PAR-27-067-Full-Announcement.html

Department of Health and Human Services

Part 1. Overview Information

Participating Organization(s)

National Institutes of Health (NIH)

Components of Participating Organizations

National Institute of General Medical Sciences (NIGMS)

National Eye Institute (NEI)

National Human Genome Research Institute (NHGRI)

National Institute on Aging (NIA)

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

National Institute of Biomedical Imaging and Bioengineering (NIBIB)

National Institute on Deafness and Other Communication Disorders (NIDCD)

National Institute of Dental and Craniofacial Research (NIDCR)

National Institute of Mental Health (NIMH)

National Institute of Neurological Disorders and Stroke (NINDS)

Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs (ORIP)

Funding Opportunity Title

Limited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)

Activity Code

S10 Biomedical Research Support Shared Instrumentation Grants

Announcement Type

Reissue of

PAR-23-138

Related Notices

Check for any recent Notices of NIH Policy Changes that may impact application requirements.

Funding Opportunity Number (FON)

PAR-27-067

Companion Funding Opportunity

None

Number of Applications

See Section III. 3. Additional Information on Eligibility.

Assistance Listing Number(s)

93.859, 93.286, 93.351, 93.172, 93.853, 93.121, 93.867, 93.866, 93.242, 93.846, 93.173

Funding Opportunity Purpose

The Instrumentation Grant Program for Resource-Limited Institutions supports the purchase of state-of-the-art scientific instruments to enhance the research and educational missions of resource-limited institutions. Requested instruments may support biomedical research and education in basic, translational, biomedically-related behavioral or clinical fields. This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered.

Funding Opportunity Goal(s)

The National Institute of General Medical Sciences (NIGMS) supports basic research that increases our understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment, and prevention. NIGMS also supports research in specific clinical areas that affect multiple organ systems: anesthesiology and peri-operative pain; clinical pharmacology common to multiple drugs and treatments; and injury, critical illness, sepsis, and wound healing. NIGMS-funded scientists investigate how living systems work at a range of levels–from molecules and cells to tissues and organs–in research organisms, humans, and populations. Additionally, to ensure the vitality and continued productivity of the research enterprise, NIGMS provides leadership in supporting the training of future scientists and developing research capacity throughout the country.

Key Dates

Posted Date

May 27, 2026

Open Date (Earliest Submission Date)

June 02, 2026

July 02, 2026

Not Applicable

Not Applicable

April 2027

January 26, 2027

Not Applicable

Not Applicable

December 2027

July 02, 2027

Not Applicable

Not Applicable

April 2028

January 26, 2028

Not Applicable

Not Applicable

December 2028

July 03, 2028

Not Applicable

Not Applicable

April 2029

January 26, 2029

Not Applicable

Not Applicable

December 2029

All applications are due by 5:00 PM local time of applicant organization.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Expiration Date

January 27, 2029

Due Dates for E.O. 12372

Not Applicable

Required Application Instructions

It is critical that applicants follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide, except where instructed to do otherwise (in this NOFO or in a Notice from NIH Guide for Grants and Contracts).

Conformance to all requirements (both in the How to Apply - Application Guide and the NOFO) is required and strictly enforced. Applicants must read and follow all application instructions in the How to Apply - Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the How to Apply - Application Guide, follow the program-specific instructions.

Applications that do not comply with these instructions may be delayed or not accepted for review.

Table of Contents

Part 1. Overview Information Key Dates Part 2. Full Text of Announcement Section I. Notice of Funding Opportunity Description Section II. Award Information Section III. Eligibility Information Section IV. Application and Submission Information Section V. Application Review Information Section VI. Award Administration Information Section VII. Agency Contacts Section VIII. Other Information

Part 2. Full Text of Announcement

Section I. Notice of Funding Opportunity Description

Need for the Program Developing a highly skilled biomedical research workforce is essential to strengthening the nation's economic competitiveness and improving public health. Hands-on, active learning using modern equipment has been shown to significantly boost student interest and educational achievement in scientific fields, thereby expanding the talent pool for the U.S. biomedical research enterprise. The Instrumentation Grant Program for Resource-Limited Institutions (RLI-S10) aims to increase biomedical research capacity and educational opportunities at resource-limited institutions by supporting their purchase of modern scientific instruments. This is a NOFO for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Program Objectives This Notice of Funding Opportunity (NOFO) invites applications from institutions that have limited NIH Research Project Grant (RPG) funding, to purchase scientific equipment (see Section III.1 for details on institutional eligibility). Proposed instruments may support scientific projects in NIH-supported basic, translational, clinical, or biomedically-related behavioral fields. Students and trainees may also benefit from access to the instrument in formal courses. The requested instrument should invigorate current research, foster new research projects, stimulate collaborations, and enhance education.

