CureSCi Long-Term Follow-Up (LTFU) Consortium: Coordinating Center Activities

The National Institutes of Health National Heart, Lung, and Blood Institute intends to solicit a coordinating center contract for the CureSCi Long-Term Follow-Up Consortium and operation of the Sickle Cell Disease Natural History Data Resource, with capability statements due October 2, 2026. This procurement is restricted to small businesses certified under NAICS 541715 (Research and Development in the Physical, Engineering, and Life Sciences). The Government anticipates awarding one contract for a ten-year period, with an approximate award date in April 2028.

The contractor will manage comprehensive NHDR operations, including longitudinal data collection from sickle cell disease patients serving as comparators for gene therapy and hematopoietic cell transplant recipients. Core responsibilities span participant retention and clinical data collection, patient-reported outcomes management, biospecimen collection, data management and quality control, analysis and reporting, multi-center site coordination, and coordinating center functions (data strategy, meeting coordination, website maintenance, metadata catalog management, and publications support). The contractor must demonstrate multi-center clinical study management expertise, appropriate data management and informatics capabilities, and compliance with federal, NIH, and NHLBI requirements including human subjects protections and privacy standards.

Interested small businesses must submit capability statements electronically to Elizabeth Bulger (elizabeth.bulger@nih.gov) and Jessica Williams (jessica.williams3@nih.gov), referencing Sources Sought Notice number 75N98026R00150. Statements must not exceed 15 single-sided or 7.5 double-sided pages in 12-point font and must address each project requirement, total employee count, key personnel qualifications, facility and equipment descriptions, relevant prior research experience, and contact information for a knowledgeable point of contact.