A statement that the solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular FAC 2025-04, June 11, 2025.
(iv) This is a total 100% small business set-aside and the associated NAICS code is 541380 and the small business size standard is $19.0.
(v) A list of line item number(s) and items, quantities, and units of measure (including option(s), if applicable).
(vi) United States Department of Agriculture (USDA), Agricultural Research Service (ARS) requires a Contractor to provide sequencing services. See attached Statement of Work.
(vii) Place of service/delivery and acceptance: 630 WEST NORTH STREET, GENEVA NY 14456.
(viii) Provision 52.212-1, Instructions to Offerors-Commercial, applies to this acquisition.
(ix) Provision 52.212-2, Evaluation-Commercial Products and Commercial Services is applies to this acquisition. Evaluation will be based on Best Value.
Award will be made on the basis of the best value to the government from quotes meeting or exceeding the acceptability standards for cost and non-cost factors.
Best Value will be evaluated based on the following factors:
- Price
- Technical Capability- Ability to meet or exceed the requirements in the Statement of Work and provide Technical Capability of abilities.
- Past Performance
(x) Offers must have a completed copy of the provision at 52.212-3, Offeror Representations and Certifications-Commercial Products and Commercial Services, uploaded on sam.gov by the time quotes are due.
(xi) The clause at 52.212-4, Contract Terms and Conditions-Commercial Products and Commercial Services, applies to this acquisition.
(xii) The clause at 52.212-5, Contract Terms and Conditions Required To Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. Additional clauses included as attachment: Contract Terms and Conditions
(xiii) In order to be considered for award OFFERORS SHALL SUBMIT ALL OF THE FOLLOWING:
- Submit Firm Fixed Price quotation (quote on company letterhead) detailing the item description, place of manufacture, total price and valid for at least 60 days after receipt of quote, inclusive of all costs.
- Submit Sam.gov Unique Entity ID (UEI) with quotation.
- Submit documentation showing technical capability to meet or exceed Performance Elements in the Statement of Work.
REJECTION OF QUOTATION: Failure to demonstrate compliance or to submit ALL items requested in solicitation will be cause to reject the quote without further discussions.
DISCUSSIONS: The Government intends to award without discussions but reserves the right to conduct discussions should it be deemed in the Government's best interest.
(xv) Quotes are due on 8/22/2025 at 9:00 AM PT by email to Elizabeth Wilson at Elizabeth.Wilson2@usda.gov.
(xvi) Elizabeth Wilson may be reached at Elizabeth.Wilson2@usda.gov for specific questions regarding this combined solicitation. Questions by interested parties regarding the requirement must be submitted by 8/15/2024 by 9:00 AM PT.
Attachments
| File | Type | Posted |
|---|---|---|
| Statement of Work v3.docx | DOCX document | |
| Statement of Work.docx | DOCX document | |
| Statement of Work v2.docx | DOCX document | |
| Statement of Work.docx | DOCX document | |
| Contract Terms and Conditions.docx | DOCX document | |
| Wage Determination 2015-4161 Rev. 31 07082025.pdf |
Notice history
| Notice | Type | Posted |
|---|---|---|
| RNA Sequencing | Award Notice | |
| RNA Sequencing | Solicitation |
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