Developing Mathematical Models to Simulate the Effects of Physical Activity on Cardiovascular Incidence and Mortality among Breast Cancer Survivors

The National Institute of Child Health and Human Development (NICHD) within the Department of Health and Human Services is seeking to procure mathematical modeling services to simulate the effects of physical activity on cardiovascular incidence and mortality among breast cancer survivors. This non-competitive contract award is specifically targeted at Albert Einstein College of Medicine and Dr. Clyde Schechter, a recognized researcher with extensive experience in Bayesian statistics and mathematical modeling. The procurement is classified under NAICS code 541990 for professional, scientific, and technical services, with the objective of developing an innovative mathematical module for assessing cardiovascular event risk in breast cancer survivors to support Dr. Jayasekera's Decision Sciences Lab at the National Institute on Minority Health and Health Disparities. Interested parties must submit capability statements, technical proposals, cost-price proposals, and other required documentation electronically to Mr. Michael Falzone. All offerors must maintain active registration in the System for Award Management (SAM), with responses due by September 20, 2025 at 9:00 AM Eastern time.

This procurement operates under simplified acquisition procedures with no set-aside designation, indicating it is open to all eligible contractors regardless of small business status or other socioeconomic categories. The contract is structured as a sole source award specifically naming Albert Einstein College of Medicine as the intended recipient, suggesting an existing relationship or unique capability that justifies the non-competitive approach. The contract value is established under the simplified acquisition threshold of $250,000, indicating a relatively modest budget for this specialized mathematical modeling work. The procurement timeline is compressed, with only a ten-day response period from the posting date of September 10, 2025 to the submission deadline of September 20, 2025, reflecting the targeted nature of this sole source acquisition.