Preclinical Pharmacokinetic and Pharmacology Evaluations of Agents Being Developed for Cancer Patients

OFFICE OF ACQUISITIONS
NATIONAL CANCER INSTITUTE

REQUEST FOR PROPOSAL NUMBER: 75N91021R00007

Amendment No.: 3

Date of Issuance: 1/11/2021

The above numbered Request For Proposal (RFP) is amended as set forth below. The hour and date specified for receipt of Offerors is unchanged.

Offerors MUST acknowledge receipt of the amendment prior to the hour and the date specified in the solicitation or as amended, by separate letter, telegram, or Electronic Mail which includes a reference to the RFP and Amendment number(s). For your convenience, the Proposal Intent Response Form is provided in SECTION J - List of Attachments of this RFP, for this purpose.

FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERORS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER.

This Amendment responds to a question received related to this RFP:

Question 1

Do contractors need to respond to all of the sample task orders when these are not within the capabilities?

Answer 1

See SECTION L – INSTRUCTIONS, CONDITIONS, AND NOTICES TO OFFERORS (2)(a)(2)(II.) TECHNICAL PROPOSAL; which states, “PLEASE PROVIDE A RESPONSE TO THE STATEMENT OF WORK FOR THE PK IDIQ BASE CONTRACT (SHOWN AS ATTACHMENT 3 IN SECTION J). PLEASE ALSO PROVVIDE A RESPONSE TO TASK ORDER #1 AND ALL SAMPLE TASK ORDERS (SHOWN AS ATTACHMENT 4 – 8, IN SECTION J).  

It is required that each contractor respond to Attachments 3 through Attachment 8 under this RFP.

Amendment No.: 2 for RFP No. 75N91021R00007

Date of Issuance: 1/4/2021

The above numbered Request For Proposal (RFP) is amended as set forth below. The hour and date specified for receipt of Offerors is unchanged.

Offerors MUST acknowledge receipt of the amendment prior to the hour and the date specified in the solicitation or as amended, by separate letter, telegram, or Electronic Mail which includes a reference to the RFP and Amendment number(s). For your convenience, the Proposal Intent Response Form is provided in SECTION J - List of Attachments of this RFP, for this purpose.

FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERORS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER.

This Amendment revises the RFP as stated below:

SECTION L – INSTRUCTIONS, CONDITIONS, AND NOTICES TO OFFERORS subparagraph (2)(a) GENERAL INSTRUCTIONS hereby adds the below language:

The following instructions will establish the acceptable minimum requirements for the format and contents of proposals. Special attention is directed to the requirements for technical and business proposals to be submitted in accordance with these instructions. “Each proposal will be reviewed for compliance with Section L. Instructions, Conditions and Notices to Offerors, of the solicitation. The Technical Proposal must contain the documents set forth in Section L.2.a.2.II, Authorized Official and Submission of Proposal, TECHNICAL PROPOSAL.  Any proposal submission that fails to meet these requirements will be evaluated as noncompliant and eliminated from further review.”

SECTION L – INSTRUCTIONS, CONDITIONS, AND NOTICES TO OFFERORS subparagraph (2)(a)(11) Selection of Offerors is hereby revised the below language:

“The acceptability of the scientific and technical portion of each compliant contract proposal will be evaluated by a technical review committee.”

THE REMAINDER OF THESE SECTIONS REMAINS UNCHANGED.

Amendment No.: 1 for RFP No. 75N91021R00007

Date of Issuance: 12/16/2020

The above numbered Request For Proposal (RFP) is amended as set forth below. The hour and date specified for receipt of Offerors is changed to: January 15, 2021 at 4:00 PM ET. 

Offerors MUST acknowledge receipt of the amendment prior to the hour and the date specified in the solicitation or as amended, by separate letter, telegram, or Electronic Mail which includes a reference to the RFP and Amendment number(s). For your convenience, the Proposal Intent Response Form is provided in SECTION J - List of Attachments of this RFP, for this purpose.

FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERORS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. 

THIS AMENDMENT HEREBY EXTENDS THE DEADLINE FOR RECEIPT OF QUESTIONS TO JANUARY 6, 2021 AT 4:00 PM ET AND EXTENDS THE RECEIPT OF PROPOSALS DUE DATE AND TIME TO JANUARY 15, 2021 AT 4:00 PM ET.  Please follow the instructions in Attachment 1, “eCPS Proposal Delivery Instructions” for submitting your proposals by the revised due date and time (January 15, 2021 4:00 PM ET). 

This Amendment also answers questions related to RFP 75N91021R00007, please carefully review the 75N91021R00007 Amend 1 document. 

Please see attached Request For Proposal (RFP) No. 75N91021R00007, for the "Preclinical Pharmacokinetic and Pharmacology Evaluations of Agents Being Developed for Cancer Patients," and reference all attachments. 

Proposals for furnishing the supplies and/or services in THE SCHEDULE (see attached) will be received at the place specified in, and in the number of copies specified in Attachment 1, "eCPS Proposal Delivery Instructions," until 4:00 PM ET on January 4, 2021. Offers will be valid for 120 days unless a different period is specified by the offeror on the Attachment entitled, "Proposal Summary and Data Record, NIH 2043. The deadline for receipt of questions is December 18, 2020 at 4:00 PM ET per the instructions in Section L.1 General Instructions (see attached RFP). 

Offerors are asked to return the proposal intent form (Attachment 2) by December, 18, 2020 (via eCPS website) if they intend to submit a response to this RFP.  Submit all questions in writing to the Contracting Officer via email at alexis.hudak@nih.gov.