12258238 -Synopsis/Solicitation for Bayesian precision dosing software system
Closed Solicitation Posted
- Solicitation number
- 12258238
- Agency
-
Defense Health Agency
Department of Defense
- Responses due
- Set-aside
- Total Small Business
Opportunity facts
- NAICS code
- 518210 Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services
- Place of performance
- Bethesda, Maryland 20889, United States
Notice details come from SAM.gov. Updated .
About this opportunity
The Defense Health Agency is seeking a cloud-based Bayesian precision dosing software system for the Department of Pharmacy at Walter Reed National Military Medical Center (WRNMMC). The software will support precise calculation of drug dosing regimens, specifically for medications with narrow therapeutic windows like vancomycin, by predicting future area-under-curve (AUC) or serum levels and providing toxicity probability functions. Quotes will be evaluated based on price, technical acceptability, and conformity to solicitation requirements, with the intent to award to the most advantageous offer. The solicitation is being conducted under NAICS code 518210 for Computing Infrastructure providers, with offers due by May 23, 2025, at 1:00 PM EST. The contract will require compliance with HIPAA and DoD cybersecurity standards, and the support team must include subject matter experts with pharmacokinetics expertise, credentialed as PharmD, FRCP, or MPH.
The solicitation is a 100% small business set-aside, with a five-year performance period from June 1, 2025, to May 31, 2030, structured in annual 12-month increments. The place of performance is located in Bethesda, MD 20889, and the contract includes a 12-month base period with four potential one-year option periods. The software system must be implemented within 60 days of contract award and provide a secure, cloud-based Software as a Service (SaaS) platform with robust pharmacokinetic models, real-time PK advisories, dose assist features, and an interactive analytics dashboard. While specific award values are not explicitly stated, the system is expected to enable clinical decision support, support antimicrobial stewardship, and reduce provider and pharmacy staff workload. The primary point of contact for this solicitation is Contract Specialist Cinthia Funes, and the procurement will incorporate various Federal Acquisition Regulation (FAR) and Defense Federal Acquisition Regulation Supplement (DFARS) provisions.
Notice text
The department of Pharmacy at Walter Reed National Military Medical Center (WRNMMC) has a requirement for a Bayesian precision dosing software system that calculates precise dosing regimens in order to predict future area -under-curve (AUC) or serum levels and provides toxicity probability functions that assists with precision dosing of drugs with narrow therapeutic window such as vancomycin in accordance with the PWS
Files
| File | Type | Posted |
|---|---|---|
| 55- Solicitation 12258238 PWS.docx | DOCX document | |
| 55- Synopsis-Soliciation Combo (PR 12258238).docx | DOCX document |
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