Sol_75N98026Q00421.pdf

REQUEST FOR QUOTATION

(THIS IS NOT AN ORDER)

THIS RFQ IS IS NOT A SMALL BUSINESS SET-ASIDE

15. DATE OF QUOTATION

16. SIGNER

a. NAME (Type or print)

c. TITLE (Type or print)

b. TELEPHONE

AREA CODE

NUMBER

STANDARD FORM 18 (REV. 6/1995)

Prescribed by GSA-FAR (48 CFR) 53.215-1(a)

AUTHORIZED FOR LOCAL REPRODUCTION

Previous edition not usable

8. TO:

b. COMPANYa. NAME

c. STREET ADDRESS

d. CITY e. STATE f. ZIP CODE

9. DESTINATION

a. NAME OF CONSIGNEE

b. STREET ADDRESS

d. STATE e. ZIP CODE

7. DELIVERY

FOB DESTINATION

OTHER

(See Schedule)

10. PLEASE FURNISH QUOTATIONS TO THE

ISSUING OFFICE IN BLOCK 5a ON OR BEFORE CLOSE OF BUSINESS (Date)

IMPORTANT: This is a request for information and quotations furnished are not offers. If you are unable to quote, please so indicate on this form and return it to the address in Block 5a. This request does not commit the Government to pay any costs incurred in the preparation of the submission of this quotation or to contract for supplies or service. Supplies are of domestic origin unless otherwise indicated by quoter. Any representations and/or certifications attached to this Request for Quotation must be completed by the quoter.

11. SCHEDULE (Include applicable Federal, State and local taxes)

ITEM NUMBER

(a)

SUPPLIES/SERVICES

(b)

QUANTITY

(c)

UNIT

(d)

UNIT PRICE

(e)

AMOUNT

(f)

12. DISCOUNT FOR PROMPT PAYMENT

a. 10 CALENDAR DAYS (%) b. 20 CALENDAR DAYS (%) c. 30 CALENDAR DAYS (%) d. CALENDAR DAYS

NUMBER PERCENTAGE

NOTE: Additional provisions and representations are are not attached.

13. NAME AND ADDRESS OF QUOTER

a. NAME OF QUOTER

b. STREET ADDRESS

c. COUNTY

d. CITY e. STATE f. ZIP CODE

14. SIGNATURE OF PERSON AUTHORIZED TO

SIGN QUOTATION

PAGE OF PAGES

1. REQUEST NUMBER 2. DATE ISSUED 3. REQUISITION/PURCHASE REQUEST NUMBER 4. CERT. FOR NAT. DEF.

UNDER BDSA REG. 2

AND/OR DMS REG. 1

RATING

5a. ISSUED BY 6. DELIVER BY (Date)

NAME TELEPHONE NUMBER

AREA CODE NUMBER

c. CITY

5b. FOR INFORMATION CALL (NO COLLECT CALLS)

National Institutes of Health OD - Office of Logistics and Acquisition Operations 6100 Executive Blvd., Room 6B05 Bethesda, MD 20892-7511

75N98026Q00421

JADDUA JOHNSTON

+10

000-000000

05/21/2026

06/05/2026 1800 ED

Multiple

The purpose of this COMBINED SYNOPSIS /

SOLICITATION (COMPETITIVE) is acquire five (5) replacement Teledyne ISCO

CombiFlash NextGen 300+ Automated Flash

Chromatography Systems to replace existing CombiFlash Rf+ and Rf+ Lumen instruments currently in use within

NCATS chemistry laboratories.

Period of Performance: 06/08/2026 to

08/08/2026

This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the contracting officer will make their full

Continued...

1 10

CONTINUATION SHEET

REFERENCE NO. OF DOCUMENT BEING CONTINUED PAGES

NAME OF OFFEROR OR CONTRACTOR

SUPPLIES/SERVICES

(B)

UNIT

(D)

UNIT PRICE

(E)

AMOUNT

(F)

OPTIONAL FORM 336 (4-86)

Sponsored by GSA FAR (48 CFR) 53.110

ITEM NO.

(A)

QUANTITY

(C)

NSN 7540-01-152-8067

text available. Also, the full text of a clause may be accessed electronically at this address:

HTTPS://ACQUISITION.GOV/FAR

The following FAR clauses and Provisions are applicable to this award.

FAR 52.204-13 System for Award Management

Maintenance (Oct 2018);

FAR 52.204-18 Commercial and Government Entity

Code Maintenance (Aug 2020);

HHSAR 352.222-70, Contractor Cooperation in

Equal Employment Opportunity Investigations

(Dec 2015).

