PAR-27-054-Revised-Full-Announcement.html

Department of Health and Human Services

Part 1. Overview Information

Participating Organization(s)

National Institutes of Health (NIH)

Components of Participating Organizations

National Institute of General Medical Sciences (NIGMS)

Note: Not all NIH Institutes, Centers, and Offices (ICOs) participate in Announcements. Applicants should carefully note which ICOs participate in this announcement and view their respective areas of research interest at the ICO-Specific Scientific Interests website. ICOs that do not participate in this announcement will not consider applications for funding.

Funding Opportunity Title

Limited Competition: Centers of Biomedical Research Excellence: Development Phase (COBRE-D) (P30 - Clinical Trial Not Allowed)

Activity Code

P30 Center Core Grants

Announcement Type

Reissue of

PAR-22-250

Related Notices

Funding Opportunity Number (FON)

PAR-27-054

Companion Notice of Funding Opportunity

None

Number of Applications

Only one application per institution is allowed, as defined in Section III. 3. Additional Information on Eligibility.

Assistance Listing Number(s)

93.859

Notice of Funding Opportunity Purpose

The Institutional Development Awards (IDeA) program supports biomedical research capacity building in states that have historically received low levels of NIH funding. The Centers of Biomedical Research Excellence: Development Phase (COBRE-D) program supports institutions in IDeA states to increase their biomedical research capacity in a broad scientific area of strategic importance to them but for which they have limited existing infrastructure or expertise.

COBRE-D supports a long-term institutional vision focused on the recruitment and mentoring of early-career investigators with supplemental start-up packages for new hires, the establishment of research facilities, and enhancement of research administration support services. This program serves as an on-ramp for less-resourced institutions to the Centers of Biomedical Research Excellence: Expansion/Sustainability Phases (COBRE-E/S) program. This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered.

Funding Opportunity Goal(s)

To ensure the vitality and continued productivity of the research enterprise, NIGMS provides leadership in supporting the training of future scientists and developing research capacity throughout the country.

Key Dates

Posted Date

August 19, 2026

Open Date (Earliest Submission Date)

August 25, 2026

The following table includes NIH standard due dates marked with an asterisk.

September 25, 2026 *

September 25, 2026 *

Not Applicable

July 2027

January 25, 2027 *

January 25, 2027 *

Not Applicable

December 2027

May 25, 2027 *

May 25, 2027 *

Not Applicable

April 2028

September 25, 2027 *

September 25, 2027 *

Not Applicable

July 2028

January 25, 2028 *

January 25, 2028 *

Not Applicable

December 2028

May 25, 2028 *

May 25, 2028 *

Not Applicable

April 2029

September 25, 2028 *

September 25, 2028 *

Not Applicable

July 2029

January 25, 2029 *

January 25, 2029 *

Not Applicable

December 2029

May 25, 2029 *

May 25, 2029 *

Not Applicable

April 2030

All applications are due by 5:00 PM local time of applicant organization.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Expiration Date

May 26, 2029

Due Dates for E.O. 12372

Not Applicable

Required Application Instructions

It is critical that applicants follow the Multi-Project (M) Instructions in the How to Apply - Application Guide, except where instructed to do otherwise (in this NOFO or in a Notice from the NIH Guide for Grants and Contracts). Conformance to all requirements (both in the How to Apply - Application Guide and the NOFO) is required and strictly enforced. Applicants must read and follow all application instructions in the How to Apply - Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the How to Apply - Application Guide, follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.

Table of Contents

Part 1. Overview Information Key Dates Part 2. Full Text of Announcement Section I. Notice of Funding Opportunity Description Section II. Award Information Section III. Eligibility Information Section IV. Application and Submission Information Section V. Application Review Information Section VI. Award Administration Information Section VII. Agency Contacts Section VIII. Other Information

Part 2. Full Text of Announcement

Section I. Notice of Funding Opportunity Description

This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered.

Authorized by the U.S. Congress in 1993, the National Institutes of Health (NIH) established the Institutional Development Award (IDeA) program to build biomedical research capacity in 23 U.S. states and Puerto Rico (See Section III for IDeA state eligibility), which had historically low NIH grant funding success rates. IDeA funding programs collectively support biomedical research in basic, clinical, behavioral, and translational science in IDeA-eligible states by developing faculty investigators, providing research opportunities to students, and enhancing research infrastructure.

