RFA-DA-27-004-Full-Announcement.html

This document is a Request for Application (RFA) for the BRAIN Initiative's Theories, Models and Methods (TMM) research program, focused on developing computational tools for understanding dynamic brain circuits. The National Institute on Drug Abuse (NIDA), in collaboration with multiple NIH institutes and centers, intends to publish a Notice of Funding Opportunity (NOFO) to support research on computational methods for analyzing complex brain data. The program will provide funding for tool building and dissemination in neural circuit mechanisms, models of circuit structure and function, and computational analysis methods spanning neuron-level and behavioral scales.

The research initiative aims to characterize fundamental principles of brain function, neural computations, and brain-wide neural dynamics, with potential applications in developing treatments for neurological disorders like Parkinson's disease and major depressive disorder. While applications are not currently being solicited, potential applicants are encouraged to develop collaborations and responsive projects. The grant will utilize the R01 activity code, targeting investigators with expertise in computational models, neural computations, and artificial intelligence. The program emphasizes interdisciplinary research that combines mechanistic, interpretable, and predictive models of neural dynamics across different research domains.