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SOURCES SOUGHT NOTICE

1. Solicitation Number: 75N95023Q00443

2. Title: KAPA Pure Beads

3. Classification Code: 6505- Drugs and Biologicals

4. NAICS Code: 334516 Analytical Laboratory Manufacturing Instrument

5. Size Standard: 1,000 employees

6. Description:

This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations.

The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualif ied small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition; and (4) availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of a satisfactory quality.

For equipment/supply requirements, small business responses must include: (1) the place of manufacturing (i.e. address if supply/equipment is a domestic end product and include country of manufacture), as well as (2) the size status of the manufacturer under the applicable NAICS code (i.e. address Non-Manufacturer Rule).

Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice.

This notice is issued to help determine the availability of qualif ied companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the

Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only.

Background:

The National Institutes of Health (NIH) is the nation’s leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge. The mission of the NIH also includes enhancing health, lengthening life, reducing illness and disability, conducting, supporting and making medical discoveries that improves and saves people’s health and lives.

The National Center for Advancing Translational Sciences (NCATS) is a part of the NIH, with a mission to catalyze the generation of innovative methods and technologies that will enhance the development, testing, and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions.

The NCATS Early Translation Branch (ETB) collaborates with investigators at NIH and in the academic, biopharmaceutical and nonprofit sectors to generate probes for studying a diverse cross-section of human biology, focusing specifically on new targets and untreatable diseases. The project team is collaboratively developing a high-throughput screening assay that assesses chromatin accessibility. This requisition is to procure DNA purif ication and size selection reagent that can be used in a novel screening assay. The experimental procedure has been optimized for use with the requested KAPA Pure Beads.

The collaborative team aims to develop a high-throughput chromatin assay. The reagent has been used in the optimization phase of the protocol and this purchase will provide material for high-throughput screening.

Purpose and Objectives: The purpose of this requirement is to procure thirty

(30) KAPA Pure Beads, a reagent needed for the amplif ication of DNA for next generation sequencing in high-throughput assay for chromatin. Configured for the Early Translation Branch (ETB) at the National Center for Advancing Translational Sciences (NCATS).

Project Requirements:

Purchase Description:

60 mL product size (07983298001), quantity of 30

1. Salient Characteristics

KAPA Pure Beads offer a tunable and highly consistent solution for reaction purif ication and size selection in DNA and RNA next-generation sequencing (NGS) library construction workflows. These feature high recovery of DNA in a single cleanup step, remove unwanted reaction components, and have adjustable size selection features

2. Other Requirements

The Contractor shall provide an Original Equipment Manufacturer (OEM) certified service technician to perform setup and installation for staff members.

Warranty - The Contractor shall warrant that the system will be free from defects for a period of at least 2 years from the date of installation, inspection by the Government, and acceptance. The Contractor shall further warrant that all components will be free from defects for a period of at least 2 years from the date of installation, inspection by the Government and acceptance. Warranty service shall include trouble-shooting capabilities based on complete knowledge of the entire system. A rapid response (within one business day) to service requests is required. The Contractor shall demonstrate that it is capable of providing this level and speed of service. Warranty shall not include routine or periodic maintenance services.

Contract Type and / Delivery Date: The Government anticipates awarding one (1) firm fixed-price purchase order under a future solicitation. The anticipated delivery date including installation and training seven (7) days after receipt of order (ARO).

The Contractor shall deliver and install the equipment to the NIH Delivery Address in Rockville, Maryland within 90 days after receipt of order (ARO). The equipment shall be delivered and installed between the hours of 8:00am and 5:00pm EST, Monday through Friday. Delivery must be Freight on Board (FOB) Destination and include inside delivery.

The equipment shall be delivered and installed in coordination with the NCATS personal [to be named at time of award] at the time the equipment is ready to be shipped.

The Contractor shall provide on-site training within 30 days of equipment installation.

The Contractor shall deliver, install, and provide training on the system within 42 days after receipt of order (ARO).

Delivery Address:

NIH National Center for Advancing Translational Sciences (NCATS) 9800 Medical Center Drive, Bldg C, Chemistry Lab Rockville, MD 20850

In case domestic sources are available and capable of fulf illing the Government’s need, and a future solicitation is published, the Government will use evaluation preferences in accordance with FAR 25.

Capability statement /information sought: Respondents must provide clear and convincing documentation of their capability of providing the products specified in this sources sought notice.

Moreover, interested vendors must provide a capability statement for:

• the diff iculty and/or feasibility of the potential requirement or proposed acquisition, possible solutions and approaches that may currently exist in the marketplace, and information regarding innovative ideas or concepts; and

• information regarding respondents’: (a) staff expertise, including their availability, experience, and formal and other training; (b) current in-house capability and capacity to perform the work; (c) prior completed projects of similar nature; (d) corporate experience and management capability; and (e) examples of prior completed Government contracts, references, and other related information.

• written capability statements should demonstrate organization’s capability to provide the brand-name or equal items listed in the Project Requirements section above. If the entity believes to be an authorized resellers of the brand-name product specified in this announcement or it desires to offer an equal product, the entity’s capability statement must include: (a) product, catalog, model, and/or part number(s); (b) product description;

(c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the Project Requirements section above; and country of manufacture of the product.

The respondent must also provide their DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements.

Submission Instructions:

One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2” x 11” paper size, with 1” top, bottom, left and right margins, and with single or double spacing.

The information submitted must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required.

The response is limited to ten (10) page limit. The 10-page limit does not include the cover page, executive summary, or references, if requested.

The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses.

All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted.

Responses must be received by 9:00 a.m., Eastern Time, on July 21, 2023, and reference Sources Sought Number 75N95023Q00443. Responses must be submitted by email to Chandani Hangilipola, Contract Specialist, chandani.hangilipola@nih.gov

“Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work.

Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).”