RFQ - NHGRI - 03621.docx

Request for Quotes Solicitation ID: RFQ-PCA-NHGRI-03621 Rotations for Medical Genetics and Genomic Medicine Residency and Fellowship Training Programs

This notice is a combined synopsis/solicitation for commercial items using Simplified Acquisition Procedures. This acquisition will be made in accordance with the format in Federal Acquisition Regulation (FAR) Subpart 12.6 “Streamlined Procedures for Evaluation and Solicitation for Commercial Items,” as applicable, and as supplemented with additional information included in this notice. This announcement constitutes the only solicitation (a written solicitation will not be issued) and quotes are being requested. The Solicitation number is RFQ-PCA-NHGRI-03621 and the solicitation is issued as a Request for Quotes (RFQ).

This acquisition will be processed under FAR Part 13 Simplified Acquisition Procedures (SAP). The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2024-05 May 22, 2024.

The North American Industry Classification System (NAICS) code for this procurement is 611310, Colleges, Universities and Professional Schools $34.5 Million.

The government intends to award a firm-fixed-price purchase order to the offeror responsible as a result of this RFQ that will include the terms and conditions set forth herein. By submitting a quote, the offeror is accepting that all government terms and conditions shall prevail over the award.

By submission of a quote, the Offeror acknowledges the requirement that a prospective awardee shall be registered and viewable in the System for Award Management (SAM) database prior to award, during performance, and through final payment resulting from this solicitation (www.sam.gov).

STATEMENT OF NEED

The purpose of this requirement is to maintain formal training program sites for the instruction of fellows as part of the requirements for board certification in Laboratory Genetics and Genomics. Division of Intramural Research (DIR) was established to serve as a hub where development of technology for the rapid isolation and analysis of disease genes will be carried out. The DIR’s basic research laboratories and clinical branches develop and use the most advanced techniques to conduct research in medical genetics. Research includes identifying and understanding the molecular basis of human genetic disease and planning and carrying out clinical trials to test methods for the treatment.

The mission of the DIR includes the training of physicians and doctoral degree fellows in medical genetics through the Medical Genetics and Genomic Medicine Training Programs. These programs are administered by the Office of the Clinical Director (OCD) and is accredited by the Accreditation Council for Graduate Medical Education (ACGME).

Requirements for board certification of competency of our trainees include broad exposure to and experience with pediatric and adult genetic disorders, including metabolic and mitochondrial disorders, complex traits, skeletal dysplasia’s, clefting, phacomatoses, and chromosomal disorders. The training must include information on the diagnosis and management of these disorders, including the opportunity to rotate in CLIA approved diagnostic genetic laboratories run by American Board of Medical Genetics (ABMG) certified staff. Another component must be the follow up of abnormal newborn screening results. Residents spend two of the 5 years training in Pediatrics at Children’s National Hospital, a world-renowned institution in metropolitan Washington, D.C. The pediatrics training is based in a diverse, urban setting and includes training experiences in the surrounding capital region. The curriculum includes rotations in subspecialty pediatrics, PICU, NICU, emergency medicine, well baby nursery, as well as inpatient and outpatient general pediatrics. Graduates are eligible to sit for the ABP board examination and well equipped to work in primary care and pediatric subspecialties.

To meet these requirements the Medical Genetics Branch and OCD seek nearby institutions to provide these components of training for board certification in Clinical Genetics, Clinical Biochemical Genetics, Medical Biochemical Genetics, Clinical Molecular Genetics and Clinical Cytogenetics. The staff, which must include both ACGME board certified geneticist(s) and a genetic counselor, will be required to train fellows in the approach, diagnosis, and management of various genetic disorders. In addition, trainees need to have training in applicable laboratory techniques and the clinical interpretation and implications of the test results. The staff must also participate in the comprehensive teaching of residents, including participation in lecture series, journal clubs, and case conferences. A genetic counselor will assist in the training of fellows in the interpretation and genetic implication of tests they are learning to perform in these diagnostic laboratories. Residents spend two of the 5 years training in Pediatrics at Children’s National Hospital, a world-renowned institution in metropolitan Washington, D.C. The pediatrics training is based in a diverse, urban setting and includes training experiences in the surrounding capital region. The curriculum includes rotations in subspecialty pediatrics, PICU, NICU, emergency medicine, well baby nursery, as well as inpatient and outpatient general pediatrics. Residents also spend 2 years completing requirements of a Medical Genetics residency at NHGRI/NIH which includes 18 months of clinical/laboratory rotations and 6 months of genetics-focused research. Clinical genetics rotations expose residents to inpatient and outpatient general genetics (adult and pediatric), cancer genetics, prenatal genetics, metabolism, and specialty genetics, and laboratory genetics rotations focus on molecular genetics, cytogenetics, and biochemical genetics. Rotations occur within NIH as well as at numerous institutions across the DMV region and offer exposure to common genetic conditions as well as unique rare diagnoses seen at NIH. The fifth and final year of training can either be used for research or subspecialty genetics training. Graduates are eligible to sit for board examinations by both ABP and ABMGG.

