Sol_75N95D27Q00001.pdf

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National Institutes of Health OD - Office of Logistics and Acquisition Operations 6100 Executive Blvd., Room 6B05 Bethesda, MD 20892-7511

75N95D27Q00001

BRITTANY MAY

+10

000-000000

10/27/2026

11/06/2026 1730 ES

Multiple

PCA-NIA-06840

The purpose of this Competitive Combined

Synopsis/Solicitation is to procure

Automated high-throughput proteomics analysis system

1 1

07/18

NON-COMPETITIVE COMBINED SYNOPSIS/SOLICITATION

INTRODUCTION

This is a non competitive combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

The solicitation number is 75N95D27Q00001. This solicitation is issued as a non-competitive combined synopsis/solicitation for commercial products or commercial services. The Government intends to award a contract or purchase order without providing for full and open competition (Including Brand-Name).

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold.

The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a Firm-Fixed Price Purchase Order on a non-competitive basis to Alamar Biosciences for one (1) Automated high-throughput proteomics analysis system.

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under NAICS code 334516 - Analytical Laboratory Instrument Manufacturing with a Size Standard of 1000.

REGULATORY AUTHORITY

The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2026-01 effective March 13, 2026.

• This requirement is unrestricted

DESCRIPTION OF REQUIREMENT

The NIH Intramural Center for Alzheimer’s Disease and Related Dementias is an interdisciplinary initiative that is dedicated to advancing our understanding and treatment of Alzheimer’s disease and related dementias (AD/ADRD). Biomarkers play a critical role in understanding, diagnosing, and monitoring disease progression and therapeutic efficacy. We aim to identify biomarkers which will provide information about underlying molecular changes associated with AD/ADRD in well characterized samples from patients.

An automated high-throughput proteomics analysis system will provide ability to identify biomarkers which will provide information about underlying molecular changes associated with Alzheimer’s Disease and Related Dementias in well characterized samples from patients.

SALIENT CHARACTERISTICS

The automated high-throughput proteomics analysis system meet the following salient characteristics:

• Must provide a fully automated, high-throughput proteomics platform capable of processing up to 288 samples per run

• Must provide an integrated qPCR system enabling end-to-end workflow from sample preparation to data output or pooled NGS library generation

• Must provide a total hands-on time of less than 30 minutes with simplified workflow and <5-minute instrument setup

• Must provide results in <6 hours for singleplex assays and <15 hours for multiplex \325/

• Must]’

• provide cartridge-based reagent system capable of supporting up to three consecutive runs without replacement

• Must provide liquid handling system for automated sample preparation for both qPCR and NGS workflows

• Must provide integrated onboard computing with intuitive user interface for streamlined operation and workflow management

• [=Must provide a built-in cloud-based primary analysis software (ARGO Command Center) and secondary analysis software (NULISA Analysis Software, NAS)

• Must provide capability to transform raw data into biological insights and publication-ready results through integrated data analysis tools

• Must provide compatibility with ultra-high sensitivity NULISA™ assay technology enabling attomolar-level detection of protein biomarkers

• Must provide scalable multiplexing capability supporting singleplex to high-plex (100s–1000s of targets) biomarker analysis

• Must provide broad sample compatibility including plasma, serum, cerebrospinal fluid (CSF), urine, and cell culture media

• Must provide an application programming interface (API) available for custom method development and instrument control

• Must provide compliance with major regulatory and safety standards including EMC, UL, CE, WEEE, ISO 13485, and ISO 9001

• Must provide operating conditions supporting 15–24°C temperature range and 40– 80% non-condensing humidity

• Must provide electrical compatibility with 100–240 V power supply, 50–60 Hz, and maximum power consumption of 1500 watts

• Must provide instrument footprint no larger than 1143 mm (W) × 661 mm (D) × 1016 mm (H) and weight no heavier than 250 kg

CONTRACTOR REQUIREMENTS

Contractor shall provide the following:

ITEM

NO.

SCHEDULE OF SERVICES QUANTITY UNIT UNIT PRICE TOTAL AMT

0001 High Throughput Automated Proteomics Analysis System and all associated software and accessories

1 EA $ $

0002 Installation and all required Installation Materials and Services

1 EA $ $

0003 White Glove Services: includes freight, handling fees, and insurance and other services included

1 EA

0004 On Site Training for Instrument and Software: Including all Training Materials

1 EA $ $

TOTAL: $

EXPIRATION DATE OF QUOTE:

DELIVERY LOCATION

National Institutes of Health 9000 Rockville Pike Bldg T44 Bethesda, MD, 20892

The provision at FAR 52.212-1, Instructions to Offerors—Commercial Items, applies to this acquisition. Add any agency-specific instructions as required.

The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.

The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation represents the best value to the Government, price and other factors considered.

Evaluation Factors: (Customize as needed)

• Price

• Technical capability

• Past performance

• Delivery schedule (Include relative importance of factors if required.)

A written notice of award or acceptance of an offer, issued within the time specified in the offer, shall result in a binding contract without further action by either party. The Government reserves the right to accept any offer before the expiration date.

Offerors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Items, with their offer.

FAR 52.212-4, Contract Terms and Conditions—Commercial Items, applies to this acquisition.

Additional contract requirements or terms and conditions, as determined necessary by the Contracting Officer and consistent with customary commercial practices: None

The Defense Priorities and Allocations System (DPAS) is not applicable.

SUBMISSION REQUIREMENTS

This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this synopsis must include sufficient information to demonstrate the offeror’s bona-fide capabilities for fulfilling the required product or service. Responses must include, at a minimum:

• Unit and total price

• Shipping and handling costs

• Delivery period after award

• Delivery terms

• F.O.B. point (destination or origin)

• Product or catalog numbers (if applicable)

• Product/service description

Additional evaluation considerations may include past performance, warranty, lifecycle cost, maintenance availability, and environmental or energy efficiency.

Responses must include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by November 6, 2026, 5:30 PM EDT, and must reference solicitation number 75N95D27Q00001. Responses must be submitted via the SAM.gov webportal. Potential Offerors do not need to register to view a notice;

however, in order to submit questions and/or response to this Notice, an account will need to be established.

POINT OF CONTACT:

Brittany May Contract Specialist Brittany.May@nih.gov http://www.sam.gov/

Title