Gene Expression and Gene Editing - Beltsville, MD
Closed Solicitation Posted
This opportunity was awarded. See the award notice from .
- Solicitation number
- 1232SA25Q0463
- Agency
- Agricultural Research Service Department of Agriculture
- Responses due
- Set-aside
- Total Small Business
Opportunity facts
- NAICS code
- 541713 Research and Development in Nanotechnology
- Place of performance
- Beltsville, Maryland 20705, United States
- Points of contact
-
- Shane Pope shane.pope@usda.gov (970) 851-3735
Notice details come from SAM.gov. Updated .
About this opportunity
The USDA Agricultural Research Service is seeking gene expression and gene editing services for their Soybean Genomics and Improvement Laboratory in Beltsville, Maryland through solicitation number 1232SA25Q0463. The procurement involves two primary components: using a single vector to express four genes in rice and corn varieties, requiring gene synthesis, vector construction, plant transformation, and gene expression validation to obtain T1 generation seeds from at least 10 confirmed positive lines; and changing a single base pair in a soybean gene from "A" to "C" to obtain T1 generation seeds from at least three mutant lines. Contractors must demonstrate recent relevant experience and provide detailed technical proposals, qualified technician verification, and at least two references. The evaluation will use a Lowest Price Technically Acceptable (LPTA) methodology considering technical acceptability, past performance, and price. Quotes must be submitted via email to shane.pope@usda.gov by August 7, 2025 at 5:00 p.m. CT.
This opportunity is set aside 100% for small businesses under NAICS code 541713 with a size standard of 1,000 employees, and no incumbent contractor is identified in the solicitation materials. The contract period of performance is anticipated to be 10-12 months with specific milestones including vector construction, Agrobacterium transformation, positive transformant screening, and validation through antibiotic resistance and PCR tests. The planned contract delivery date is September 30, 2026, and the government intends to award a single firm-fixed price purchase order. Work will be performed for delivery to the USDA-ARS Soybean Genomics and Improvement Laboratory at Building 006, Room 100 in Beltsville, Maryland. The project aims to improve nutrition, seed quality, and other traits in legume crops by examining the relationship between gene expression and phenotype, with deliverables including protocols, experimental designs, confirmation test results, and T1 generation seeds.
Notice text
This is a combined synopsis/solicitation for commercial item prepared in accordance with the format in FAR subpart 12.6 and FAR Part 13, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested, and a written solicitation will not be issued. The solicitation number is 1232SA25Q0463 and is issued as a request for quotation (RFQ). This solicitation document incorporates those provisions and clauses in effect through Federal Acquisition Circular 2025-04. The associated NAICS Code is 541713 and the Small Business Size Standard is 1,000 employees.
The USDA, Agricultural Research Service, requires Gene Expression and Gene Editing Services for USDA ARS Soybean Genomics and Improvement Laboratory in Beltsville, MD. The Government intends to award a single firm-fixed price purchase order.
The requirements are further detailed in the attached Requirements Document.
The DELIVERY ADDRESS is:
USDA-ARS Supervisory Research Geneticist
Soybean Genomics and Improvement Laboratory
Building 006, Rm 100
Beltsville, MD 20705
DOCUMENTS TO BE INCLUDED IN QUOTE: In order to be considered for award, Offerors shall respond by:
1. Providing a quote on company letterhead addressing all documents identified in the RFQ according to requirements as defined in section FAR 52.212-1 Addendum Submission documents, clearly note per item pricing, with all associated costs to include but not limited to shipping/handling/delivery price, and be valid for at least 60 days after receipt of quote.
2. Any amendment and documents related to this procurement will be available electronically at the Government Point of Entry (sam.gov).
FAR clauses 52.211-6, 52.212-1, 52.212-2, 52.212-3, 52.212-4 and 52.212-5 (and any addenda to those clauses) are included in the attached clauses and provisions document. Additionally, other contract requirements and terms/conditions can be located in the same document.
The Government anticipates award of a contract resulting from this solicitation to the responsible offerors whose quote conforms to the specifications that will be the most advantageous to the Government in accordance with FAR 13.106-2 considering three major areas: technical acceptance, past performance and price. Quotes will be evaluated by performing a comparative evaluation in accordance with FAR 13.106-2(b)(3) to determine which quote meets the lowest price technically acceptable evaluation methodology.
All sources wishing to quote shall furnish a quotation on or before the date identified on the solicitation document. Quotations are to be sent via email to Shane Pope at shane.pope@usda.gov .
Failure to provide the required information in the requested format may result in quotes not being considered for award.
Attached Provisions/Clauses apply to this RFQ and any subsequent award.
Attachments
| File | Type | Posted |
|---|---|---|
| Attachment 1 Statement of Work SOW 1232SA25Q0463.pdf | ||
| Sol_1232SA25Q0463.pdf | ||
| Attachment 2 SCA WD 2015-4281 Rev 34 Dated 08 July 2025 Prince George County MD.pdf |
Notice history
| Notice | Type | Posted |
|---|---|---|
| Gene Expression and Gene Editing - Beltsville, MD | Award Notice | |
| Gene Expression and Gene Editing - Beltsville, MD | Solicitation |
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