One of the components of IDeA is the Centers of Biomedical Research Excellence (COBRE) program, which supports the establishment and development of innovative biomedical research centers of excellence in an area of strategic importance to the organization and in alignment with the mission and priorities of the NIH. The COBRE program has two tracks that provide grant recipients with the means to build biomedical research capacity:

This Notice of Funding Opportunity (NOFO) only supports applications to the COBRE-D phase of the program. The companion NOFO (PAR-27-055) supports applications to the COBRE-E and COBRE-S phases of the program.

The five-year phases of the COBRE program are:

COBRE-D Program Overview Applicant organizations must identify a key strategic biomedical scientific area where existing research infrastructure and early- and mid-career investigators are currently lacking. The proposed research area should be sufficiently broad to establish the scientific foundation for the growth and development of biomedical research capacity in alignment with the organization's strategic priorities. Applications proposing partnerships between two organizations lacking biomedical research capacity in the planned area of research are allowed.

The COBRE-D structure includes an initial ramp-up period (up to 12 months) during the first budget period to build the necessary organizational framework necessary to develop outreach, recruit faculty, and strengthen research infrastructure. This will involve recruitment of 3 to 6 early to mid-career investigators during the span of the award and integration of the following cores:

COBRE-D grant recipients are expected to accomplish the following measurable objectives:

See Section VIII. Other Information for award authorities and regulations.

Section II. Award Information

Funding Instrument

Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.

Application Types Allowed

New

Revision

The OER Glossary and the How to Apply - Application Guide provides details on these application types. Only those application types listed here are allowed for this NOFO.

Clinical Trial?

Not Allowed: Only accepting applications that do not propose clinical trials.

Need help determining whether you are doing a clinical trial?

Funds Available and Anticipated Number of Awards

The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Award Budget

Application budgets are limited to $400,000 direct costs during year 1 and $1.8 million in annual direct costs in years 2-5.

Award Project Period

The project period is limited to five years.

NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.

Section III. Eligibility Information

1. Eligible Applicants

Eligible Organizations

Nonprofits Other Than Institutions of Higher Education

Foreign Organizations/International Collaborations

Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Foreign PIs or organizations may use center resources as a fee-for-service. In such cases, resulting publications cannot cite or acknowledge NIH grant support.

Required Registrations

Applicant organizations Applicant organizations must complete and maintain the following registrations as described in the How to Apply- Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. Failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications for additional information.

System for Award Management (SAM) – Applicants must complete and maintain an active registration, which requires renewal at least annually. The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. Foreign organizations must obtain a NATO Commercial and Government Entity (NCAGE) Code (in lieu of a CAGE code) in order to register in SAM. Unique Entity Identifier (UEI)- A UEI is issued as part of the SAM.gov registration process. The same UEI must be used for all registrations, as well as on the grant application.

Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. Obtaining an eRA Commons account can take up to 2 weeks.

All PD(s)/PI(s) must be registered with ORCID. The personal profile associated with the PD(s)/PI(s) eRA Commons account must be linked to a valid ORCID ID. For more information on linking an ORCID ID to an eRA Commons personal profile see the ORCID topic in our eRA Commons online help.

Eligible Individuals (Program Director/Principal Investigator)

Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support.

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the How to Apply - Application Guide.

The PD/PI is expected to be an established biomedical research scientist with the mentoring and administrative experience necessary to lead the Center. At the time of submission, the PD/PI must have a primary appointment at the applicant organization and be the PD/PI on at least one active, peer-reviewed and externally funded research grant within the same general scientific area of the proposed COBRE. If a COBRE PD/PI's qualifying research grant is a multiple PD/PI award to a different organization, the applicant organization must receive funds via a subcontract. For multiple PD/PI COBRE applications, all non-contact PDs/PIs must have at least one active, peer-reviewed, and externally funded research grant within the same general scientific area of the center.

