Research and Development: Protein Kinetic Response to Calorie Deprivation for the US Army Research Institute of Environmental Medicine (USARIEM)
Closed Special Notice Posted
A later notice was posted: the Limited / Sole Source Justification from .
- Solicitation number
- W81XWH21R0012
- Agency
-
Medical Command
Department of the Army, Department of Defense
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Place of performance
- Natick MA 01760 USA
Notice details come from SAM.gov. Updated .
About this opportunity
This Special Notice from the United States Army Medical Research Acquisition Activity intends to negotiate on a sole source basis with the University Of Arkansas For Medical Sciences for research and development services. The Military Nutrition Division within the U.S. Army Research Institute of Environmental Medicine requires determination of whole-body and muscle protein kinetic responses to high quality protein intake during graded levels of calorie deficiency.
The purpose of this effort is to understand the effects of graded calorie deficit on whole-body and muscle protein kinetics in order to devise optimized dietary strategies that overcome catabolic effects of calorie deficit during sustained military operations. Key deadlines include a due date of January 15, 2021 for the University Of Arkansas to provide development and execution of a clinical research trial assessing protein turnover and muscle protein synthesis responses to protein intake under calorie deficits in young adults. This requires procurement of stable isotopes and biological sample analyses. Insights will inform Army nutrition standards and combat ration development to support soldier performance in future multi-domain operations.
Notice text
The United States Army Medical Research Acquisition Activity (USAMRAA) intends to negotiate on a sole source basis, IAW FAR 6.302-1(a), with the University Of Arkansas For Medical Sciences located at 4301 W Markham St, Ste. 525 Little Rock, AR, 72205-7101 as the only responsible source that can provide The Military Nutrition Division (MND) within the U.S. Army Research Institute of Environmental Medicine (USARIEM) development and execution of a clinical research trial assessing the effects of graded calorie deficits on whole-body protein turnover and muscle protein synthesis responses to high-quality protein intake in young adults. Below outlines the specifics of the Research and Development efforts.
USARIEM has a need to determine whole-body and muscle protein kinetic responses to high quality protein intake during graded levels of calorie deficiency. Calorie deficiency and its catabolic effects on whole-body protein status and muscle mass is open unavoidable when subsisting primarily on combat rations during sustained military operations in austere environments. Understanding the effects of graded calorie deficit on whole-body and muscle protein kinetics is critical for USARIEM to devise and test optimized dietary strategies that overcome the catabolic effects of calorie deficit. The knowledge gained from this effort will inform Army Regulation 40-25 (Nutrition and Menu Standards for Human Performance Optimization) and the U.S. Army Combat Capabilities Development Command Soldier Center, Combat Feeding Directorate in their efforts to develop and optimize next generation combat rations for use in future Multi-Domain Operations. This Research and Development (R&D) effort will require the procurement of stable isotopes and biological sample (blood and muscle) analyses to calculate whole-body protein turnover, muscle protein synthesis, and essential amino acid concentrations.
Notice history
| Notice | Type | Posted |
|---|---|---|
| Research and Development: Protein Kinetic Response to Calorie Deprivation for the US Army Research Institute of Environmental Medicine (USARIEM) | Limited / Sole Source Justification | |
| This notice | Special Notice | |
| Research and Development: Protein Kinetic Response to Calorie Deprivation for the US Army Research Institute of Environmental Medicine (USARIEM) | Pre-Solicitation |
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