AJ13--Pharmarcokinetics for Experimental Rheumatoid Arthritis treatment
Closed Pre-Solicitation Posted
- Solicitation number
- 36C24526Q0669
- Agency
-
Veterans Integrated Service Network 5
Veterans Health Administration, Department of Veterans Affairs
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 112990 All Other Animal Production
- PSC
- AJ13 General Science & Technology R&D Svcs; General Science & Technology; Experimental Development
- Place of performance
- Contractor's Lab/Facility See Sources Sought Notice for Details 21218, United States
- Points of contact
Notice details come from SAM.gov. Updated .
About this opportunity
The Department of Veterans Affairs, Network Contracting Office 05, intends to solicit preclinical toxicology and pharmacokinetic studies to support development of an experimental joint-targeted liposomal delivery system for rheumatoid arthritis therapy, with a response deadline of July 31, 2026. No set-aside is anticipated.
Work will be performed at the contractor's laboratory. The contractor must perform GLP-compliant single-dose intravenous toxicity studies in adult rats, including clinical observations, weight and food intake monitoring, blood chemistry assessments, necropsy, and histopathology. Pharmacokinetic studies—conducted under GLP or non-GLP protocols—must include intravenous dosing, timed blood collection, plasma processing and storage, LC-MS/MS analysis of dexamethasone and 6-hydroxydexamethasone, and PK parameter calculations. The contractor must deliver a comprehensive final written report covering toxicity results, PK data, and analytical findings.
The anticipated period of performance is one year, from September 15, 2026 through September 14, 2027. The formal solicitation will follow completion of market research and is not yet released. The NAICS code is 112990 (All Other Animal Production); the PSC is AJ13 (General Science & Technology R&D Services). Point of contact: Robert O'Keefe Jr., Contract Specialist, robert.okeefejr@va.gov.
Notice text
PRE SOLICITATION NOTICE
Department of Veterans Affairs Network Contracting Office (NCO) 05
Title: A Joint Targeted Drug Delivery Approach for Arthritis Therapy Toxicity and Pharmacokinetics
The Department of Veterans Affairs (VA), Network Contracting Office (NCO) 05, intends to issue a solicitation for preclinical toxicology and pharmacokinetic (PK) studies to support advancement of an experimental joint targeted liposomal delivery system for Rheumatoid Arthritis therapy. This requirement involves GLP compliant toxicity studies and GLP or non GLP PK studies in adult rats.
The forthcoming solicitation will seek a contractor capable of performing:
GLP single dose IV toxicity studies including clinical observations, weight/food intake monitoring, blood chemistry assessments, necropsy, and histopathology.
GLP or non GLP pharmacokinetic studies including IV dosing, timed blood collection, plasma processing and storage, LC MS/MS analysis of dexamethasone and 6 hydroxydexamethasone, and calculation of PK parameters.
A comprehensive final written report covering toxicity results, PK data, and analytical findings.
Place of performance will be the contractor s laboratory. The anticipated period of performance is one year, approximately September 15, 2026 through September 14, 2027.
This notice is issued solely for informational purposes. A formal solicitation and the Government s acquisition strategy will be issued after completion of market research.
This notice does not constitute a solicitation and does not commit the Government to award a contract.
Point of Contact:
Robert O Keefe Jr., Contract Specialist
Email: robert.okeefejr@va.gov
Files
| File | Type | Posted |
|---|---|---|
| 36C24526Q0669_1.docx | DOCX document |
Notice history
| Notice | Type | Posted |
|---|---|---|
| This notice | Pre-Solicitation | |
| AJ13--Pharmarcokinetics for Experimental Rheumatoid Arthritis treatment | Pre-Solicitation |
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