Large-scale T cell immune epitope discovery and mechanisms of T cell protection

Closed Solicitation Posted

This opportunity was awarded. See its 5 award notices in the notice history.

Solicitation number
BAA-NIAID-DAIT-75N93022R00023
Agency
Responses due
Set-aside
No set-aside

Opportunity facts

Notice details come from SAM.gov. Updated .

About this opportunity

The Department of Health and Human Services National Institutes of Health (NIH) is seeking proposals for a multi-disciplinary research program focused on large-scale discovery and validation of T cell immune epitopes associated with infectious diseases, autoimmune diseases, commensal organisms, or transplant outcomes. The program will support teams that include immunologists, microbiologists, virologists, and/or clinicians with relevant expertise. The research may also include the development or refinement of T cell epitope prediction tools. Proposals will be evaluated on the scientific merit, approach, innovation, and qualifications of the research team.

This is an unrestricted solicitation with no set-aside designation. The government has not provided any information about potential incumbent contractors or the anticipated award value or budget. The period of performance is not specified, but the proposal due date is July 19, 2023. The research must not be focused on HIV/AIDS or allergen epitopes.

Notice text

The primary purpose of this solicitation is to support highly interactive, multi-disciplinary teams whose research efforts are focused on large-scale discovery of T cell immune epitopes associated with infectious or autoimmune diseases, commensal organisms, or alloantigens influencing transplant outcomes, and validation of these epitopes, and defined mechanisms of T cell immune protection or immune-mediated pathogenesis in humans. Investigators may also include development/refinement of T cell epitope prediction tools as part of their research plan. It is anticipated that the multi-disciplinary teams will minimally include immunologists with the appropriate expertise in epitope identification and validation, and either microbiologists and/or virologists with expertise in the target pathogen(s), or clinicians with expertise in the target autoimmune disease(s) or transplantation immunology, as appropriate. This program will not support studies related to HIV/AIDS or allergen epitopes.

Files

File Type Posted
75N93022R00023_T-Cell_ Amendment 2.pdf PDF
T-Cell_ Amendment 1 4_27 Final.pdf PDF
75N93022R00023_Final.pdf PDF

Notice history

5 of 7 notices listed here. See the rest on GovTribe.

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