Expectations The requested instrument should be housed at the recipient institution and placed in a space that maximizes sharing, promotes cost-effectiveness, and fosters a collaborative multi-disciplinary environment. Examples of suitable spaces include a core facility, a shared-resource space, or an accessible laboratory, which may serve as a teaching space.

The applicant institution should propose a Program Director/Principal Investigator (PD/PI) who will assume administrative and scientific oversight of the requested instrument. Multiple PDs/PIs are not allowed.

The PD/PI is responsible for the instrument's organizational plan (Section IV.2) and:

Each application should have at least three Major Users with research projects or educational activities that demonstrate a significant need for the requested instrument (see Section III.3 Additional Information on Eligibility).

Technical expertise is required to manage the instrument, but it does not need to be handled by a dedicated staff member. This funding opportunity does not allow budgeting salaries for technical personnel.

Allowable equipment This NOFO provides funds to purchase a single, specialized, commercially available instrument or an integrated instrumentation system. An integrated instrumentation system consists of components that, when used together, perform a function that no single component can achieve. The components must be dedicated to the system and not used independently. Supported instrument types include, but are not limited to: basic cell sorters, confocal microscopes, ultramicrotomes, gel imagers, mass spectrometers, benchtop NMR spectrometers, optical instruments such as fluorimeters or CD spectropolarimeters, centrifuges, 3D printers, micro-plate-readers equipped with optical systems for high-throughput measurements, FPLCs and HPLCs, and computer systems.

Applications for stand-alone computer systems (e.g., computer clusters and data storage systems) will only be considered if the system is solely dedicated to biomedical research and/or education and alternative access to such services (e.g., commercial cloud services) is not feasible or cost-effective.

Exclusions Applications with the following characteristics will be considered non-responsive to this NOFO and administratively withdrawn:

Applicants are strongly encouraged to discuss any questions about appropriate types of equipment, eligibility, and program requirements with the appropriate Scientific/Research Contact (See Section VII) prior to submitting an application.

See Section VIII. Other Information for award authorities and regulations.

Section II. Award Information

Funding Instrument

Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.

Application Types Allowed

New

The OER Glossary and the How to Apply - Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.

Clinical Trial?

Not Allowed: Only accepting applications that do not propose clinical trials. Note: Applications may propose activities involving human subjects that are not deemed clinical trials.

Need help determining whether you are doing a clinical trial?

Funds Available and Anticipated Number of Awards

The number of awards is contingent upon NIH appropriations and the submission of meritorious applications.

Award Budget

Since different instruments will range in cost, the amount of the award will vary. The minimum award is $25,000 and, although there is no upper limit on the cost of the instrument, the maximum award is $250,000. No indirect costs are allowed for S10 awards.

Applicants should employ the most economical approaches, including securing academic discounts, to formulate a cost-effective budget while meeting users' scientific and educational needs. See Section IV.6 Funding Restrictions for additional details.

Service contract costs for up to 5 years may be included in the budget but must be paid during the period of the award.

Award Project Period

Awards are made for one year only.

NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.

Section III. Eligibility Information

1. Eligible Applicants

Eligible Organizations

Nonprofits Other Than Institutions of Higher Education

For-Profit Organizations

Local Governments

Federal Governments

Eligible Agencies of the Federal Government

U.S. Territory or Possession

Other

Independent School Districts

Public Housing Authorities/Indian Housing Authorities

Native American Tribal Organizations (other than Federally recognized tribal governments)

Faith-based or Community-based Organizations

Regional Organizations

or belong to one of the following categories:

For institutions with multiple campuses, eligibility can be considered for an individual campus (e.g., main, satellite, etc.) as the applicant organization only if a Unique Entity Identifier (UEI) and a unique NIH eRA Institutional Profile Fle (IPF) number are established for the individual campus. For institutions that use one UEI or NIH IPF number for multiple campuses, eligibility as the applicant organization is determined for the campuses together.

Foreign Organizations/Foreign Collaborations

Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Required Registrations

Applicant Organizations Applicant organizations must complete and maintain the following registrations as described in the How to Apply - Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. Failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications for additional information System for Award Management (SAM) – Applicants must complete and maintain an active registration, which requires renewal at least annually. The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. Foreign organizations must obtain a NATO Commercial and Government Entity (NCAGE) Code (in lieu of a CAGE code) in order to register in SAM. Unique Entity Identifier (UEI)- A UEI is issued as part of the SAM.gov registration process. The same UEI must be used for all registrations, as well as on the grant application.

Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

All PD(s)/PI(s) must be registered with ORCID. The personal profile associated with the PD(s)/PI(s) eRA Commons account must be linked to a valid ORCID ID. For more information on linking an ORCID ID to an eRA Commons personal profile see the ORCID topic in our eRA Commons online help.

Eligible Individuals (Program Director/Principal Investigator)

Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with their organization to develop an application for support.

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the How to Apply - Application Guide.

Only PDs/PIs associated with the eligible applicant organizations as outlined above may apply. Multiple PDs/PIs are not allowed.

2. Cost Sharing This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement NIH Grants Policy Statement Section 1.2 Definition of Terms.

3. Additional Information on Eligibility Number of Applications

Applicant organizations may submit more than one application, provided that each application is scientifically distinct.

The NIH will not accept duplicate or highly overlapping applications under review at the same time, per NIH Grants Policy Statement Section 2.3.7.4 Submission of Resubmission Application. This means that the NIH will not accept:

Applicant organizations may submit more than one application, provided that each application is for a different type of instrument. However, multiple awards to a single institution in one fiscal year is unlikely. Applicant organizations are advised to consult with a Scientific/Research Contact (Section VII) to discuss potential instrument overlap before submitting multiple applications.

Major User Requirements At least three Major Users for the instrument are required at the time of application submission. Once this requirement has been met, other users may be added. There is no requirement that the PD/PI nor any Major User have an existing NIH award in order to apply to this NOFO.

Major Users can include:

In addition,

Applications will be withdrawn for failure to meet the eligibility requirements for Major Users at the time of submission.

Section IV. Application and Submission Information

1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants.gov Workspace or an institutional system-to-system solution. Links to apply using ASSIST or Grants.gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission It is critical that applicants follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide except where instructed in this notice of funding opportunity to do otherwise (in this NOFO, in a policy notice, or other notice from NIH Guide for Grants and Contracts). Conformance to the requirements in the How to Apply - Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.

Page Limitations All page limitations described in the How to Apply – Application Guide and the Table of Page Limits must be followed.

Lack of adherence to these Page Limitations will result in withdrawal of an application without review.

Instructions for Application Submission

The following section supplements the instructions found in the How to Apply – Application Guide and should be used for preparing an application to this NOFO.

SF424(R&R) Cover All instructions in the How to Apply - Application Guide must be followed.

Descriptive Title: Enter the generic name of the instrument requested in the title (for example, "Confocal Microscope" or "Plate Reader Equipped with Fluorescence Optics").

Estimated Project Funding:

Total Federal Funds Requested: Enter the total Federal funds for the requested instrument. This amount cannot exceed $250,000, the maximum award under this program. If the cost of the instrument is more than $250,000, enter $250,000 (or any lower amount of requested Federal Funds).

Total Non-Federal Funds: If Total Federal Funds Requested (described immediately above) and Total Federal & Non-Federal Funds (described immediately below) differ, enter the difference in this line. Explain how the difference will be paid in the Equipment section on the SF424 (R&R) Other Project Information form (described below).

Total Federal & Non-Federal Funds: Enter the total cost of the instrument from the quote.

Estimated Program Income: Enter zero as this does not apply to this NOFO.

SF424(R&R) Project/Performance Site Locations

SF424(R&R) Other Project Information

Project Summary/Abstract: Provide a succinct and accurate description of the requested instrument and explain the need for the instrument. Concisely state the application's broad, long-term objectives. Describe how access to the instrument will stimulate biomedical research and/or support education at the institution(s). This section should be informative to individuals working in the same or related fields and understandable to a scientifically or technically literate reader.

Note: The Project Summary/Abstract must be no longer than 30 lines of text.

Project Narrative: Using no more than two or three sentences, describe the relevance of the instrument to public health and its impact on research and education at the applicant institution. Be concise and use language that is clear and understandable to a general audience.

Bibliography & References Cited: List only publications that demonstrate the researchers' expertise in operation and usage of the requested instrument or are relevant to projects that will be supported by the instrument. References from the Research/Education Projects Section may be included in this section or listed at the end of individual subsections.

Facilities & Other Resources: Not Applicable. Do not include an attachment here.

Equipment:

Instrument service contracts are encouraged and should be included within the quote and requested in the budget. Up to five years of service contract may be purchased with this award.

Applications without a quote will be deemed incomplete and withdrawn without review.

If the requested funds do not cover the total instrument cost, the application should include a description of the proposed source(s) of funding to cover the remaining costs of the instrument and document their availability with a letter signed by an appropriate institutional official (see Letters of Support instruction below).

