PKG00283231.pdf

This file is an Application Guide for NIH FORMS-H submissions related to the Specialized Programs of Research Excellence (SPOREs) in Human Cancers grant opportunity. Applicants must use either the General Instructions or the filtered Multi-project Instructions, with the latter required for multi-project applications. Optional forms may be included in the application package, and applicants should consult both the funding opportunity announcement and application instructions for specific submission requirements. The guide directs users to multiple NIH resources including the general application guide, forms-specific instructions, and separate guidance documents for multi-project applications.

The associated funding opportunity is a P50 Research Center Grant through the National Cancer Institute for SPORE programs spanning fiscal years 2024-2026, with a clinical trial requirement. The program supports translational research on organ-specific cancers or highly related cancer groups with the goal of reaching human clinical endpoints. Eligible applicants include academic institutions, HBCUs, minority-serving institutions, tribal colleges, faith-based organizations, federal agencies, and regional organizations, though non-domestic entities and foreign components are not eligible. The opportunity falls under CFDA 93.395 (Cancer Treatment Research) and 93.121 (Oral Diseases and Disorders Research), administered by the National Institutes of Health under the Department of Health and Human Services. Applications are evaluated on scientific merit, technical adequacy, investigator competency, facility adequacy, budget necessity, and program relevance, with review conducted by scientific peer review groups and the National Cancer Advisory Board.