Sol_75N98026Q00977.pdf

REQUEST FOR QUOTATION

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Prescribed by GSA-FAR (48 CFR) 53.215-1(a)

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IMPORTANT: This is a request for information and quotations furnished are not offers. If you are unable to quote, please so indicate on this form and return it to the address in Block 5a. This request does not commit the Government to pay any costs incurred in the preparation of the submission of this quotation or to contract for supplies or service. Supplies are of domestic origin unless otherwise indicated by quoter. Any representations and/or certifications attached to this Request for Quotation must be completed by the quoter.

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1. REQUEST NUMBER 2. DATE ISSUED 3. REQUISITION/PURCHASE REQUEST NUMBER 4. CERT. FOR NAT. DEF.

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National Institutes of Health OD - Office of Logistics and Acquisition Operations 6100 Executive Blvd., Room 6B05 Bethesda, MD 20892-7511

75N98026Q00977

JADDUA JOHNSTON

+10

000-000000

08/07/2026

08/24/2026 0800 ED

Multiple

The purpose of this COMPETITIVE COMBINED

SYNOPSIS / SOLICITATION is to acquire custom HuCAL recombinant Fab antibody

Period of Performance: 08/31/2026 to

12/31/2026

This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the contracting officer will make their full text available. Also, the full text of a clause may be accessed electronically at this address:

HTTPS://ACQUISITION.GOV/FAR

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OPTIONAL FORM 336 (4-86)

Sponsored by GSA FAR (48 CFR) 53.110

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NSN 7540-01-152-8067

75N98026Q00977

The following FAR clauses and Provisions are applicable to this award.

FAR 52.204-13 System for Award Management

Maintenance (Oct 2018);

FAR 52.204-18 Commercial and Government Entity

Code Maintenance (Aug 2020);

HHSAR 352.222-70, Contractor Cooperation in

Equal Employment Opportunity Investigations

(Dec 2015).

FAR 52.212-4 Contract Terms and Conditions -In addition to all the applicable commercial

Products and Commercial Services (Nov 2023)

FAR 52.212-5 Contract Terms and Conditions

Required to Implement Statutes or Executive

Orders/Commercial Products and Commercial

Services (Jan 2025)

FAR 52.252-2 CLAUSES INCORPORATED BY REFERENCE

Award enclosure:

Quote

IPP Invoicing and Payment Provisions

COMBINED SYNOPSIS / SOLICITATION (COMPETITIVE)

Title: custom HuCAL recombinant Fab antibody

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

(ii) The solicitation number is 75N98026Q00977. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services. The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold (if applicable).

The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, seeks to award a (Firm-Fixed-Price) to the offeror responsible whose proposal represents the best value to the Government.

(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular effective August 7, 2026

(iv) The associated NAICS code is 325414 Biological Product (except Diagnostic) Manufacturing, and the small business size standard is 1250 Employees.

This requirement is unrestricted.

(v) Description of Requirement:

1. Generic Name of Product: Custom recombinant Fab antibody for in vitro research use.

4. Purchase Description and Salient Characteristics:

Trade Name/Brand: HuCAL Recombinant Fab-F-Spy2-H Antibody Manufacturer: Bio-Rad AbD Serotec GmbH Product/Clone: AbD57571pao (derived from clone AbD57571ad) Quantity Required: 2.8 mg

Salient Characteristics:

• Custom recombinant Fab antibody with DYKDDDDK, Spy2, and His-6 tags.

• Coupled Fab antibody format produced using SpyTag/SpyCatcher technology.

• Specific for a 17-amino-acid peptide derived from PEDF protein.

• Purified using affinity chromatography.

• Functionality and specificity tested by ELISA prior to shipment.

• Suitable for in vitro research studies.

• No commercially available equivalent is available.

5. Quantity: One (1) lot consisting of 2.8 mg of AbD57571pao custom recombinant Fab antibody.

6. Delivery Date or Period of Performance: Delivery is required within approximately 5 to 7 weeks after receipt and acceptance of the order.

