NINDS BPN Preclinical Testing and Toxicology Program

Award Notice Posted

Solicitation number
A75N98026R00138
Agency
Awarded
to Sri International
Set-aside
No set-aside

Opportunity facts

Contract number
HHSN271201600006I Federal IDV award
NAICS code
Not on record
PSC
Not on record

Notice details come from SAM.gov. Updated .

About this opportunity

The National Institute of Neurological Disorders and Stroke (NINDS), under the National Institutes of Health, extended the ordering period on four existing IDIQ contracts for the Blueprint Neurotherapeutics Network (BPN) Preclinical Testing and Toxicology Program (PTTP) through September 12, 2027—a one-year extension effective September 13, 2026—with no cost to the government and no changes to contract terms, conditions, scope, or ceiling values.

The four incumbent contractors are SRI International, Southern Research, IIT Research Institute (IITRI), and University of Illinois Chicago Toxicology Research Laboratory (TRL). Each contract holds a maximum value of $174.47 million; $147.04 million remains available for task orders across both performance areas: Management and Operations Support and Pharmacology and Toxicology Studies. Services include analytical method development, in vivo and in vitro pharmacokinetic studies, preclinical acute and chronic toxicity evaluations, safety pharmacology studies, genotoxicity and carcinogenicity assessments, and ADMET assays.

The extension was made under unusual and compelling urgency authority (41 U.S.C. 3304(a)(2)) because these four contractors are the sole current PTTP IDIQ holders with GLP-IND-enabling capabilities and validated protocols. Transitioning work to new contractors would risk approximately $9–10 million in grant investments and cause GLP toxicology test article batches to expire before use. A follow-on competitive procurement is anticipated to award in August/September 2027 following solicitation release in December 2026.

Notice text

NINDS Blueprint Neurotherapeutics Network (BPN) extended the ordering period of four (4) existing Indefinite Delivery, Indefinite Quantity (IDIQ) contracts awarded under the BPN Preclinical Testing and Toxicology Program (PTTP), with the contractors listed below. This action extends the ordering period by one year, from September 13, 2026, through September 12, 2027. This is a no-cost modification; no other changes to the contracts' terms, conditions, scope, or ceiling value are being made.

SRI International      

HHSN271201600006I

Southern Research 

HHSN271201600007I            

IIT Research Institute (IITRI)

75N95021D00026

University of Illinois Chicago, Toxicology Research Laboratory (TRL)             

75N95022D00026

Please refer to the attached justification for additional information.

Awarded contract HHSN271201600006I to SRI INTERNATIONAL for 0.00 on 2026-09-12.

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