Reconstructed human small intestine and pigmented epidermis microtissue samples and culture media

The Food and Drug Administration's National Center for Toxicological Research is procuring reconstructed human small intestine and pigmented epidermis microtissue samples along with associated culture media for research purposes. The solicitation requires 144 reconstructed human small intestine tissue samples with maintenance media and 144 reconstructed human pigmented epidermis samples with maintenance media, both meeting specific technical specifications including air-liquid interface culturing methods. The small intestine tissues must contain epithelial, endothelial, and fibroblast cells derived from human donors, while the pigmented epidermis samples must feature human keratinocytes and melanocytes from both Caucasian/White and African American/Black donors. This Combined Synopsis/Solicitation operates under NAICS code 541715 for Research and Development in Physical, Engineering, and Life Sciences. Proposals are due by June 18, 2025 at 3:00 PM Central Time, and the contract will be awarded as a firm-fixed-price commercial product arrangement.

This procurement is designated as a total small business set-aside, restricting competition to qualified small businesses under the applicable size standards. The contract will involve multiple delivery shipments scheduled between June and September 2025, with all samples requiring FedEx priority overnight shipping to the NCTR facility in Jefferson, Arkansas. The solicitation does not specify contract value ranges, but pricing must include all shipping costs and contractors will be required to submit invoices electronically through the Invoice Processing Platform. No incumbent contractors or potential award values are identified in the solicitation documentation. Performance will involve the production and delivery of highly specialized biological research materials that meet stringent technical requirements for FDA toxicological research applications.