Human Discovery Panel (HDP) analysis to obtain single cell multiomic data

Closed Pre-Solicitation Posted

Solicitation number
75N95025Q00238SB
Agency
Responses due
Set-aside
Total Small Business

Opportunity facts

Place of performance
Rockville, Maryland 20850, United States

Notice details come from SAM.gov. Updated .

About this opportunity

The National Institute on Drug Abuse (NIDA), acting on behalf of the National Center for Advancing Translational Sciences (NCATS), is seeking capability statements from qualified businesses to perform Human Discovery Panel (HDP) analysis to obtain single-cell multiomic data. The procurement involves preparing and sequencing 33 samples of human pluripotent stem cell-derived sensory neurons under different inflammatory conditions using a single-cell multinomics platform capable of analyzing up to 325 distinct proteins. Vendors must demonstrate the ability to provide specific equipment including 2 MultiPro Human Discovery Panels, 8 MultiPro Human Enhanced Blocking Reagents, and 1 Genomics Analysis Service. Capability statements must include comprehensive details about company employees, professional qualifications, government contract vehicles, and manufacturing capabilities, with each project requirement addressed separately. The deadline for electronic submission of capability statements to Andrew Varley at Andrew.Varley@nih.gov is August 12, 2025, at 11:00 AM Eastern Time.

This opportunity is designated as a Total Small Business set-aside under NAICS code 541380 for Testing Laboratories and Services, and the government is specifically seeking to identify various categories of small businesses including HUBZone, service-disabled veteran-owned, 8(a), veteran-owned, woman-owned, and small disadvantaged businesses. The procurement involves processing 33 biological samples with sophisticated single-cell analysis technology, representing a specialized scientific testing requirement. No incumbent contractors or potential award values are specified in this sources sought notice, as this is an information-gathering phase rather than a formal solicitation. The government will use the responses to determine the appropriate acquisition method and assess whether maintaining the small business set-aside designation is feasible based on the pool of qualified vendors. The technical complexity of the work involves advanced genomics analysis services and specialized laboratory equipment for cellular research applications.

Notice text

The National Institute on Drug Abuse (NIDA) on behalf of the National Center for
Advancing Translational Sciences (NCATS) is seeking Capability Statements from
Business organizations under the North American Industry Classification System
(NAICS) code 541380, Testing Laboratories and Services. 

This is a Small Business Sources Sought notice. This is NOT a solicitation for
proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain
information regarding: (1) the availability and capability of qualified small business
sources; (2) whether they are small businesses; HUBZone small businesses; servicedisabled,
veteran-owned small businesses; 8(a) small businesses; veteran-owned small
businesses; woman-owned small businesses; or small disadvantaged businesses; (3)
their size classification relative to the North American Industry Classification System
(NAICS) code for the proposed acquisition; Your responses to the information requested
will assist the Government in determining the appropriate acquisition method, including
whether a set-aside is possible. The established NAICS code is 541380 - Testing
Laboratories and Services.

Files

File Type Posted
SBSSN.pdf PDF

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