The goal of the program is to:

1. Provide a training facility that will conduct two-week virtual rotations in pharmacogenomic testing and interpretation and in cancer cytogenetics for our Ph.D. Medical Genetics trainees seeking certification in Laboratory Genetics and Genomics, To provide a genetic counselor to assist in the training of the fellows in the genetic counseling implications of the diagnoses that have been made.

To participate in the comprehensive training of all trainees in genetics as part of the Medical Genetics and Genomic Medicine Residency and Fellowship Training Programs.

Project title:

Training in Pediatrics through the combined Pediatrics/Genetics residency co-sponsored by CNH and NHGRI.

All details other details are provided in the Attached Statement of Work dated July 20, 2026.

PERIOD OF PERFORMANCE

September 30, 2026 – September 29, 2027

PLACE OF PERFORMANCE

Work shall be performed at Contractor’s location.

All Federal Acquisition Regulation (FAR) clauses may be viewed at https://www.acquisition.gov/browse/index/far.

EVALUATION OF QUOTATIONS:

The technical approach is the most important item in the evaluation of the contractor’s capability to perform the desired services. Therefore, the approach must present sufficient information to reflect a thorough understanding of the work requirements and a detailed technical approach for achieving project objectives as set forth in the services outlined in the attached SOW.

The award will be made on a non-competitive basis. The offeror’s quote will be evaluated to determine acceptability. The government reserves such right of flexibility in conducting the evaluation as necessary to assure an award to the contractor providing the best value to the government.

EVALUATION

The Contractor shall demonstrate its ability to provide the services as outlined in the attached statement of work.

SPECIAL NOTICE TO OFFERORS

Offerors are advised that the Government may share your information with non-government personnel who are assisting with the evaluation of quotes. The exclusive responsibility for source selection will reside with the Government. By submitting your quote, you will be consenting to disclosure of your quote to non-government personnel for purposes of evaluation.

PROVISIONS AND CLAUSES

By submitting a quote in response to this solicitation, vendor accepts the following terms and conditions:

The following FAR provisions apply to this acquisition:

FAR 52.212-1 Instructions to Offerors Commercial Items (SEP 2023) FAR 52.212-3 Offerors Representations and Certifications - Commercial Items (FEB 2024) FAR 52.204-7 System for Award Management (OCT 2018) (Offerors must complete annual representations and certifications on-line at http://www.sam.gov/ in accordance with FAR 52.212-3 Offerors Representations and Certifications- Commercial Items (Please ensure FAR 52.209-2 -- Prohibition on Contracting with Inverted Domestic Corporations--Representation. (Nov 2015) is updated in your SAM record) FAR 52.203-18 Prohibition on Contracting with Entities that Require Certain Internal Confidentiality Agreements – Representation (JAN 2017) 52.204–26 Covered Telecommunications Equipment or Services-Representation (OCT 2020) *** Must complete representation if attached to this solicitation- see attachment 52.204-26 By submitting a quote in response to this solicitation, vendor accepts the following terms and conditions:

The following FAR contract clauses apply to this acquisition:

FAR 52-212-4 Contract Terms and Conditions Commercial Items (NOV 2023) FAR 52.232-40 Providing Accelerated Payments to Small Business Subcontractors (MAR 2023) FAR 52.204-13 System for Award Management Maintenance (NOV 2025) FAR 52.204-25 Prohibition on Contracting for Certain Telecommunications and Video Surveillance Services or Equipment (NOV 2021) HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity Investigations (December 2015) FAR 52.252-2 -- Clauses Incorporated by Reference. (Feb 1998)

Instructions:

Offerors shall submit their quote electronically no later than 5:00 p.m. Eastern Daylight Savings Time (EDT) on September 28, 2026. Please see below for the content of the quote. Quotes shall be emailed to Linda Smith (Linda.Smith2@nih.gov) or (Jessica.Emerson@nih.gov). Offers shall include RFQ number in the subject line (RFQ-PCA-NHGRI-0361). Late submissions shall be treated in accordance with the solicitation provision at FAR 52.212-1(f). All responsible sources may submit an offer that will be considered by this Agency. Any questions or concerns regarding this solicitation should be forwarded in writing via e-mail to Jessica Emerson @ jessica.emerson@nih.gov or Linda Smith at Linda.smith2@nih.gov

This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at this address: http://farsite.hill.af.mil/vffara.htm. By submission of an offer, the offeror acknowledges the requirement that a prospective awardee shall be registered in the System for Award Management (SAM) database prior to award, during performance, and through final payment of any contract, basic agreement, basic ordering agreement, or blanket purchasing agreement resulting from this solicitation (www.sam.gov). Copies of the above-referenced provisions and clauses are available from http://www.acquisition.gov/far/loadmainre.html & http: //www.hhs.gov/regulation/index.html.

LIST OF ATTACHMENTS

Attachment 1 – SOW