Other Attachments: The application must include the following two attachments: 1.Instrumentation Plan and 2. Letter(s) of Support. Refer to the Page Limitations section above for information about the page limits for the three sections of the Instrumentation Plan.

Instrumentation Plan

The Instrumentation Plan (with the sections described below) must be included as a single PDF file titled "Instrumentation Plan" and uploaded as a distinct attachment. Organize the Instrumentation Plan as specified below, starting each section with the appropriate section heading: Plan for Research and Education Capacity Building, Technical Expertise, and Organizational Plan. Do not include animations, videos, or links to websites.

2. Letters of Support All letters of support should be combined in a single PDF named "Letters of Support" and uploaded as a distinct attachment. This combined file must include a letter(s) from the Authorized Organization Representative (AOR) or Business Official or similar official with institution-wide responsibility that certifies:

If applicable, a letter(s) of support, from appropriate institutional officials, should also address the following:

SF424(R&R) Senior/Key Person Profile

The PD/PI, Major Users (and technical staff, as applicable) must include a Biographical Sketch Common Form and NIH Biographical Supplement.

The Personal Statement in the NIH Biographical Supplement should be tailored to the unique attributes and requirements of this program; the PD/PI, Major Users, Laboratory Course Instructors and, if appropriate, technical staff should describe the following in the Personal Statement of the NIH Biographical Supplement:

R&R Budget

Do not provide budget forms.

R&R Subaward Budget

Do not provide subaward budget forms.

PHS 398 Cover Page Supplement

Other Plan(s):

A Data Management and Sharing Plan (DMS Plan) is not applicable to this NOFO.

PHS Assignment Request Form

3. Unique Entity Identifier and System for Award Management (SAM) See Part 2. Section III.1 for information regarding the requirement for obtaining a unique entity identifier and for completing and maintaining active registrations in System for Award Management (SAM), NATO Commercial and Government Entity (NCAGE) Code (if applicable), eRA Commons, and Grants.gov

4. Submission Dates and Times Part I. contains information about Key Dates and times. Applicants are encouraged to submit applications before the due date to ensure they have time to make any application corrections that might be necessary for successful submission. When a submission date falls on a weekend or Federal holiday, the application deadline is automatically extended to the next business day.

Organizations must submit applications to Grants.gov (the online portal to find and apply for grants across all Federal agencies). Applicants must then complete the submission process by tracking the status of the application in the eRA Commons, NIH's electronic system for grants administration. NIH and Grants.gov systems check the application against many of the application instructions upon submission. Errors must be corrected and a changed/corrected application must be submitted to Grants.gov on or before the application due date and time. If a Changed/Corrected application is submitted after the deadline, the application will be considered late. Applications that miss the due date and time are subjected to the NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications.

Applicants are responsible for viewing their application before the due date in the eRA Commons to ensure accurate and successful submission.

Information on the submission process and a definition of on-time submission are provided in the How to Apply – Application Guide.

5. Intergovernmental Review (E.O. 12372) This initiative is not subject to intergovernmental review.

6. Funding Restrictions All NIH awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement.

Pre-award costs are allowable only as described in the NIH Grants Policy Statement Section 7.9.1 Selected Items of Cost.

Applications will be awarded for a period of one year and are not renewable.

Under the S10 program, funding requests are limited to the purchase cost including shipping, any applicable taxes and import duties/tariffs, as well as extended warranties and service contracts for the instrument only. Support for technical personnel, software (except as defined in Section I. Funding Opportunity Description), and supplies are not allowable. Cost sharing for the purchase of the instrument is not required and any institutional funds contributed to the costs of the purchase of the instrument are voluntary. If the requested funds do not cover the total instrument cost, the application should describe the proposed source(s) of funding to cover the balance of the cost of the instrument and document institutional support in a letter signed by an appropriate institutional official. Note that any voluntarily committed cost will appear in the Notice of the Award and the institution must comply with the commitment and reporting requirements.

This Program does not provide facilities and administrative (F&A) costs or support for construction, alterations or renovations. Matching funds are not required. However, commitment of an appropriate level of institutional support, to ensure the associated sustaining infrastructure, is expected and should be described in Letters of Support.

7. Other Submission Requirements and Information Applications must be submitted electronically following the instructions described in the How to Apply - Application Guide. Paper applications will not be accepted.

Applicants must complete all required registrations before the application due date. Section III. Eligibility Information contains information about registration.

For assistance with your electronic application or for more information on the electronic submission process, visit How to Apply – Application Guide. If you encounter a system issue beyond your control that threatens your ability to complete the submission process on-time, you must follow the Dealing with System Issues guidance. For assistance with application submission, contact the Application Submission Contacts in Section VII.

