REQUEST FOR QUOTATION

(THIS IS NOT AN ORDER)

THIS RFQ IS IS NOT A SMALL BUSINESS SET-ASIDE

15. DATE OF QUOTATION

16. SIGNER

a. NAME (Type or print)

c. TITLE (Type or print)

b. TELEPHONE

AREA CODE

NUMBER

STANDARD FORM 18 (REV. 6/1995)

Prescribed by GSA-FAR (48 CFR) 53.215-1(a)

AUTHORIZED FOR LOCAL REPRODUCTION

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8. TO:

b. COMPANYa. NAME

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9. DESTINATION

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7. DELIVERY

FOB DESTINATION

OTHER

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10. PLEASE FURNISH QUOTATIONS TO THE

ISSUING OFFICE IN BLOCK 5a ON OR BEFORE CLOSE OF BUSINESS (Date)

IMPORTANT: This is a request for information and quotations furnished are not offers. If you are unable to quote, please so indicate on this form and return it to the address in Block 5a. This request does not commit the Government to pay any costs incurred in the preparation of the submission of this quotation or to contract for supplies or service. Supplies are of domestic origin unless otherwise indicated by quoter. Any representations and/or certifications attached to this Request for Quotation must be completed by the quoter.

11. SCHEDULE (Include applicable Federal, State and local taxes)

ITEM NUMBER

(a)

SUPPLIES/SERVICES

(b)

QUANTITY

(c)

UNIT

(d)

UNIT PRICE

(e)

AMOUNT

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12. DISCOUNT FOR PROMPT PAYMENT

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NUMBER PERCENTAGE

NOTE: Additional provisions and representations are are not attached.

13. NAME AND ADDRESS OF QUOTER

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14. SIGNATURE OF PERSON AUTHORIZED TO

SIGN QUOTATION

PAGE OF PAGES

1. REQUEST NUMBER 2. DATE ISSUED 3. REQUISITION/PURCHASE REQUEST NUMBER 4. CERT. FOR NAT. DEF.

UNDER BDSA REG. 2

AND/OR DMS REG. 1

RATING

5a. ISSUED BY 6. DELIVER BY (Date)

NAME TELEPHONE NUMBER

AREA CODE NUMBER

c. CITY

5b. FOR INFORMATION CALL (NO COLLECT CALLS)

National Institutes of Health OD - Office of Logistics and Acquisition Operations 6100 Executive Blvd., Room 6B05 Bethesda, MD 20892-7511

75N98026Q00849

CASSIE RUNNER

+13

014-808827

07/28/2026

08/04/2026 1400 ED

Multiple

The purpose of this NON-COMPETITIVE

COMBINED SYNOPSIS / SOLICITATION is to acquire Blackbox One BB1 1R-4 In Vivo

Behavioral Analysis System and

Palmreader Software

The following FAR clauses and Provisions are applicable to this award.

FAR 52.204-13 System for Award

Management Maintenance (Oct 2018)

FAR 52.204-18 Commercial and Government

Entity Code Maintenance (Aug 2020)

HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity

Investigations (Dec 2015)

Continued...

1 8

CONTINUATION SHEET

REFERENCE NO. OF DOCUMENT BEING CONTINUED PAGES

NAME OF OFFEROR OR CONTRACTOR

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(E)

AMOUNT

(F)

OPTIONAL FORM 336 (4-86)

Sponsored by GSA FAR (48 CFR) 53.110

ITEM NO.

(A)

QUANTITY

(C)

NSN 7540-01-152-8067

75N98026Q00849

FAR 52.212-4 Contract Terms and Conditions -In addition to all the applicable commercial

Products and Commercial Services (Nov 2023)

FAR 52.217-8 Option to Extend Services (Nov

1999)

FAR 52.252-2 CLAUSES INCORPORATED BY REFERENCE

NON-COMPETITIVE

COMBINED SYNOPSIS / SOLICITATION

Title: Acquire Blackbox One™ BB1 1R-4 In Vivo Behavioral Analysis System and Palmreader Software

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

(ii) The solicitation number is 75N98026Q00849. This solicitation is issued as a Notice of Intent (NOI) for a non-competitive combined synopsis/solicitation to award a contract or purchase order without providing for full and open competition.

