Fiber Photometry Processors

Closed Pre-Solicitation Posted

Solicitation number
NIMH25001743
Agency
Responses due
Set-aside
Total Small Business

Opportunity facts

Place of performance
Bethesda, Maryland 20892, United States

Notice details come from SAM.gov. Updated .

About this opportunity

The National Institute on Drug Abuse (NIDA), part of the Department of Health and Human Services, is seeking Fiber Photometry Processors (RZ5P) for neuroscience research focused on understanding substance use disorder. These specialized computer processors are designed for data acquisition and processing, capable of modulating different wavelengths of light at specific sinusoidal frequencies up to 50 KHz. The processors will enable the Laboratory on Neurobiology of Compulsive Behaviors (LNCBA) to record fluorescent neurotransmitters like dopamine during animal behavior experiments. Small businesses are invited to submit capability statements demonstrating their technical qualifications by January 29, 2025, at 9:00am ET, with responses limited to 10 pages and to be submitted electronically to joseph.kennedy@nih.gov. Respondents must address manufacturing location and size status requirements within the NAICS 334519 category with a size standard of 500 employees.

The procurement is designated as a Total Small Business set-aside, targeting manufacturers of measuring and controlling devices. While no specific award value is disclosed, the anticipated period of performance is 12 months. The RZ5P processors feature two 400 MHz Sharc digital signal processors, six analog input channels, four analog output channels, a fiber optic input port, 24-bit digital I/O, and specialty control software. Potential contractors must provide detailed capability statements that include their qualifications, employee count, technical capabilities, and business classification status. This Sources Sought notice is a preliminary market research step and does not constitute an actual solicitation, meaning no contract will be awarded directly from this notice.

Notice text

The RZ5P is a computer processor built specifically for fiber photometry data acquisition and processing. This process involves modulating different wavelengths of light at very specific sinusoidal frequencies and then receiving that signal back, at rates of up to 50 KHz, and demodulating it in real time. The Synapse software and accompanying computer card are required to control the processor.

The Laboratory on Neurobiology of Compulsive Behaviors (LNCBA) aims to understand the causes of substance use disorder (SUD). These processors enable us to record fluorescent neurotransmitters (dopamine, for example) while animals learn and perform behaviors and/or are administered substances commonly misused in SUD. Through these experiments, we learn how dopamine and other neurotransmitters are altered by specific behaviors and substances.

Files

File Type Posted
D_25-001743_Sources Sought.pdf PDF

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