7. Option(s): None.

(vi) Delivery Location:

NIH/NCATS- 9808 Medical Center Drive, Rockville, MD 20850

(viii) FAR 52.204-7, System for Award Management, applies to this acquisition.

(ix) The provision at FAR 52.212-1, Instructions to Offerors—Commercial Items, applies to this acquisition. Add any agency-specific instructions as required.

(x) The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.

(a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation represents the best value to the Government, price and other factors considered.

(b) Evaluation Factors:

• Price

• Technical capability

• Past performance

• Delivery schedule

(c) A written notice of award or acceptance of an offer, issued within the time specified in the offer, shall result in a binding contract without further action by either party. The Government reserves the right to accept any offer before the expiration date.

(xi) FAR 52.212-4, Contract Terms and Conditions—Commercial Items, applies to this acquisition.

(xii) Additional contract requirements or terms and conditions, as determined necessary by the Contracting Officer and consistent with customary commercial practices: None

(xiii) The Defense Priorities and Allocations System (DPAS) is not applicable.

(xiv) Submission Requirements:

Responses must include sufficient information to demonstrate the offeror’s capability to provide the required product or service. Quotes shall include, at a minimum:

• Unit and total price

• Shipping and handling costs

• Delivery timeframe after award

• Delivery terms

• F.O.B. point (destination or origin)

• Product or catalog numbers (if applicable)

• Product/service description

Additional evaluation considerations may include past performance, warranty, lifecycle cost, maintenance availability, and environmental or energy efficiency.

Responses must include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by August 24, 8:00AM EST and must reference solicitation number 75N98026Q00977. Responses may be submitted electronically to Jaddua.Johnston@nih.gov

(xv) Point of Contact: Jaddua Johnston Contracting Specialist, Phone Number: 240-569-0006

Email: Jaddua.Johnston@nih.gov mailto:Jaddua.Johnston@nih.gov

Version 12-23-2025-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: The National Center for Advancing Translational

Sciences (NCATS) requires a custom HuCAL recombinant Fab antibody to support ongoing in vitro studies for the Therapeutics for Retinitis Pigmentosa PEDF project. Erik Wagner and the Drug Metabolism and Pharmacokinetics (DMPK) research team will use this antibody to generate data needed to evaluate potential therapies for Retinitis Pigmentosa. This specialized reagent is required to conduct planned experiments and support project objectives. Without this antibody, key studies may be delayed or unable to proceed, impacting project timelines and research progress. This requirement supports NCATS' mission to accelerate the development of treatments and interventions for human diseases.

2. Background Information and Project details: This requirement supports the TDB- RP_H105A-Becerra project, "Therapeutics for Retinitis Pigmentosa PEDF.” The project is focused on evaluating PEDF-related therapeutic approaches for Retinitis Pigmentosa.

The antibody was previously developed for a collaborator and is needed to support ongoing research activities and maintain continuity with existing experimental methods and data.

3. Generic Name of Product: Custom recombinant Fab antibody for in vitro research use.

4. Purchase Description and Salient Characteristics:

Trade Name/Brand: HuCAL Recombinant Fab-F-Spy2-H Antibody Manufacturer: Bio-Rad AbD Serotec GmbH Product/Clone: AbD57571pao (derived from clone AbD57571ad) Quantity Required: 2.8 mg

Salient Characteristics:

• Custom recombinant Fab antibody with DYKDDDDK, Spy2, and His-6 tags.

• Coupled Fab antibody format produced using SpyTag/SpyCatcher technology.

• Specific for a 17-amino-acid peptide derived from PEDF protein.

• Purified using affinity chromatography.

• Functionality and specificity tested by ELISA prior to shipment.

• Suitable for in vitro research studies.

• No commercially available equivalent is available.

5. Quantity: One (1) lot consisting of 2.8 mg of AbD57571pao custom recombinant Fab antibody.

6. Delivery Date or Period of Performance: Delivery is required within approximately 5 to 7 weeks after receipt and acceptance of the order.

7. Option(s): None.

Title