Sol_75N98026Q01105.pdf

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ADDENDA

ADDENDA

75N98026Q01105

See Schedule See Schedule

National Institutes of Health Div. Simplified Acq. Policy & Services, OALM 6701 Rockledge Drive, RK II, 4th floor Bethesda, MD 20817

09/04/2026 1500 ED

ROXANE BURKETT

+1 000 000 0000

OD/OALM

ADM-NHLBI

ROXANE S. BURKETT

333310

1,000

08/27/2026

ADMINISTERED BY:

National Institutes of Health

National, Heart, Lung and Blood

Institute

Bethesda MD 20892-7511 US

Camera and Objective Upgrades for Nikon Ti2 W1

Continued...

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COMPLETE PARTIAL FINAL

ACCEPTED,

Spinning-Disc Microscope6

PUBLIC NOTICE OF PROPOSED ACQUISITION

Office of Acquisitions, Office of Management

National Heart, Lung, and Blood Institute

(FAR Subparts 5.101(a)(2))

1. Announcement/Number: 75N98026Q01105

2. Post Date: 08/26/2026

3. Closing Response Date: 09/04/2026

4. Proposed Award Date: 09/28/2026 – 09/27/2027

5. Project Title: Camera and Objective Upgrades for Nikon Ti2 W1 Spinning-Disc Microscope

6. Contracting Office: R&D and Professional Services - Division B, OALM Office of the Director, National Institutes of Health, 6701 Rockledge Drive, Rockledge Building 2, Suite 400, Bethesda, Maryland 20892-7902

7. Contact Point/Contracting Officer/Contract Specialist: Roxane Burkett – roxane.burkett@nih.gov

8. Acquisition Authority: This acquisition is being conducted under Federal Acquisition Regulations (FAR) Part 13 – Simplified Acquisition Procedures, and the resultant contract award will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2026-01.

9. North American Classification System (NAICS) Code: 333314/333310

10. Small business size standard: 1,000 employees

11. Classification Code: 6650

12. Set-aside Status: None, this is a single-sole source (including brand-name) non-competitive action.

mailto:roxane.burkett@nih.gov

13. Description:

The Rusan Laboratory relies on advanced cellular imaging to study centrosomes and the cytoskeleton during mitosis and spermatogenesis. The laboratory currently operates a Nikon Ti2 W1 spinning-disc confocal microscope that is an established component of its imaging infrastructure.

The camera currently installed on the system is approximately three technology generations old and has substantially lower quantum efficiency than current-generation scientific CMOS (sCMOS) cameras. The laboratory's increasing demand for low-light fluorescence imaging requires improved detector sensitivity, acquisition performance, and image quality. The laboratory therefore requires a current-generation sCMOS camera that can be integrated into the existing Nikon Ti2 W1 spinning-disc confocal system.

The laboratory has also adopted expansion microscopy. In this technique, biological specimens are embedded within an expandable gel matrix, resulting in samples that are substantially thicker than conventional cells or tissues. Imaging these specimens requires a microscope objective with sufficient working distance to focus through the expanded sample. The laboratory's existing objectives do not provide the necessary working distance; therefore, a compatible long-working-distance 40X water-immersion objective is required.

These upgrades will allow the laboratory to improve low-light imaging performance and conduct expansion-microscopy experiments using its existing Government-owned microscope rather than acquiring a separate imaging system.

14. Statutory Authority:

This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Subpart 8.4—Federal Supply Schedules, specifically FAR 8.405-6(b), Items Peculiar to One Manufacturer. The Government has determined, based upon market research conducted in accordance with FAR Part 10, that the Nikon Ti2 W1 Spinning-Disc Microscope is essential to the Government’s requirements and that other commercially available products do not meet the Government’s complete minimum requirements.

Pursuant to FAR 8.405-6, orders placed under the Federal Supply Schedule program are exempt from the competition requirements of FAR Part 6.

Accordingly, the Government may restrict consideration to the Nikon Ti2 W1

Spinning-Disc Microscope as a brand-name item when the particular brand-name product or features are essential to the Government’s requirements and the market research supports the restriction.

15. Single-sole Source (Including brand-name) Determination:

The determination by the Government to restrict this acquisition to a brand-name requirement is based upon the market research conducted as prescribed in FAR Part 10—Market Research. Specifically, the results of the market research concluded that the specified Nikon/Photometrics camera and objective upgrade configuration is the only configuration identified as capable of fulfilling the Government’s complete minimum requirements for this acquisition.

The NHLBI Rusan Laboratory currently owns and operates a Nikon Ti2 W1 spinning-disc confocal microscope. This acquisition is not for a new or stand-alone microscope system; rather, it is for a camera and objective upgrade to the existing Government-owned platform. The required components must integrate with the microscope’s existing optical, mechanical, electronic, and software environment, including the spinning-disc configuration, mounting interfaces, acquisition software, drivers, triggering, synchronization, and system controls.

The objective must also provide the long working distance and optical performance necessary for fluorescence imaging of thick specimens produced through expansion microscopy.

Market research determined that commercially available scientific cameras and microscope objectives provide overlapping imaging capabilities. However, the Government’s requirement is not simply for a current-generation sCMOS camera and long-working-distance objective. The required components must have demonstrated compatibility with the installed Nikon Ti2 W1 spinning-disc system and provide the required imaging performance without material modification or replacement of the Government-owned microscope. Market research confirmed that the specified long-working-distance 40X water-immersion objective provides the required optical and mechanical characteristics for the Nikon Ti2 platform and that the specified Kinetix22 camera supports the Nikon acquisition environment and has been demonstrated in Nikon Ti2 spinning-disc configurations.

Use of components that cannot be demonstrated to fully integrate with the installed system could require additional adapters, software, controllers, engineering, or modification of existing equipment and could compromise the functionality of the established imaging platform. The market research did not identify an alternative configuration demonstrated to satisfy the complete combination of compatibility, integration, optical-performance, low-light imaging, and expansion-microscopy requirements.

Accordingly, the specified Nikon/Photometrics camera and objective upgrade configuration is the only configuration identified through market research as capable of satisfying the Government’s complete minimum requirement while preserving interoperability and functionality of the existing Government-owned Nikon Ti2 W1 spinning-disc confocal microscope. For these reasons, the Government will restrict the requirement to the specified brand-name configuration under FAR 8.405-6(b).

16. Closing Statement:

This notice is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice.

Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include:

unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.”

A determination by the Government not to compete this proposed action based upon responses to this notice is solely within the discretion of the Government.

The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

All responses must be received by September 4, 2026 at 3:00PM EST.

Responses must be submitted via email to the Contracting Officer identified above.

“All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.”

http://www.sam.gov/