36C24526Q0669_1.docx
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- Solicitation number
- 36C24526Q0669
About this file
This is a Presolicitation Notice issued by the Department of Veterans Affairs, Network Contracting Office (NCO) 05, announcing an upcoming solicitation for preclinical toxicology and pharmacokinetic (PK) studies. The VA intends to procure services to support advancement of an experimental joint-targeted liposomal delivery system for Rheumatoid Arthritis therapy, with work to be performed at the contractor's laboratory. The anticipated period of performance is one year, commencing September 15, 2026, and concluding September 14, 2027.
The required services include GLP-compliant single-dose intravenous toxicity studies in adult rats encompassing clinical observations, weight and food intake monitoring, blood chemistry assessments, necropsy, and histopathology; GLP or non-GLP pharmacokinetic studies involving intravenous dosing, timed blood collection, plasma processing and storage, LC-MS/MS analysis of dexamethasone and 6-hydroxydexamethasone, and PK parameter calculations; and a comprehensive final written report documenting toxicity results, PK data, and analytical findings. The solicitation number is 36C24526Q0669, with a product/service code of AJ13 and NAICS code 112990. The contracting office is located in Perry Point, Maryland (ZIP code 21902), and the point of contact is Robert O'Keefe Jr., Contract Specialist, at robert.okeefejr@va.gov. This presolicitation notice is issued for informational purposes only and does not constitute a formal solicitation or commitment to award a contract; the formal solicitation will follow completion of market research.
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Text version
Presolicitation Notice Presolicitation Notice
| SUBJECT* |
| Pharmarcokinetics for Experimental Rheumatoid Arthritis treatment |
GENERAL INFORMATION
| CONTRACTING OFFICE’S ZIP CODE* |
| 21902 |
| SOLICITATION NUMBER* |
| 36C24526Q0669 |
| RESPONSE DATE/TIME/ZONE |
| 07-31-2026 9:00am EASTERN TIME, NEW YORK, USA |
| ARCHIVE |
| 60 DAYS AFTER THE RESPONSE DATE |
SET-ASIDE
| PRODUCT SERVICE CODE* |
| AJ13 |
| NAICS CODE* |
| 112990 |
| PLACE OF PERFORMANCE |
| Contractor's Lab/Facility |
See Sources Sought Notice for Details
| POSTAL CODE |
| 21218 |
| COUNTRY |
| USA |
CONTACT INFORMATION
CONTRACTING OFFICE ADDRESS
Department of Veterans Affairs VA Maryland Health Care System Contracting Officer (90C) P.O. Box 1000, Bldg. 101, Room 26 Perry Point MD 21902
POINT OF CONTACT*
Contracting Officer Robert O'Keefe Jr.
robert.okeefejr@va.gov
ADDITIONAL INFORMATION
AGENCY’S URL
https://www.va.gov/maryland-health-care/locations/baltimore
| URL DESCRIPTION |
| Homepage |
AGENCY CONTACT’S EMAIL ADDRESS
EMAIL DESCRIPTION
DESCRIPTION
PRE‑SOLICITATION NOTICE
Department of Veterans Affairs – Network Contracting Office (NCO) 05 Title: A Joint‑Targeted Drug Delivery Approach for Arthritis Therapy – Toxicity and Pharmacokinetics
The Department of Veterans Affairs (VA), Network Contracting Office (NCO) 05, intends to issue a solicitation for preclinical toxicology and pharmacokinetic (PK) studies to support advancement of an experimental joint‑targeted liposomal delivery system for Rheumatoid Arthritis therapy. This requirement involves GLP‑compliant toxicity studies and GLP or non‑GLP PK studies in adult rats.
The forthcoming solicitation will seek a contractor capable of performing:
· GLP single‑dose IV toxicity studies including clinical observations, weight/food intake monitoring, blood chemistry assessments, necropsy, and histopathology.
· GLP or non‑GLP pharmacokinetic studies including IV dosing, timed blood collection, plasma processing and storage, LC‑MS/MS analysis of dexamethasone and 6‑hydroxydexamethasone, and calculation of PK parameters.
· A comprehensive final written report covering toxicity results, PK data, and analytical findings.
Place of performance will be the contractor’s laboratory. The anticipated period of performance is one year, approximately September 15, 2026, through September 14, 2027.
This notice is issued solely for informational purposes. A formal solicitation and the Government’s acquisition strategy will be issued after completion of market research.
This notice does not constitute a solicitation and does not commit the Government to award a contract.
Point of Contact:
Robert O’Keefe Jr., Contract Specialist Email: robert.okeefejr@va.gov
Presolicitation Notice
Presolicitation Notice
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