ReVector

The Defense Advanced Research Projects Agency seeks proposals to develop methods for modulating human skin microbiomes through its ReVector program. The goal is to engineer skin microbiomes using advanced data analytics and modulation tools in order to alter personal chemical signatures and reduce mosquito attraction and disease transmission risks for military personnel. Proposals are due by July 11, 2019 and must include plans to identify microbiome-based metabolites that attract mosquitoes, design interventions to lessen attraction and feeding, and establish reliable and safe microbiome manipulation techniques. Evaluation will be based on the stated objectives, technical approach, and ability to complete defined tasks on schedule over multiple phases of performance.

The opportunity has no set-aside designations. The primary NAICS code is 541715 and PSC code R425 covers research and development in the biological sciences. Multiple awards are anticipated over four years involving in vitro and animal model studies during an initial 18-month base period and two subsequent 18-month and 12-month option periods to test tools and conduct potential human/non-human primate research. Detailed budgets using the provided templates are required from all prime contractors and subcontractors seeking participation. Indirect rates and labor categories must be disclosed along with itemized costs for personnel, travel, materials, equipment and other expenses.