Notice of Intent to Sole Source - Custom Commercial Aptamer Procurement
Closed Special Notice Posted
- Solicitation number
- PANAPG-26-P-0000-051608
- Agency
-
Department of the Army
Department of Defense
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Place of performance
- Maryland 21010, United States
Notice details come from SAM.gov. Updated .
About this opportunity
The U.S. Army Contracting Command - Aberdeen Proving Ground (ACC-APG), Edgewood Division announced on August 19, 2026 a notice of intent to award a sole-source contract to Aptagen, LLC for custom synthesis, purification, quality control, and delivery of DNA, RNA, and peptide aptamers supporting U.S. Army Combat Capabilities Development Command Chemical Biological Center diagnostic assay development, biosensor research, and chemical/biological defense platforms. The Army considers Aptagen the only vendor capable of meeting the technical requirement: aptamers must undergo denaturing Polyacrylamide Gel Electrophoresis (dPAGE) purification; standard HPLC or cartridge purification is unacceptable. Deliveries must include Double-Tier Empirical Quality Control using both ElectroSpray Ionization Mass Spectrometry and 10% Urea Gel dPAGE sequence-verification analysis. The award will be Firm Fixed Price under FAR 6.103-1 (Revolutionary Federal Acquisition Regulation Overhaul). Though not a request for competitive quotations, any responses demonstrating capability to provide equivalent aptamers will be reviewed if submitted to Contract Specialist Sammy Solo and Contracting Officer Nicholas Granata Jr. by September 1, 2026, 12:00 pm EST — seven days from notice issuance. Aptagen is located in Jacobus, Pennsylvania (CAGE Code 436H7).
Notice text
2 versions
Update #2 · Latest ·
The U.S. Army Contracting Command – Aberdeen Proving Ground (ACC-APG), Edgewood Division intends to issue a Firm Fixed Price award on a sole source basis in accordance with Revolutionary Federal Acquisition Regulation Overhaul (RFO) FAR 6.103-1 to support the U.S. Army Combat Capabilities Development Command Chemical Biological Center (DEVCOM CBC) and their requirement for a mission-critical, continuing requirement for the custom synthesis, purification, quality control, and delivery of deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and peptide aptamers, with or without chemical modifications delivered in lyophilized form. These aptamers serve as foundational biological recognition elements in diagnostic assay development, biosensor research, and chemical/biological defense mission-support platforms.
The synthesized aptamers will undergo denaturing Polyacrylamide Gel Electrophoresis (dPAGE) purification. Standard commercial HPLC or cartridge purification is technically unacceptable.
The vendor will provide empirical sequence-verification data using both ElectroSpray Ionization (ESI) Mass Spectrometry and 10% Urea Gel dPAGE analysis with every delivery order (Double-Tier Empirical Quality Control).
The intent is to award this contract to Aptagen, LLC., CAGE Code 436H7. Aptagen LLC. is located at 250 North Main Street, Jacobus, PA 17407. At this time, it is the Government’s understanding that no other contractor is capable of supplying the required aptamers.
This notice of intent is not a request for competitive quotations; however, all responses received within seven (7) days of the issuance of this notice will be reviewed accordingly by the Government. Any response should be emailed to Contract Specialist, Sammy Solo at sammy.b.solo.civ@army.mil and Contracting Officer, Nicholas Granata Jr. at nicholas.granata.civ@army.mil by 12:00 pm EST on 01 September 2026.
Update #1 ·
The U.S. Army Contracting Command – Aberdeen Proving Ground (ACC-APG), Edgewood Division intends to issue a Firm Fixed Price award on a sole source basis in accordance with Revolutionary Federal Acquisition Regulation Overhaul (RFO) FAR 6.103-1 to support the U.S. Army Combat Capabilities Development Command Chemical Biological Center (DEVCOM CBC) and their requirement for a mission-critical, continuing requirement for the custom synthesis, purification, quality control, and delivery of deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and peptide aptamers, with or without chemical modifications delivered in lyophilized form. These aptamers serve as foundational biological recognition elements in diagnostic assay development, biosensor research, and chemical/biological defense mission-support platforms.
The synthesized aptamers will undergo denaturing Polyacrylamide Gel Electrophoresis (dPAGE) purification. Standard commercial HPLC or cartridge purification is technically unacceptable.
The vendor will provide empirical sequence-verification data using both ElectroSpray Ionization (ESI) Mass Spectrometry and 10% Urea Gel dPAGE analysis with every delivery order (Double-Tier Empirical Quality Control).
The intent is to award this contract to Aptagen, LLC., CAGE Code 436H7. Aptagen LLC. is located at 250 North Main Street, Jacobus, PA 17407. At this time, it is the Government’s understanding that no other contractor is capable of supplying the required aptamers.
This notice of intent is not a request for competitive quotations; however, all responses received within seven (7) days of the issuance of this notice will be reviewed accordingly by the Government. Any response should be emailed to Contract Specialist, Sammy Solo at sammy.b.solo.civ@army.mil and Contracting Officer, Nicholas Granata Jr. at nicholas.granata.civ@army.mil by 3:00 pm EST on 26 August 2026.
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