A COBRE PD/PI may not simultaneously lead more than one IDeA (INBRE, CTR, or other COBRE) program award. Previous PDs/PIs of other COBRE Centers, except those who served in that capacity on an interim basis, are not eligible to lead a COBRE-D application. All investigators who intend to apply as PDs/PIs are encouraged to consult with the Scientific/Research Contact listed in Section VII prior to preparing an application to confirm eligibility.

2. Cost Sharing This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement Section 1.2- Definitions of Terms.

3. Additional Information on Eligibility Number of Applications

Only one COBRE-D application per institution (normally identified by having a unique entity identifier (UEI) number or NIH IPF number) is allowed.

The NIH will not accept duplicate or highly overlapping applications under review at the same time per NIH Grants Policy Statement Section 2.3.7.4 Submission of Resubmission Application. This means that the NIH will not accept:

Section IV. Application and Submission Information

1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST or an institutional system-to-system solution. A button to apply using ASSIST is available in Part 1 of this NOFO. See the administrative office for instructions if planning to use an institutional system-to-system solution.

2. Content and Form of Application Submission It is critical that applicants follow the Multi-Project (M) Instructions in the How to Apply - Application Guide, except where instructed in this notice of funding opportunity to do otherwise (in this NOFO, in a policy notice, or other notice from NIH Guide for Grants and Contracts) and where instructions in the How to Apply - Application Guide are directly related to the Grants.gov downloadable forms currently used with most NIH opportunities. Conformance to the requirements in the How to Apply - Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.

Page Limitations All page limitations described in the How to Apply- Application Guide and the Table of Page Limits must be followed.

Required

Required

Optional

Required

Instructions for the Submission of Multi-Component Applications

The following section supplements the instructions found in How to Apply- Application Guide and should be used for preparing a multi-component application.

Overall Component When preparing the application, use Component Type 'Overall'.

All instructions in the How to Apply - Application Guide must be followed, with the following additional instructions, as noted.

SF424(R&R) Cover (Overall) Complete entire form.

PHS 398 Cover Page Supplement (Overall)

Research & Related Other Project Information (Overall) Follow standard instructions.

Project/Performance Site Locations (Overall) Enter primary site only.

A summary of Project/Performance Sites in the Overall section of the assembled application image in eRA Commons compiled from data collected in the other components will be generated upon submission.

Research and Related Senior/Key Person Profile (Overall) Include only the Project Director/Principal Investigator (PD/PI) and any multi-PDs/PIs (if applicable to this NOFO) for the entire application.

Biographical Sketch: Each PD/PI should include a description of their scientific, mentoring, and administrative experience in the Personal Statement of the NIH Biographical Sketch Supplement. The Biographical Sketch Common Form and NIH Biographical Sketch Supplement should provide evidence of the PD/PI's leadership experience in the center's broad area of research, mentoring of early and mid-career investigators, and administration. Each PD/PI should describe how their mentoring track record promotes independence, retention, and long-term success of early- and mid-career faculty.

Current & Pending Support: Attach a copy of the PD/PI's Current and Pending (Other) Support Common Form, which is critical information for determining the PD/PI's eligibility and suitability to lead the proposed center.

A summary of Senior/Key Persons followed by their Biographical Sketches in the Overall section of the assembled application image in eRA Commons will be generated upon submission.

Budget (Overall) The only budget information included in the Overall component is the Estimated Project Funding section of the SF424 (R&R) Cover.

A budget summary in the Overall section of the assembled application image in eRA Commons compiled from detailed budget data collected in the other components will be generated upon submission.

PHS 398 Research Plan (Overall) Introduction to Application: For Revision applications, an Introduction to Application is required in the Overall component.

Research Strategy: This section must include the following elements:

A. Justification for Establishment of the Center Applicants should provide a strong rationale for the need to request support for the Center in the chosen scientific area and how it fits within the applicant organization's strategic plan. The Center's research area should be sufficiently broad and cohesive to enable the development of long-term biomedical research capacity and to catalyze the recruitment and retention of early and mid-career investigators.

