specs.pdf

PDF 94 KB Posted

Attached to
Custom Synthesis of 6-13C-Ketamine
Solicitation number
NIH-OLAO-OD5-NOI6136217
Issued by

View the file

On GovTribe

Work with this file

  • Download the original file
  • Contacts named in this file
  • Similar government files
  • Ask GovTribe AI about this file
Try for free Login

Text version

The file's text, extracted by GovTribe without its formatting.

SPECIFICATIONS:

6-13C-Ketamine 500 mg

NIMH MIB requires labelled 6-13C Ketamine Hydrochloride in order to perform in vivo NMR experiments on rodents.

NIMH’s MR Spectroscopy Unit and Core have been conducting several in vivo carbon-13 (13C) spectroscopy projects with infusion of 13C labeled chemicals. Because natural abundance of 13C is only 1%, the 13C signal is too weak to be detected. Therefore, chemicals with enriched 13C are needed to increase 13C signal intensity.

With these 13C labelled chemicals, NIMH will be able to detect brain metabolism and to accurately measure the concentrations of several important metabolites. Without this chemical, the institute will lose a powerful method in neural science research.

File details come from the government source that posted it. Updated .