Mouse head-fixation with locomotor navigation system (brand name or equal)

Closed Pre-Solicitation Posted

Solicitation number
75N95025Q00199SB
Agency
Responses due
Set-aside
Total Small Business

Opportunity facts

Place of performance
Baltimore, Maryland 21224, United States

Notice details come from SAM.gov. Updated .

About this opportunity

The National Institute on Drug Abuse (NIDA), part of the Department of Health and Human Services, is conducting market research for a mouse head-fixation with locomotor navigation system through this Small Business Sources Sought notice. The agency requires a behavioral device that enables simultaneous measurement of conditioned behavioral responses and neural activities from the same mouse subject during two-photon calcium-imaging recordings. The system must allow mice to produce behavioral responses while being head-fixed, supporting NIDA's behavioral experiments that record calcium signals indicating neuronal activity from mouse brains. This notice seeks information about qualified small business sources' availability, capability, size classification under NAICS code 334516 (Analytical Laboratory Instrument Manufacturing), and the availability of domestic manufacturing sources. Responses to this market research notice are due by July 7, 2025, and interested parties must address manufacturing location and compliance with Non-Manufacturer Rule requirements.

This opportunity is designated as a Total Small Business set-aside, restricting participation to qualifying small businesses under the applicable NAICS code. The government is specifically seeking information about various small business categories including HUBZone, service-disabled veteran-owned, 8(a), veteran-owned, woman-owned, and small disadvantaged businesses. No incumbent contractors or specific award values are mentioned in this pre-solicitation notice, as this is strictly a market research effort to determine acquisition methodology. The notice emphasizes that this is not a solicitation for proposals or quotes, no awards will be made based on responses, and the government will not reimburse any costs incurred by respondents. The procurement falls under PSC code 6640 for Laboratory Equipment and Supplies, and responses must include detailed information about manufacturing locations to support Buy American Act compliance considerations.

Notice text

This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations.
The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition; and (4) availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of a satisfactory quality.
For equipment/supply requirements, responses must include the place of manufacturing (i.e. address if supply/equipment is a domestic end product and include country of manufacture). For equipment/supply requirements, small businesses must also address the size status of the manufacturer under the applicable NAICS code (i.e. address Non-Manufacturer Rule).
Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice.
This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only.

This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement.
This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement, to determine the method of acquisition, and availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of a satisfactory quality. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Small businesses are encouraged to respond.

The Mobile HomeCage allows the National Institute on Drug Abuse (NIDA) to conduct behavioral experiments while calcium signals, indicating neuronal activities, from the mouse brain are being recorded. To understand behavioral functions of neural activity, NIDA requires a behavioral device that fulfills two major needs. First, it is necessary to measure conditioned (operant and Pavlovian) behavioral responses and neural activities from the same subject at the same time. Second, the mouse must be able to produce behavioral responses while being head-fixed for the two-photon calcium-imaging recording.
Generic Product Name: Mouse head-fixation with locomotor navigation system

Files

File Type Posted
SBSSN_Buy American - SAM.pdf PDF

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