The justification should describe the organization's:

B. Organization and Management Plan The overall Organization and Management Plan for the Center should clearly convey a strategy that demonstrates an effective use of the available funding, the proposed configuration of the Center and its cores, and the approaches to develop biomedical research capacity. Describe:

C. Plan for an Internal Advisory Committee An Internal Advisory Committee (IAC) composed of one senior institutional official (for instance, Dean, Vice-President for Research), two senior faculty members appointed by the senior organizational official, and two other institutional stakeholders (for example., facility or sponsored programs managers) must be assembled to advise the PD(s)/PI(s).

Applicants should describe the IAC's planned composition, organization, and operation plans. The IAC is expected to meet frequently as the proposed plans are implemented. An IAC member may not hold any other position in the Center.

Responsibilities of the IAC include but are not limited to:

D. Faculty Development Plan A Faculty Development Plan is required and will be implemented by the Faculty Development Core to support the success of the early- and mid-career investigators hired into the center. Leadership and research management training should be integrated throughout center activities to foster career and professional advancement. Plans must address how new faculty will establish independent research programs and how, collectively, these investigators will enable scientific advances in a coherent, relevant, and broad area of biomedical research in alignment with organizational priorities.

Applicants should describe the characteristics that will be sought in prospective faculty hires with an eye towards strengthening the scientific coverage of the center. As part of the career development efforts, each early- and mid-career investigator supported by the center must be assigned a mentor. The mentor should be an established investigator who can provide both scientific guidance and career development advice. If a suitable mentor is not available at the applicant organization (or partner institution, if applicable), an appropriate mentor from another organization, including those in non-IDeA states, may be enlisted.

The Faculty Development Plan should describe:

Letters of Support: A single letter of support from a senior institutional official (for example., President or Dean) must be included outlining the institution's strategic plan and how the proposed COBRE-D aligns with institutional priorities for developing biomedical research capacity and addressing documented gaps in infrastructure or expertise. The letter must also provide detailed evidence of existing institutional resources and commitment to the Center's future vision for growth and long-term sustainability, including plans to build capacity toward future competitiveness for COBRE-E support.

If the application proposes a partnership between two institutions, each must provide a letter of support that outlines each partner's respective role in administering the center including how they will collaborate and share resources. The letters should describe how institutional support will be synergized to maximize the success of the center and must address plans for each institution to transition independently to COBRE-E.

Applications that do not include the required Letter(s) of Support will be considered incomplete, and the application will be withdrawn prior to review. Do not include any additional Letters of Support.

Resource Sharing Plan:

Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the How to Apply - Application Guide.

Other Plan(s):

All instructions in the How to Apply- Application Guide must be followed, with the following additional instructions:

A Data Management and Sharing Plan is not applicable for this NOFO.

Appendix:

Only limited items are allowed in the Appendix. Follow all instructions for the Appendix as described in How to Apply- Application Guide; any instructions provided here are in addition to the How to Apply - Application Guide instructions.

PHS Human Subjects and Clinical Trials Information (Overall) When involving human subjects research, clinical research, and/or NIH-defined clinical trials follow all instructions for the PHS Human Subjects and Clinical Trials Information form in the How to Apply - Application Guide, with the following additional instructions:

If you answered "Yes" to the question "Are Human Subjects Involved?" on the R&R Other Project Information form, there must be at least one human subjects study record using the Study Record: PHS Human Subjects and Clinical Trials Information form or a Delayed Onset Study record within the application. The study record(s) must be included in the component(s) where the work is being done, unless the same study spans multiple components. To avoid the creation of duplicate study records, a single study record with sufficient information for all involved components must be included in the Overall component when the same study spans multiple components.

Study Record: PHS Human Subjects and Clinical Trials Information All instructions in the How to Apply - Application Guide must be followed.

Delayed Onset Study

Note: Delayed onset does NOT apply to a study that can be described but will not start immediately (i.e., delayed start). All instructions in the How to Apply- Application Guide must be followed.

PHS Assignment Request Form (Overall) All instructions in the How to Apply- Application Guide must be followed.

Administrative Core When preparing your application, use Component Type 'Admin Core.' All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions, as noted.

SF424 (R&R) Cover (Administrative Core) Complete only the following fields:

PHS 398 Cover Page Supplement (Administrative Core) Follow standard instructions.

