REQUEST FOR QUOTATION

(THIS IS NOT AN ORDER)

THIS RFQ IS IS NOT A SMALL BUSINESS SET-ASIDE

15. DATE OF QUOTATION

16. SIGNER

a. NAME (Type or print)

c. TITLE (Type or print)

b. TELEPHONE

AREA CODE

NUMBER

STANDARD FORM 18 (REV. 6/1995)

Prescribed by GSA-FAR (48 CFR) 53.215-1(a)

AUTHORIZED FOR LOCAL REPRODUCTION

Previous edition not usable

8. TO:

b. COMPANYa. NAME

c. STREET ADDRESS

d. CITY e. STATE f. ZIP CODE

9. DESTINATION

a. NAME OF CONSIGNEE

b. STREET ADDRESS

d. STATE e. ZIP CODE

7. DELIVERY

FOB DESTINATION

OTHER

(See Schedule)

10. PLEASE FURNISH QUOTATIONS TO THE

ISSUING OFFICE IN BLOCK 5a ON OR BEFORE CLOSE OF BUSINESS (Date)

IMPORTANT: This is a request for information and quotations furnished are not offers. If you are unable to quote, please so indicate on this form and return it to the address in Block 5a. This request does not commit the Government to pay any costs incurred in the preparation of the submission of this quotation or to contract for supplies or service. Supplies are of domestic origin unless otherwise indicated by quoter. Any representations and/or certifications attached to this Request for Quotation must be completed by the quoter.

11. SCHEDULE (Include applicable Federal, State and local taxes)

ITEM NUMBER

(a)

SUPPLIES/SERVICES

(b)

QUANTITY

(c)

UNIT

(d)

UNIT PRICE

(e)

AMOUNT

(f)

12. DISCOUNT FOR PROMPT PAYMENT

a. 10 CALENDAR DAYS (%) b. 20 CALENDAR DAYS (%) c. 30 CALENDAR DAYS (%) d. CALENDAR DAYS

NUMBER PERCENTAGE

NOTE: Additional provisions and representations are are not attached.

13. NAME AND ADDRESS OF QUOTER

a. NAME OF QUOTER

b. STREET ADDRESS

c. COUNTY

d. CITY e. STATE f. ZIP CODE

14. SIGNATURE OF PERSON AUTHORIZED TO

SIGN QUOTATION

PAGE OF PAGES

1. REQUEST NUMBER 2. DATE ISSUED 3. REQUISITION/PURCHASE REQUEST NUMBER 4. CERT. FOR NAT. DEF.

UNDER BDSA REG. 2

AND/OR DMS REG. 1

RATING

5a. ISSUED BY 6. DELIVER BY (Date)

NAME TELEPHONE NUMBER

AREA CODE NUMBER

c. CITY

5b. FOR INFORMATION CALL (NO COLLECT CALLS)

National Institutes of Health OD - Office of Logistics and Acquisition Operations 6100 Executive Blvd., Room 6B05 Bethesda, MD 20892-7511

75N98026Q00640

JOHN JOHNSON

+10

000-000000

06/16/2026

06/26/2026 1600 ED

Multiple

The purpose of this COMPETITIVE COMBINED

SYNOPSIS / SOLICITATION is to acquire

Long Sequencing kits for NIH/NIMH.

The following FAR clauses and Provisions are applicable to this award.

FAR 52.204-13 System for Award

Management Maintenance (Oct 2018)

FAR 52.204-18 Commercial and Government

Entity Code Maintenance (Aug 2020)

HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity

Investigations (Dec 2015)

FAR 52.212-4 Contract Terms and

Conditions -In addition to all the

Continued...

1 2

CONTINUATION SHEET

REFERENCE NO. OF DOCUMENT BEING CONTINUED PAGES

NAME OF OFFEROR OR CONTRACTOR

SUPPLIES/SERVICES

(B)

UNIT

(D)

UNIT PRICE

(E)

AMOUNT

(F)

OPTIONAL FORM 336 (4-86)

Sponsored by GSA FAR (48 CFR) 53.110

ITEM NO.

(A)

QUANTITY

(C)

NSN 7540-01-152-8067

75N98026Q00640 applicable commercial Products and Commercial

Services (Nov 2023)

FAR 52.212-5 Contract Terms and Conditions

Required to Implement Statutes or Executive

Orders/Commercial Products and Commercial

Services (Jan 2025)

FAR 52.217-8 Option to Extend Services (Nov

1999)

FAR 52.217-9 Option to Extend the Term of the

Contract

FAR 52.252-2 CLAUSES INCORPORATED BY REFERENCE

COMBINED SYNOPSIS / SOLICITATION (COMPETITIVE)

Title: Long Sequencing kits

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

(ii) The solicitation number is 75N98026Q00640/PCA-NIA-01344. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services.

The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold (if applicable).

The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, seeks to award a firm fix-price contract to the responsible offeror whose proposal represents the best value to the Government.

(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition March 2026.

(iv) The associated NAICS code is 541713, and the small business size standard is other than small.

• This requirement is unrestricted.

(v) Description of Requirement:

Below is a table that contains the line item numbers and description of the brand name or equal requirement for the anticipated award.