FAR 52.212-4 Contract Terms and Conditions -In addition to all the applicable commercial

Products and Commercial Services (Nov 2023)

FAR 52.212-5 Contract Terms and Conditions

Required to Implement Statutes or Executive

Orders/Commercial Products and Commercial

Services (Jan 2025)

FAR 52.252-2 CLAUSES INCORPORATED BY REFERENCE

Award enclosure:

Quote

IPP Invoicing and Payment Provisions

To avoid delay in payment, all invoices must be uploaded into the invoicing processing platform

(IPP) (https://www.ipp.gov). The invoice must match the line item description on the purchase order. It must also state that payment is to be made using a three-way match.

You are reminded that only the contracting officer of record can make any changes to this award any changes made at the direction of the program without¿an executed modification and

Continued...

CONTINUATION SHEET

REFERENCE NO. OF DOCUMENT BEING CONTINUED PAGES

NAME OF OFFEROR OR CONTRACTOR

SUPPLIES/SERVICES

(B)

UNIT

(D)

UNIT PRICE

(E)

AMOUNT

(F)

OPTIONAL FORM 336 (4-86)

Sponsored by GSA FAR (48 CFR) 53.110

ITEM NO.

(A)

QUANTITY

(C)

NSN 7540-01-152-8067

null and void and are done at the contractor's own risk.

COMBINED SYNOPSIS / SOLICITATION (COMPETITIVE)

Title: Replacement of CombiFlash Chromatography Systems

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

(ii) The solicitation number is 75N98026Q00421. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services. The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold.

The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, seeks to award a firm-fixed-price purchase order to the responsible offeror whose proposal represents the best value to the Government.

(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01, effective March 13, 2026.

(iv) The associated NAICS code is 334516– Analytical Laboratory Instrument Manufacturing, and the small business size standard is 1000 employees.

This requirement is unrestricted.

(v) Description of Requirement:

The Government is conducting market research to identify vendors capable of providing all of the following:

1. Five (5) replacement CombiFlash NextGen 300+ Liquid Chromatography Systems

2. Five (5) Adjustable Solid Load Cartridge Cap

3. Two (2) of the five systems should also have Evaporative Light Scattering Detector (ELSD)

Units

4. Vendor should be able to complete delivery within 60 days

5. Trade-In 5 obsolete CombiFlash systems

6. Shipping and installation of all new CombiFlash NextGen 300+ systems and accessories

Minimum Requirements:

Five (5) Total Teledyne ISCO CombiFlash NextGen 300+ with Adjustable Solid Load Cartridge Cap Two (2) of the 5 Total should have ELSD (Evaporative Light Scattering Detector) units Installation of all units at NCATS, see Place of Performance/Delivery below.

1. Five (5) Part # 685250001: CombiFlash NextGen 300+ Automated Flash Chromatography System

a. UV detector 200-400 nm with PeakTrak software control via 12" capacitive touchscreen.

Flow rate range of 1-300mL/min. Maximum pressure limit of 300psi (20bar)

b. Automated solid load injection valve. RFID rack and column read. Automatically loads column method information and writes back run information to the column. Automatically loads rack configuration. Active solvent level sensing.

c. One set of collection racks (quantity 2):

i. ----- 117V - (140) 18x150mm test tubes (Standard)

ii. -----234V - (150) 16x150mm test tubes (Standard)

2. Five (5) Part # 605237048: Adjustable Solid Load Cartridge Cap (SLCC)

a. fits 12 and 25 gram-size sample load cartridges includes one loading rod. Compatible with the NextGen system. Optional accessory for NextGen system.

3. Two (2) Part # 605257001: ELSD for CombiFlash NextGen 300+.

a. To be installed on two of the above referenced units when ordered with the NextGen.

Installation cost to be added for field installations.

4. Five (5) Part # CHROM INSTAL SALES:

a. "CHROMINSTALSALES" - Installation for Teledyne Isco CombiFlash. Products in US territories.

(vi) Delivery Location:

NCATS

9800 Medical Center Drive, Building C, 210W Rockville MD 20850

(vii) [Reserved, if needed]

(viii) The provision at FAR 52.212-1, Instructions to Offerors—Commercial Items, applies to this acquisition.

(ix) The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.

a) The Government intends to award a firm-fixed-price purchase order resulting from this combined synopsis/solicitation to the responsible vendor whose quotation:

• Meets the salient characteristics and requirements of this solicitation; and

• Represents the lowest total evaluated price to the Government.

The Government will evaluate quotations for technical acceptability and price.

(c) A written notice of award or acceptance of an offer, issued within the time specified in the offer, shall result in a binding contract without further action by either party. The Government reserves the right to accept any offer before the expiration date.

