Metagenomics Analysis

The FDA Office of Acquisition and Grant Services is seeking a webservice subscription for comprehensive metagenomics analysis services to support critical evaluation of human and animal food safety. The procurement, designated as RFQ No. 75F40125Q00340, requires bioinformatic analysis of metagenomic data with specific focus on characterizing antimicrobial resistance (AMR), taxonomic classifications, and functional features of food environments. Key technical requirements include Microbiome Multivariate Association with Linear Models (MaAsLin2 and MaAsLin3) analysis, MetaCyc functional pathway annotation for over 300 datasets, enzyme classification, and Linear discriminate analysis Effect Size (Lefse analysis). The government will evaluate quotes based on submission of all schedule items and verification that the quoter is an authorized distributor/reseller or manufacturer/provider of the required services. The contract will be awarded to the responsible quoter submitting the lowest-priced technically acceptable quote that meets all solicitation requirements. Quotes must be submitted through SAM by September 23, 2025, at 5:00 PM EST.

This opportunity does not utilize any set-aside designation and is open to all eligible contractors. The solicitation does not identify any incumbent contractors or potential award values within the available documentation. The contract structure is a Firm Fixed Price task order with a twelve-month base period of performance. Technical support requirements include provision of virtual meetings and issue resolution within 48 hours of reported problems. Performance will occur at the contractor's site rather than at government facilities. The place of performance is designated as Rockville, Maryland, which aligns with the FDA's operational headquarters location.