Line No. Description 1 PromethION Flow Cells Packs DNA. QTY 65 2 Ligation Sequencing Kit XL V14. QTY 6 3 Sequencing Auxiliary Vials XL. QTY 6

(vi) Delivery Location:

NIH/NIA

251 Bayview Blvd STE 100

Baltimore MD 21224

(vii) [Reserved, if needed]

(viii) The provision at FAR 52.212-1, Instructions to Offerors—Commercial Items, applies to this acquisition. Add any agency-specific instructions as required.

(ix) The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.

(a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation represents the best value to the Government, price and other factors considered.

(b) Evaluation Factors:

• Price

• Technical capability

• Past performance

• Delivery schedule

(c) A written notice of award or acceptance of an offer, issued within the time specified in the offer, shall result in a binding contract without further action by either party. The Government reserves the right to accept any offer before the expiration date.

(x) Offerors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Items, with their offer.

(xi) FAR 52.212-4, Contract Terms and Conditions—Commercial Items, applies to this acquisition.

(xii) FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders—Commercial Items, applies to this acquisition.

(xiii) Additional contract requirements or terms and conditions, as determined necessary by the Contracting Officer and consistent with customary commercial practices:

(None)

(xiv) The Defense Priorities and Allocations System (DPAS) is not applicable.

(xv) Submission Requirements:

Responses must include sufficient information to demonstrate the offeror’s capability to provide the required product or service. Quotes shall include, at a minimum:

• Unit and total price

• Shipping and handling costs

• Delivery timeframe after award

• Delivery terms

• F.O.B. point (destination or origin)

• Product or catalog numbers

• Product description

Additional evaluation considerations may include past performance, warranty, lifecycle cost, maintenance availability, and environmental or energy efficiency.

Responses must include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by (June 26, 2026, 2PM EST) and must reference solicitation number 75N98026Q00640/PCA-NIA-01344. Responses may be submitted electronically to johnsonjr@mail.nih.gov

(xvi) Point of Contact:

John Johnson, Program Specialist, 667-312-5580, and johnsonjr@mail.nih.gov mailto:johnsonjr@mail.nih.gov mailto:johnsonjr@mail.nih.gov

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: The purpose of this acquisition is to provide supplies to the Center for Alzheimer’s Disease and Related Dementias for neurodegenerative disease research for the purpose of long read sequencing on Oxford Nanopore manufactured sequencing systems. These reagents will be used to identify causative genes for neurodegenerative diseases.

2. Background Information and Objective:

The National Institute on Aging’s Center for Alzheimer’s Disease and Related Dementias (CARD) is continuing the 2024 initiative investigating Posterior Cortical Atrophy (PCA).

CARD is expanding focus on two key brain regions based on our previous pathological investigations, the superior temporal and superior parietal cortices from 40 PCA and age-matched 40 amnestic Alzheimer’s Disease cases to identify molecular and cellular differences that underpin the distinct pathological features of these phenotypes. This initiative will continue to generate long-read sequencing and methylation profiles, as well as single-cell transcriptomic data, to provide insights into the genetic, epigenetic, and transcriptional changes in these regions. Additionally, CARD aims to include samples from age-matched normal controls (n=20) as a baseline to further elucidate region-specific and disease-specific changes in PCA and amnestic Alzheimer’s Disease.

3. Generic Name of Product: Long Sequencing kits

4. Purchase Description:

Contract Line Item Description Catalogue Number Quantity

PromethION Flow Cells Packs DNA FLO-PRO114M 65.00 Ligation Sequencing Kit XL V14 SQK-LSK114-XL 6.00 Sequencing Auxiliary Vials XL EXP-AUX003-XL 6.00

5. Salient characteristics All deliverables required under this contract shall be packaged, marked and shipped in accordance with Government specifications. At a minimum, all deliverables shall be marked with the contract number and Contractor name. The Contractor shall guarantee that all required materials shall be delivered in immediate usable and acceptable condition.

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

Ligation Sequencing Kit salient characteristics:

Must require no more than 1 µg of gDNA or 100-200 fmol of amplicons or cDNA as starting material.

Must provide for 6 reactions

Sequencing Auxiliary Vials salient characteristics:

Must contain sequencing buffer, elution buffer, library solution, library beads, with V14 flow cell priming reagents: flow cell flush and flow cell tether.

Must provide for 12 reactions

Flow Cell Wash Kit salient characteristics:

Must provide reagents required to wash and reuse MinION™ and PromethION™ Flow Cells

Must provide for 48 reactions

Flow Cell salient characteristics:

Must be able to generate consensus data at a modal accuracy above 99%

Must be compatible with Nanopore PromethION 48 sequencers in form, fit, and function

6. Quantity:

Contract Line Item Description Catalogue Number Quantity

PromethION Flow Cells Packs DNA FLO-PRO114M 65.00 Ligation Sequencing Kit XL V14 SQK-LSK114-XL 6.00 Sequencing Auxiliary Vials XL EXP-AUX003-XL 6.00

7. Period of Performance: Not applicable.

8. Option(s): Not applicable.

Title