Krios G4 Transmission Electron Microscope or Equal Brand

Introduction:

This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement.

Project Summary:

The National Institute of Allergy and Infectious Diseases (NIAID), Structural Biology Core (SBC), Virology Laboratory (VL) within the Vaccine Research Center (VRC), is seeking a Krios G4 Transmission Electron Microscope (TEM) or Equal Brand* instrument to support the design of vaccines and antivirals carried out by the VRC.

NIAID, SBC is seeking a Krios G4 Transmission Electron Microscope instrument or Equal Brand* that includes:

- High-Stability High-Tension Generator

- Automatic Aperture System

- C-TWIN Lens

- AutoLoader

- CompuStage with Krios Single-Axis Holder

- Flu Camera

- Workstation with 3x 24’’ LCD Monitor

- 300 kV Alignment

- Linear Distortion Correction

- Smart EPU Software

- EPU MultiGrid

- Data Management Platform

- TEM Scripting

- Advanced TEM Scripting Academic License

- Velox Imaging Software

- 2x Capsules

- 4x Cassettes

- 1x C-Clip Ring (100x)

- 1x C-Clip (100x)

- 4x C-Clip Insertion Tools

- 1x Loading Station

- 1x AutoGrid Alignment Tool

- 1x AutoGrid Tweezers

- 1x AutoGrid Container (20x)

- 1x Cassette Tweezers

- 1x AutoGrid Assembly Workstation

- 1x Grid Container Tool

-System Column

-System Enclosure

-Deflector/Stigmator Unit

-Remote Monitoring Station

-Network Computer

Electron Source:

- E-CFEG

Detectors:

- Ceta-D Camera 300 kV

- Selectris X with Falcon 4i for 300 kV

Sample Prep:

- Vitrobot

Application MicroED:

- MicroED Package

Application SPA:

- Smart EPU with Quality Monitor

Application Tomography:

- TEM Tomography Data Acquisition Software

- Tomo Live

- Inspect3D Xpress

- Maps 3 for S/TEM with Correlative Workflow

- Maps 3 Offline with Correlative Workflow

- Amira for EM Systems (Life Sciences) - Floating, 2-users license

Environmental Remediation:

- AVI - STACIS iX TOOL-Base Piezoelectric Active Vibration Platform for Spectra/G4 mount directly on floor - 25T-63340-01 (incl. initialization, excl. physical install.)

- EMI - Magnetic Field Cancelling System SC24/TEM/DL System with 2 DC sensors and DL cables for TEM in room (excl. install) - SP624028

- INSTALLATION - Install cancelling system with double loop room cables for TEM - worldwide - SP703004

Shipping:

-VRC Building 40, Bethesda, MD 20814

Installation & Warranty:

- Compressor 115 V, 50/60 Hz

- S2 Compliant Chiller (Water Enhanced)

- Site Preparation Support - Existing Facility

- Power supply UPS 4400 series,15kVA

- Riggers for Inside Delivery

- Installation Labor Krios G4 NA

- Installation Material Krios G4 NA

- Warranty Labor Krios G4 NA

- Warranty Material Krios G4 NA

- Global Installation Kit FEG

-Manufacturer’s Warranties

Training & Support:

Accelerate Plus SPA TEM LS NA

- Workflow validation using a biological sample

- One hundred (100) hours of remote support

- Twenty (20) days of on-site application support

- Regular monitoring of system health

- Quarterly Reviews to discuss system trends

- Workflow Assistant App

- Customer Success Manager

- Connected Care Portal

-Certified Personnel to Install and Maintain the Equipment

Specifications:

THIS IS THE MAXIMUM SIZE ALLOWANCE

-Fully Assembled Height: 10ft

-Total Space: 17’ X 22’

-Total Net Weight: 10,669lb

Anticipated Period of Performance

Estimated Final Delivery is April 2027. The total estimated performance period, which includes manufacturing, delivery, installation, and deployment, is September 2026 to January 2027. An Installation schedule is required when notified 5 months from the delivery of the equipment.

Capability Statement/Information Sought

If your organization has the potential capacity to provide a Krios G4 Transmission Electron Microscope or Equal Brand* which meets the minimum salient characteristics listed above, please provide the following information:

1. 1. Organization name, address, point of contact, email address, website address, telephone number, UEI number
   2. Type of business (e.g., 8(a), HUBZone, Other than Small, etc.) pursuant to the applicable NAICS code
   3. Identification of any Best-in-Class contract vehicles including Government Wide Acquisition Contracts (GWAC) (e.g., GSA schedule, NITAAC) they may possess or are aware of that would support this possible requirement. If your organization does not provide the products/services under a GWAC, please identify availability as OPEN MARKET ONLY.
   4. Tailored capability statement addressing the capability of the instrument to meet NIAID’s minimum salient characteristics. Capability document shall be no more than six pages.
   5. Place of manufacture for the microscope and if applicable, any accessories/components.
   6. Evidence that the organization is an authorized reseller or manufacturer of the instrument. Only Original Equipment Manufacturer (OEM) products are acceptable.

Submission Instructions

Interested businesses who consider themselves qualified to provide the above listed Krios G4 Transmission Electron Microscope or Equal Brand* are invited to submit a response to this Sources Sought Notice by December 17, 2024, at 3:00 PM EST. All responses under this Sources Sought Notice shall be emailed to Angela Raco at angela.raco@nih.gov.

Disclaimer and Important Notes

This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality

No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).

*Should you have any questions regarding Brand Equal, please reference FAR 52.211-6.