Functional MRI following Transcranial Direct Current Stimulation (tDCS)

Closed Pre-Solicitation Posted

Solicitation number
75N98026Q00876
Agency
Responses due
Set-aside
No set-aside

Opportunity facts

Place of performance
Bethesda, Maryland 20892, United States

Notice details come from SAM.gov. Updated .

About this opportunity

The National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, intends to solicit functional magnetic resonance imaging services supporting a clinical research protocol, with a pre-solicitation notice response deadline of August 3, 2026.

The requirement spans four fMRI brain scans—two scans per session for two study participants—performed before and after transcranial direct current stimulation. Services include image acquisition, preprocessing and validation, data transfer and processing, quality control, region of interest and whole-brain statistical analysis, and a written analysis report. Personnel must demonstrate expertise in neuroimaging methods. All acquired and processed imaging data must be delivered in formats compatible with NIH's neuroimaging software; NIH retains responsibility for data management and long-term storage.

Place of performance is the Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, located at 850 North 5th Street, 7th Floor, Phoenix, Arizona 85004. Period of performance runs from August 31, 2026 through August 30, 2027.

The procurement is classified under NAICS 541990 (All Other Professional, Scientific, and Technical Services) and PSC R499 (Support—Professional: Other). No set-aside applies.

Notice text

Requirements rev5 

Functional MRI following Transcranial Direct Current Stimulation (tDCS) 

2.0 BACKGROUND 

As part of the ongoing study protocol, “The Effects of Transcranial Direct Current Stimulation on Food Intake and Weight Loss” (ClinicalTrials.gov Identifier NCT00739362), the Obesity and Diabetes Clinical Research Section of the Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, located at 850 North 5th Street, 7th Floor, Phoenix, Arizona 85004, requires functional magnetic resonance imaging of the brain to be performed before and after transcranial direct current stimulation. 

The required services include acquisition of high-quality functional magnetic resonance imaging data, image preprocessing, quality control, and statistical analysis performed by personnel with demonstrated expertise in neuroimaging methods. These services are necessary to evaluate changes in brain activity associated with transcranial direct current stimulation, confirm engagement of the intended brain regions, and support the scientific objectives of the clinical research protocol. 

3.0 OBJECTIVE 

The objective of this study is to evaluate the effects of transcranial direct current stimulation applied to the left dorsolateral prefrontal cortex on brain activity and food intake. Functional magnetic resonance imaging will be performed before and after stimulation to confirm target engagement and measure changes in neural activity associated with the intervention. 

4.0  CONTRACTOR REQUIREMENTS  

The contractor shall provide functional magnetic resonance imaging services consisting of four functional magnetic resonance imaging scans of the brain (two scans per session for two study participants) and analysis of the completed imaging data. 

The required services shall include: 

  • Image preprocessing and validation. 

  • Data transfer, processing, and quality control. 

  • Region of interest and whole-brain statistical analysis. 

  • Preparation and delivery of a written analysis report summarizing the imaging results. 

The contractor shall provide the National Institutes of Health with copies of all acquired neuroimaging data and all processed imaging data and analysis results in a format compatible with the National Institutes of Health's available neuroimaging software. The National Institutes of Health shall be responsible for data management and long-term storage following delivery and acceptance of the final results. 

The period of performance is 08/31/2026-08/30/2027

Files

File Type Posted
Requirements rev5.pdf PDF

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