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold. Additional authority includes 41 U.S.C. 1901 and FAR 6.302-3(a)(2)(ii).

The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a Firm-Fixed Price award on a non-competitive basis to Blackbox Biotech, Inc. 2801 Just in Road, Suite 210 Flower Mound, TX 75077 to acquire Blackbox One™ BB1 1R-4 In Vivo Behavioral Analysis System and Palmreader Software.

(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular, FAC 2026-01, March 2026.

(iv) NAICS Code: 334516: Analytical Laboratory Instrument Manufacturing the small business size standard is “1,000 employees”.

Set aside Status: This requirement is NOT set aside for small business.

(v) Description of Requirement:

• High-resolution behavioral analysis of freely moving mice and rats.

• Simultaneous assessment of ventral body pose and paw contact/force measurements.

• Compatibility with Palmreader data acquisition and analysis software.

• Access to proprietary behavioral metrics and reporting functions.

• Manufacturer-supported software updates and technical support.

• Ability to accommodate future customization for specialized research applications.

(vi) Delivery Location:

Dr. Nicholas Ryba

NIH/NIDCR

Building 35A, Room 3F220 35A Convent Dr. MSC 3757

Bethesda MD 20892

(vii) [Reserved, if needed]

(viii) The provision at FAR 52.212-1, Instructions to Offerors—Commercial Items, applies to this acquisition. Add any additional instructions as required.

(ix) The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.

(a) A written notice of award or acceptance of an offer, issued to the successful offeror within the time specified in the offer, shall result in a binding contract without further action by either party.

The Government reserves the right to accept any offer (or part of an offer) before the expiration date, whether or not discussions are conducted, unless a written notice of withdrawal is received prior to award. Add additional evaluation criteria as required.

(x) Offerors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Items, with their offer.

(xi) FAR 52.212-4, Contract Terms and Conditions—Commercial Items, applies to this acquisition.

(xii) FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders—Commercial Items, applies to this acquisition.

(xiii) Additional contract requirements or terms and conditions, as determined necessary by the Contracting Officer and consistent with customary commercial practices: None.

(xiv) The Defense Priorities and Allocations System (DPAS) is not applicable to this requirement.

(xv) Submission Requirements:

Responses must include sufficient information to demonstrate the respondent’s capability to provide the required product or service. Price quotations shall include, at a minimum: unit price, list price, shipping and handling costs, delivery timeframe after award, delivery terms, prompt payment discount terms, F.O.B. point (destination or origin), product or catalog numbers, product descriptions, and any other relevant information.

Evaluation factors may include, but are not limited to: past performance, technical capability, special features, trade-in considerations, expected lifecycle, warranty, maintenance availability, and environmental or energy efficiency considerations.

Respondents claiming to be manufacturers or authorized resellers of a specified brand-name product must provide:

(a) Product, catalog, model, and/or part number(s);

(b) Product description;

(c) Documentation demonstrating that the offered item meets all required salient characteristics;

(d) Quantity;

(e) Estimated price or cost;

(f) Shipping, handling, and/or installation charges; and

(g) Delivery timeframe after receipt of order.

Responses must also include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by August 3, 2026, and 2PM (1400) EST and must reference solicitation number 75N98026Q00849. Responses may be submitted electronically to cassie.runner@nih.gov.

(xvi) Point of Contact:

Cassie Runner, Contract Specialist, cassie.runner@nih.gov, 301-480-8827 mailto:cassie.runner@nih.gov

Statement of Need (SON)

To: Contracting Officer, Branch, Office of Acquisitions (OA), Office of Management, (OM), National Heart, Lung, and Blood Institute (NHLBI)

From: Project Manager (PM) Lars VonBuchholtz, NIDCR

Organization: NIDCR/DIR

Project Title: Blackbox One™ BB1 1R-4 In Vivo Behavioral Analysis System and Palmreader™ Software