Research & Related Other Project Information (Administrative Core) Human Subjects: Answer only the 'Are Human Subjects Involved?' and 'Is the Project Exempt from Federal regulations?' questions.

Vertebrate Animals: Answer only the 'Are Vertebrate Animals Used?' question.

Project Narrative: Do not complete. Note: ASSIST screens will show an asterisk for this attachment indicating it is required. However, eRA systems only enforce this requirement in the Overall component and applications will not receive an error if omitted in other components.

Project /Performance Site Location(s) (Administrative Core) List all performance sites that apply to the specific component.

Note: The Project Performance Site form allows up to 300 sites, prior to using additional attachment for additional entries.

Research & Related Senior/Key Person Profile (Administrative Core)

Budget (Administrative Core) Budget forms appropriate for the specific component will be included in the application package.

The Administrative Core includes the faculty start-up and all administrative funds. The budget of the Administrative Core is limited to $1,300,000 in direct costs per year during years 2-5.

A minimum level of effort (LOE) of three person-months is required of each PD/PI to devote to administrative oversight of the center and provide career guidance to investigators. A maximum of two PDs/PIs are allowed in an MPI application. A PD/PI may not use COBRE funds to supplement research activities for their laboratory or research team and is not eligible for research support from this COBRE or any other COBRE, INBRE, or IDeA-CTR award.

Funds may be requested to:

Funds cannot be used by collaborators or for collaboration at organizations in non-IDeA states or at foreign sites. Funds may be used at other U.S. organizations for fee-for-service activities, such as learning new techniques, carrying out sample and data analysis, attending workshops, or obtaining scientific advising/consulting/mentoring (as described above).

The PD(s)/PI(s) of the center and faculty supported by the COBRE must attend the National IDeA Symposium of Biomedical Research Excellence (NISBRE) biennial meeting.

Note: The R&R Budget form included in many of the component types allows for up to 100 Senior/Key Persons in section A and 100 Equipment Items in section C prior to using attachments for additional entries. All other SF424 (R&R) instructions apply. (STANDARD TEXT) PHS 398 Research Plan (Administrative Core) Research Strategy: The Administrative Core implements the Center's plan, manages operations, and fulfills the COBRE award requirements. Include a description of:

Letters of Support: Not allowed.

PHS Human Subjects and Clinical Trials Information (Administrative Core) Not applicable to this component.

Research Core Research Core(s) should be made available to other investigators at the organization(s) as well as those from other IDeA state institutions. Core(s) that duplicate services already available at the applicant organization are not allowed. Utilization, modification, or expansion of existing resources supported by institutional funds, other IDeA programs, or federal funds to accomplish the goals of proposed COBRE research is strongly encouraged.

When preparing your application, use Component Type 'Core'. All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions, as noted.

SF424 (R&R) Cover (Research Core)

PHS 398 Cover Page Supplement (Research Core) Follow standard instructions.

Research & Related Other Project Information (Research Core) Human Subjects: Answer only the 'Are Human Subjects Involved?' and 'Is the Project Exempt from Federal regulations?' questions.

Vertebrate Animals: Answer only the 'Are Vertebrate Animals Used?' question.

Project Narrative: Do not complete. Note: ASSIST screens will show an asterisk for this attachment indicating it is required. However, eRA systems only enforce this requirement in the Overall component and applications will not receive an error if omitted in other components.

Project /Performance Site Location(s) (Research Core) Research Cores must be located at the primary performance site, or as applicable, at performance sites at a partner organization.

Note: The Project Performance Site form allows up to 300 sites, prior to using additional attachments for additional entries.

Research & Related Senior/Key Person Profile (Research Core)

The Director of a Research Core facility must be an experienced full-time staff member at the performance site with the requisite knowledge, authority, leadership, and administrative skills to direct the core. The Core Director will lead a team that:

Budget (Research Core) Budget forms appropriate for the specific component will be included in the application package. Funds may be requested to establish Research Core facilities and/or to use, modify, or expand existing resources needed to accomplish the scientific goals of the Center. In addition to personnel and supplies, acquisition of new equipment and modernization of instrumentation may be proposed. Alteration and Renovation (A&R) of core facilities is not allowed under this component. Core facilities should include a detailed budget for the entire proposed project period (five years).

