Long Sequencing Kits

Closed Pre-Solicitation Posted

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Solicitation number
75N95025Q00095
Agency
Responses due
Set-aside
No set-aside

Opportunity facts

Place of performance
Bethesda, Maryland 20892, United States

Notice details come from SAM.gov. Updated .

About this opportunity

The National Institutes of Health (NIH), specifically the National Institute on Drug Abuse, is seeking to procure Long Sequencing Kits for biomarker research related to Alzheimer's disease. The procurement involves acquiring 25 flow cells compatible with Nanopore PromethION 48 sequencers that can generate up to 290 Gb for sequencing DNA, cDNA, or native RNA in real-time. This is currently a small business sources sought notice designed to identify qualified small business contractors who can meet technical specifications, including flow cells with Application-Specific Integrated Circuit (ASIC) and recyclable electrical components. Potential respondents must submit a capability statement electronically to Contract Specialist Andrea Clay by December 31, 2024, at 12:00 PM Eastern Time. The response must be limited to ten pages and directly address each project requirement, including company details such as DUNS number, business type, and contact information.

This pre-solicitation notice is not a committed solicitation but a market research effort to determine potential small business sources. While no specific set-aside has been definitively established, the government is specifically seeking responses from small business categories including HUBZone, service-disabled veteran-owned, 8(a), veteran-owned, woman-owned, and small disadvantaged businesses. The contract performance will be located at 9000 Rockville Pike, Bethesda, MD, with an initial delivery timeline of 12 months and two potential 12-month option periods. No specific budget range or award value is mentioned in the notice. Respondents are advised that this notice does not guarantee a contract award and that the government reserves the right to use submitted information for developing future solicitation requirements. Importantly, no proprietary, classified, confidential, or sensitive information should be included in the response.

Notice text


•    Solicitation Number: 75N95025Q00095
•    Title: Long Sequencing Kits 

•    NAICS Code:  325413 In Vitro Diagnostic Substance Manufacturing

•     Description:  

This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice.

This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition.  It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract.  Responses will not be considered as proposals or quotes.  No award will be made as a result of this notice.  The Government will NOT be responsible for any costs incurred by the respondents to this notice.  This notice is strictly for research and information purposes only.

Background:  

Biomarkers play a critical role in understanding, diagnosing, and monitoring disease progression and therapeutic efficacy. We aim to perform long read sequencing to analyze several biomarkers that will provide information about underlying molecular changes associated with AD/ADRD in well characterized samples from patients.

1.    Purpose and Objectives: The purpose of this acquisition is to purchase Long Sequencing kits.  


Description: 

The Contractor shall provide the Government with the following: 

The flow cell must be able to generate up to 290 Gb for sequencing DNA, cDNA or native RNA in real-time. 

The flow cell must be compatible with Nanopore PromethION 48 sequencers in form, fit, and function

The flow cell must contain Application-Specific Integrated Circuit (ASIC) to control and measure sequencing process

The flow cell must contain recyclable electrical components. 


4.    Quantity: 25 each

5.    Delivery Date: 12 months w/2 (two) 12 twelve month option periods


Place of Performance:
9000 Rockville Pike
Bethesda, MD 20892

Capability statement /information sought. Contractors that believe they possess the ability to provide the requirement should submit documentation of their ability to meet each of the project requirements to the Contract Specialist. The response should directly and specifically state in the, capabilities statement, which project requirements you can supply. Contractors must also provide their Company Name, DUNS Number, Physical Address, Point of Contact, and Size and Type of Business (e.g., 8(a), HubZone, etc.) pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements.

One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2” x 11” paper size, with 1” top, bottom, left and right margins, and with single or double spacing.

The information submitted must be must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein.  A cover page and an executive summary may be included but is not required. 

The response is limited to ten (10) page limit.  The 10-page limit does not include the cover page, executive summary, or references, if requested.

The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses.

All responses (capability statements) sent in response to this Small Business Sources Sought Notice must be submitted electronically (via e-mail) to the Contract Specialist. Facsimile responses are NOT accepted.

The response must be submitted to Andrea Clay, Contract Specialist at e-mail address amcgee@mail.nih.gov 

The response must be received on or before December 31, 2024 at 12:00PM, eastern time.

 “Disclaimer and Important Notes:  This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work. 

Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).”
 

Notice history

Notice Type Posted
Long Read Sequencing Kits Latest solicitation Solicitation
This notice Original Pre-Solicitation

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