PKG00286300.pdf

This is an application guide document for NIH FORMS-H grants that references both general and research-specific instructions for applicants. The document directs users to consult the General Instructions (HTML/PDF) or filtered Research Instructions (PDF) when applying, with links to the NIH grants portal providing access to these materials. Application form packages may contain optional forms, and applicants must review both the funding opportunity announcement and application instructions to determine submission requirements. The guide emphasizes using the research instructions when applying to research-focused opportunities and notes that form packages vary by program.

The document is paired with the Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required) grant opportunity, sponsored by the Department of Health and Human Services National Institutes of Health. This program supports small-scale research projects at institutions receiving no more than $6 million annually in NIH funding for 4 of the last 7 fiscal years and must award baccalaureate science degrees. The program specifically supports investigator-initiated mechanistic and/or minimal-risk clinical trials addressing participating NIH institute missions. The application deadline is January 7, 2027. Recent awards have ranged from approximately $100,000 to over $14 million, with typical project durations of 2–5 years. Eligible applicants include HBCUs, TCCUs, Asian American and Native American Pacific Islander Serving Institutions, Hispanic-serving institutions, and Alaska Native and Native Hawaiian Serving Institutions; non-domestic entities and foreign components of U.S. organizations are ineligible. The program operates under nine associated federal grant programs spanning cancer research, cardiovascular diseases, lung diseases, mental health, substance abuse, child health, nursing research, vision research, neuroscience, and aging research, collectively obligating billions in federal funding across tens of thousands of awards.