Note: The R&R Budget form included in many of the component types allows for up to 100 Senior/Key Persons in section A and 100 Equipment Items in section C prior to using attachments for additional entries. All other SF424 (R&R) instructions apply.

PHS 398 Research Plan (Research Core) Research Strategy: Describe and justify:

Letters of Support: Not allowed.

PHS Human Subjects and Clinical Trials Information (Research Core) Not applicable to this component.

Faculty Development Core When preparing your application, use Component Type 'Faculty Core.' All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions, as noted.

SF424 (R&R) Cover (Faculty Development Core) Complete only the following fields:

PHS 398 Cover Page Supplement (Faculty Development Core) Follow standard instructions.

Research & Related Other Project Information (Faculty Development Core) Human Subjects: Answer only the 'Are Human Subjects Involved?' and 'Is the Project Exempt from Federal regulations?' questions.

Vertebrate Animals: Answer only the 'Are Vertebrate Animals Used?' question. Project Narrative: Do not complete. Note: ASSIST screens will show an asterisk for this attachment indicating it is required. However, eRA systems only enforce this requirement in the Overall component and applications will not receive an error if omitted in other components.

Project /Performance Site Location(s) (Faculty Development Core) List all performance sites that apply to the specific component.

Note: The Project Performance Site form allows up to 300 sites, prior to using additional attachment for additional entries.

Research & Related Senior/Key Person Profile (Faculty Development Core)

Budget (Faculty Development Core) Budget forms appropriate for the specific component will be included in the application package.

Funds should be requested to develop and support center-wide career, scientific, and professional development activities in alignment with the Faculty Development Plan. These may include seminar series, workshops, training programs, grant writing courses, and retreats, as well as access to consultants and training resources for COBRE-supported investigators. Faculty development costs may be higher in the early years of the program and lower in the later stages for managing the efforts, such as salaries for Faculty Development Core key personnel, travel for key personnel, and supplies to support faculty development.

PHS 398 Research Plan (Faculty Development Core) Research Strategy: The Faculty Development Core manages activities involving the development of faculty hires and center investigators and ensures their continued scientific and career advancement through implementation of the Faculty Development Plan. Applicant organizations should outline strategies for creating individual research development plans, career development approaches, and professional development activities for early- and mid-career faculty hires. The plans should aim to support career progression and foster a culture of excellence to retain faculty.

This section should include a description of:

Letters of Support: Not allowed.

PHS Human Subjects and Clinical Trials Information (Faculty Development Core) Not applicable to this component.

3. Unique Entity Identifier and System for Award Management (SAM) See Part 2. Section III.1 for information regarding the requirement for obtaining a unique entity identifier and for completing and maintaining active registrations in System for Award Management (SAM), NATO Commercial and Government Entity (NCAGE) Code (if applicable), eRA Commons, and Grants.gov

4. Submission Dates and Times Part I. contains information about Key Dates and times. Applicants are encouraged to submit applications before the due date to ensure they have time to make any application corrections that might be necessary for successful submission. When a submission date falls on a weekend or Federal holiday, the application deadline is automatically extended to the next business day.

Organizations must submit applications to Grants.gov (the online portal to find and apply for grants across all Federal agencies) using ASSIST or other electronic submission systems. Applicants must then complete the submission process by tracking the status of the application in the eRA Commons, NIH's electronic system for grants administration. NIH and Grants.gov systems check the application against many of the application instructions upon submission. Errors must be corrected and a changed/corrected application must be submitted to Grants.gov on or before the application due date and time. If a Changed/Corrected application is submitted after the deadline, the application will be considered late. Applications that miss the due date and time are subjected to the NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications.

Applicants are responsible for viewing their application before the due date in the eRA Commons to ensure accurate and successful submission.

Information on the submission process and a definition of on-time submission are provided in How to Apply- Application Guide.

5. Intergovernmental Review (E.O. 12372) This initiative is not subject to intergovernmental review.

6. Funding Restrictions All NIH awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement.

Pre-award costs are allowable only as described in the NIH Grants Policy Statement Section 7.9.1 Selected Items of Cost.

7. Other Submission Requirements and Information…