1. Type of Statement of Need

Statement of Need - Equipment Statement of Need – License Agreement

Statement of Need – Supply/Product Statement of Need –Subscription Services

Statement of Need – Maintenance Service Statement of Need – Warranty Agreement

Statement of Need – Other

2. Technical Background and Contractual History 7.105 (a) (1)

This is a new requirement

This is a follow-on requirement

Technical Background:

Background for why you need it:

The purpose of this acquisition is to support preclinical research through advanced behavioral phenotyping of laboratory rodents. The Blackbox One™ BB1 1R-4 system is a specialized in vivo laboratory analytical instrument designed to characterize the behavior of freely moving laboratory mice and rats through simultaneous analysis of body pose and paw contact dynamics.

The Blackbox One system captures unique behavioral measurements by analyzing: (1) body pose as viewed from beneath the animal and (2) the contact points and force distribution of each paw. These measurements provide investigators with objective assessments of mammalian nervous system function and generate data that cannot be obtained through conventional behavioral testing systems.

The associated Palmreader™ software platform provides proprietary data acquisition, processing, visualization, and analysis capabilities required for operation of the Blackbox One instrument. Together, the hardware and software produce unique behavioral endpoints that have been demonstrated to identify pain states, evaluate analgesic efficacy, and distinguish analgesic effects from sedative effects in preclinical models.

The Blackbox One hardware and Palmreader™ software are protected by issued U.S. patents and international patent applications, including but not limited to U.S. Patent Publications US20190261596A1, US20180260645, and US20190080158, as well as international patent filings EP3349567, WO/2017/049249, CA2999136, EP3349566, CA2999114, IL258188, IL258187, IN201817014523, and

IN201817014522.

Contractual History N/A

3. Applicable Conditions 7.105 (a) (2)

Not Applicable

Brand Name Requirement (A brand name justification is attached)

Sole Source Requirement (A sole source justification is attached)

4. Compatibility or Performance Characteristics for Supply of Service 7.105 (a) (4)

Required Features & Benefits of the acquisition:

The Blackbox One™ BB1 1R-4 system provides specialized behavioral analysis capabilities required for ongoing and future research studies involving rodent models. The system offers proprietary technology that measures body pose and paw force dynamics simultaneously, generating behavioral datasets unavailable through alternative commercial systems.

Required components include:

Blackbox One™ BB1 1R-4 In Vivo Behavioral Analysis Instrument Palmreader™ Software Platform Associated proprietary hardware, firmware, data acquisition systems, and software licenses Technical support, software maintenance, and system customization services as required

Specifications needed:

• High-resolution behavioral analysis of freely moving mice and rats.

• Simultaneous assessment of ventral body pose and paw contact/force measurements.

• Compatibility with Palmreader™ data acquisition and analysis software.

• Access to proprietary behavioral metrics and reporting functions.

• Manufacturer-supported software updates and technical support.

• Ability to accommodate future customization for specialized research applications.

Other Considerations & Specifications:

• Contractor access to Government facilities may be required for equipment delivery, installation, testing, and training activities.

• Inspection/Acceptance: Equipment shall be considered accepted upon successful installation, system verification, software activation, and demonstration of operational functionality.

Compatibility/Performance Requirements:

The acquisition must provide:

• Full compatibility between instrument hardware and Palmreader™ software.

• Access to proprietary behavioral analysis algorithms and data formats.

• Manufacturer-authorized technical support and maintenance.

• Compliance with required data security, quality assurance, communication, and connectivity standards established by the manufacturer.

• Availability of customization services for specialized scientific applications.

5. Delivery or Performance-Period Requirements 7.105 (a) (5)

Period of Performance: N/A

Delivery Requirements:

Delivery, installation, software activation, and operational acceptance shall occur no later than 8/1/2026

The Blackbox One™ BB1 1R-4 system and Palmreader™ software are available exclusively from Blackbox

Biotech, Inc. Due to patent protections, proprietary hardware architecture, proprietary software requirements, unique components, and manufacturer-controlled support and customization services, no alternative manufacturer, reseller, or distributor can provide an equivalent system or satisfy delivery and performance requirements.

Title