PAR-25-437-Full-Announcement.html

The file is a Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) for the Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Access program. The National Institutes of Health (NIH) plans to publish this opportunity in early summer 2025, with an expected application due date in July 2025, using the X01 activity code. The program aims to provide researchers access to ECHO Cohort data and biospecimen resources for studying high-priority areas of maternal and child health.

The ECHO Cohort dataset integrates longitudinal data from over 130,000 maternal and child participants, including prenatal and child environmental exposures across five primary pediatric outcome areas: pre-, peri-, and postnatal outcomes, upper and lower airway outcomes, obesity, neurodevelopment, and positive health. The Cohort Biorepository contains over 100,000 biospecimen samples. Proposed ancillary studies should investigate exposures from natural, built, physical, chemical, social, behavioral, and biological environments, and explore pathways linking these exposures to health outcomes. The grant opportunity falls under the Trans-NIH Research Support program (CFDA 93.310) and will be administered by the Department of Health and Human Services National Institutes of Health.