RFA-HL-26-006-Full-Announcement.html

This document is a Request for Application (RFA) for the Viral INfections in the Young Lung (VINYL) Clinical Consortium, a research initiative by the National Heart, Lung and Blood Institute (NHLBI). The program aims to create a clinical consortium to perform deep phenotyping of 1,500 children aged 0-2 years hospitalized with viral lower respiratory tract infections (LRTI), with longitudinal follow-up until age 4-5 to assess pulmonary outcomes, particularly asthma. The study will focus on bronchiolitis, pneumonia, and pediatric acute respiratory distress syndrome, addressing critical knowledge gaps in understanding viral infections in young lungs.

The grant opportunity is part of the Lung Diseases Research Federal Grant Program (CFDA 93.838) under the Department of Health and Human Services National Institutes of Health. It will utilize UG3/UH3 activity codes to fund one Clinical Coordinating Center (CCC) and Biorepository along with four Clinical Centers (CCs). The research will involve comprehensive data collection, including neurocognitive development and sleep assessments, with the ultimate goal of identifying prognostic biomarkers and improving diagnosis and management of viral respiratory infections in young children. While applications are not currently being solicited, potential applicants are encouraged to develop collaborations and prepare for future submission.