Independent Validation and Verification (IV&V) Services for the REACT Program
Closed Solicitation Posted
This opportunity was awarded. See the award notice from .
- Solicitation number
- 75N99226R00001
- Agency
- National Institutes of Health Department of Health and Human Services
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541990 All Other Professional, Scientific, and Technical Services
- Place of performance
- Washington, District of Columbia, United States
- Points of contact
-
- Clare Sanchez clare.sanchez@arpa-h.gov
- Larin Harris larin.harris@arpa-h.gov
Notice details come from SAM.gov. Updated .
About this opportunity
The Department of Health and Human Services National Institutes of Health, specifically the Advanced Research Projects Agency for Health (ARPA-H) Resilient Systems Office (RSO), is seeking independent validation and verification (IV&V) services for its Resilient Extended Automatic Cell Therapies (REACT) program. The REACT program is developing wireless implantable medical devices designed to enable surveillance and treatment of chronic diseases with potential for commercialization as affordable healthcare solutions. The IV&V services are critical to achieving standardization and reproducibility of engineered cell lines that form the foundation of two primary devices: the "Living Pharmacy," which delivers tunable therapeutic molecules on demand, and the "Living Sentinel," which tracks disease biomarker status. These IV&V services will support the program's objective to scale up manufacturing capability for both devices. The solicitation was posted on November 24, 2025, with proposals due by January 5, 2026. This is a combined synopsis and solicitation for commercial products or services prepared in accordance with Federal Acquisition Regulation Part 12, and no separate written solicitation will be issued.
This opportunity carries no set-aside designation and is classified under NAICS code 541990 (All Other Professional, Scientific, and Technical Services) and PSC code B537 (Special Studies/Analysis–Medical/Health). The place of performance is Washington, DC, USA. The specific award value, budget range, contract duration, and timeline for service delivery have not been disclosed in this solicitation notice; contractors should refer to the attached government files, including the Performance Work Statement (PWS) for IV&V for REACT and the primary solicitation document (A05A_75N99226R00001.pdf), for comprehensive details on evaluation criteria, detailed requirements, and all contractual terms and conditions. Additionally, an HHS Subcontracting Plan Template has been provided as an attachment, indicating that subcontracting requirements may apply to interested offerors.
Notice text
This is a combined synopsis/solicitation for commercial products or commercial services prepared in accordance with part 12. This announcement constitutes the only solicitation. Offers are being requested and a separate written solicitation will not be issued.
Please refer to the attachments for full details.
The Advanced Research Projects Agency for Health (ARPA-H) Resilient Systems Office (RSO) requires independent validation and verification (IV&V) services for its Resilient Extended Automatic Cell Therapies (REACT) program. The REACT program is developing wireless implantable medical devices for the surveillance and treatment of chronic diseases that can ultimately make it to the commercial market as an affordable health care device. The objective is for the devices to interface with patients through a software platform, allowing for confirmation of therapy delivery or current disease status. The “Living Pharmacy” device will deliver tunable therapeutic molecules on demand, while the “Living Sentinel” device will track disease biomarker status. A critical component of the devices is engineered and/or differentiated cell lines (herein, “cells”) that deliver therapies or track biomarker status, respectively. IV&V is required by the REACT team to achieve standardization and reproducibility of cells so the program can scale up the manufacturing capability for the Living Pharmacy and Living Sentinel.
Attachments
| File | Type | Posted |
|---|---|---|
| A05A Attachment 1- PWS IVV for REACT.pdf | ||
| A05A Attachment 2 HHS Subcontracting Plan Template.docx | DOCX document | |
| A05A_75N99226R00001.pdf |
Notice history
| Notice | Type | Posted |
|---|---|---|
| Independent Validation and Verification (IV&V) Services for the REACT Program | Award Notice | |
| Independent Validation and Verification (IV&V) Services for the REACT Program | Solicitation |
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