RFA-ES-25-003-Full-Announcement.html

This is a Notice of Funding Opportunity (NOFO) from the Department of Health and Human Services National Institutes of Health (NIH) for time-sensitive environmental health research (RFA-ES-25-003). The funding supports research on unpredictable events, policy changes, natural and human-made disasters, and emerging environmental public health threats that require rapid sample collection or data gathering. The grant mechanism is R21 (Clinical Trials Not Allowed).

The NOFO features an expedited review process, with the entire cycle from submission to award taking 4-6 months, significantly shorter than typical NIH grant cycles. It falls under two CFDA programs: Environmental Health (93.113) and NIEHS Superfund Hazardous Substances Basic Research and Education (93.143). Eligible applicants include higher education institutions, government entities, tribal organizations, nonprofits, and small businesses. The distinguishing feature of this opportunity is the requirement for rapid review and funding to address time-sensitive research questions that must be implemented quickly.