Important reminders:

All PD(s)/PI(s) must include their eRA Commons ID in the Credential field of the Senior/Key Person Profile form. Failure to register in the Commons and to include a valid PD/PI Commons ID in the credential field will prevent the successful submission of an electronic application to NIH. See Section III of this NOFO for information on registration requirements.

The applicant organization must ensure that the unique entity identifier provided on the application is the same identifier used in the organization's profile in the eRA Commons and for the System for Award Management. Additional information may be found in the How to Apply - Application Guide.

See more tips for avoiding common errors.

Upon receipt, applications will be evaluated for completeness and compliance with application instructions by the Center for Scientific Review and responsiveness by components of participating organizations, NIH. Applications that are incomplete, non-compliant and/or nonresponsive will not be reviewed.

Mandatory Disclosure

Recipients or subrecipients must submit any information related to violations of federal criminal law involving fraud, bribery, or gratuity violations potentially affecting the federal award. See Mandatory Disclosures, 2 CFR 200.113 and NIH Grants Policy Statement Section 4.1.35.

Send written disclosures to the NIH Chief Grants Management Officer listed on the Notice of Award for the IC that funded the award and to the HHS Office of Inspector Grant Self Disclosure Program at grantdisclosures@oig.hhs.gov.

Post Submission Materials Applicants are required to follow the instructions for post-submission materials, as described in the policy

No animations/videos are allowed.

Section V. Application Review Information

1. Criteria Only the review criteria described below will be considered in the review process. Applications submitted to the NIH in support of the NIH mission are evaluated for scientific and technical merit through the NIH peer review system.

This program is intended to strengthen both the biomedical research and educational capacity of resource-limited institutions and the instrument can be dedicated to a combination of research and/or laboratory coursework. There is no requirement or expectation that eligible institutions have existing NIH or other federally funded research programs. Although technical expertise to manage and use the instrument is expected, the application is not required to name dedicated technical staff to operate and manage the instrument. A faculty member who is a Major User or the PD/PI may serve in this capacity. The Parent S10 requires extensive plans for shared use and time allocation, which would be overly burdensome for a limited-resource institution; therefore, the RLI S10 requires a brief, higher-level organizational plan.

Overall Impact

Reviewers will provide an overall impact score to reflect their assessment of the likelihood for the project to exert a sustained, powerful influence on the research field(s) involved, in consideration of the following review criteria and additional review criteria (as applicable for the project proposed).

Scored Review Criteria

Reviewers will consider each of the review criteria below in the determination of scientific merit and give a separate score for each. An application does not need to be strong in all categories to be judged likely to have major scientific impact. For example, a project that by its nature is not innovative may be essential to advance a field.

Justification of Need

Is the need for the instrument clearly and adequately justified? Are all specific features, special accessories, (and, if applicable, the software configuration) of the requested instrument suitable for the described research and educational uses? Does the justification of the selected requested information include a comparison with other commercially available instruments of similar function?

Technical Expertise

Is sufficient technical expertise available to effectively use the requested instrument, including setup, operation, and user training (including any manufacturer-provided training)? Are the assigned personnel qualified to safely operate and maintain the instrument, and assess the instrument's performance?

Research and Education Projects

Will research with the requested instrument advance the knowledge and understanding of the proposed projects and/or are the proposed educational uses of the instrument appropriate and engaging for students?

Administration

Is the plan for the management and maintenance of the requested instrument appropriate? If needed, are the policies to manage projects which have human subjects, animals, or biohazards adequate? Is the post-award plan for instrument operation and maintenance the expected lifetime of the instrument (beyond the warranty or service contract) reasonable?

Institutional Commitment

Does the institutional commitment letter demonstrate a strong commitment to housing, maintaining, and providing user access to the instrument? If applicable, has the institution (based on the data in the table of Previously Awarded S10 Instruments in the institutional Letter of Support) accomplished the program's goals of enhancing research and educational capacity?

Additional Review Criteria

As applicable for the requested instrument, reviewers will evaluate the following additional items while determining capacity building merit, and in providing an overall benefit score, but will not give separate scores for these items.

Protections for Human Subjects

Generally not applicable. Reviewers should bring any concerns to the attention of the Scientific Review Officer.

This NOFO only accepts applications that do not propose clinical trials. Note: Applications may propose activities involving human subjects that are not deemed clinical trials.

Inclusion of Human Subjects Policies

Generally not applicable. Reviewers should bring any concerns to the attention of the Scientific Review Officer.

Vertebrate Animals

Generally not applicable. Reviewers should bring any concerns to the attention of the Scientific Review Officer.

Biohazards

Reviewers will assess whether materials or procedures…