(x) Offerors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Items, with their offer.

(xi) FAR 52.212-4, Contract Terms and Conditions—Commercial Items, applies to this acquisition.

(xii) FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders—Commercial Items, applies to this acquisition.

(xiii) Additional contract requirements or terms and conditions, as determined necessary by the Contracting Officer and consistent with customary commercial practices: None

(xiv) The Defense Priorities and Allocations System (DPAS) is not applicable.

(xv) Submission Requirements:

Responses must include sufficient information to demonstrate the offeror’s capability to provide the required product or service. Quotes shall include, at a minimum:

• Unit and total price

• Shipping and handling costs

• Delivery timeframe after award

• Delivery terms

• F.O.B. point (destination or origin)

• Product or catalog numbers (if applicable)

• Product/service description

Additional evaluation considerations may include past performance, warranty, lifecycle cost, maintenance availability, and environmental or energy efficiency.

Responses must include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by 6/5/2026 @ 4:00 PM EDT and must reference solicitation number 75N98026Q00421. Responses may be submitted electronically to jaddua.johnston@nih.gov.

mailto:jaddua.johnston@nih.gov

Version 12-23-2025-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: The purpose of this procurement is to acquire five (5) replacement Teledyne ISCO CombiFlash NextGen 300+ Automated Flash Chromatography Systems to replace existing CombiFlash Rf+ and Rf+ Lumen instruments currently in use within NCATS chemistry laboratories.

The existing instruments are over 12 years old, obsolete, and no longer supported by the manufacturer, resulting in increased downtime and risk to ongoing research operations.

Two of the current systems are already inoperable. Replacement of these systems is necessary to restore full operational capacity, maintain continuity of laboratory workflows, and ensure reliable chromatographic purification capabilities for NCATS research activities.

2. Background Information and Project details: The existing CombiFlash systems support routine purification workflows critical to multiple NCATS research programs.

These instruments have exceeded their useful life and are increasingly unreliable due to age-related failures and lack of manufacturer support.

As of July 1, 2025, Teledyne ISCO discontinued on-site and depot service for all Rf+ and Rf+ Lumen instruments. The manufacturer has confirmed that only limited phone-based troubleshooting is available, replacement parts must be installed by the user, and certain legacy components are no longer available. This lack of serviceability presents a significant risk of extended downtime or permanent loss of functionality.

Replacement with current-generation systems is required to ensure continued supportability, maintain operational efficiency, and minimize disruption to existing workflows. Transitioning to a different manufacturer would require significant method redevelopment, validation, and staff retraining, which would adversely impact ongoing research timelines.

3. Generic Name of Product: Automated flash chromatography system

4. Purchase Description and Salient Characteristics:

The Government requires five (5) automated flash chromatography systems, brand name or equal to Teledyne ISCO CombiFlash NextGen 300+, that meet or exceed the following salient characteristics:

Functional Requirements:

• Fully automated flash chromatography system capable of routine purification of chemical compounds

• Integrated system control interface (touchscreen or equivalent) with software for method development, automation, and data collection

• Flow rate capability within the approximate range of 1–300 mL/min

• Operating pressure capability of approximately 300 psi (20 bar) or greater

• Automated sample loading capability (e.g., solid or liquid injection)

Detection and Monitoring:

• Integrated UV detection capability within approximately 200–400 nm range

• Ability to detect and monitor compounds lacking UV activity (e.g., via ELSD or equivalent technology) for at least two (2) systems

• Real-time monitoring and data collection during runs

Automation and Efficiency Features:

• Automated recognition of columns, racks, or equivalent system components

• Capability to automatically load, store, and apply methods

• Ability to track run data and associate it with specific separations

• Automated or assisted solvent monitoring to prevent run interruptions

Performance Requirements:

• Reproducible purification performance suitable for research laboratory use

• Compatibility with standard flash chromatography columns and consumables

• Capability to support high-throughput laboratory workflows

System Components and Accessories:

• Collection systems compatible with standard laboratory tubes or vessels

• Required accessories for sample loading and operation (e.g., cartridges, tubing, connectors)

• All components necessary for full system functionality at time of delivery

Installation and Support:

• Delivery, installation, and system setup included

• Warranty and technical support provided

• User training or orientation sufficient for laboratory personnel

4. Quantity:

Five (5) Automated Flash Chromatography Systems

• Including detection capability for non-UV active compounds on at least two (2) systems

• Including all required accessories and components

5. Delivery Date or Period of Performance:

Delivery and installation shall occur within 30–60 days after receipt of order at:

National Center for Advancing Translational Sciences (NCATS) 9800 Medical Center Drive Rockville, MD 20850

6. Option(s): None

Title