PAR-25-323-Full-Announcement.html

This document is a federal grant opportunity announcement for the Stephen I. Katz Early Stage Investigator Research Project Grant (R01) issued by the National Institutes of Health (NIH). The grant supports early stage investigators (ESIs) conducting basic experimental studies involving human participants, with a focus on research that represents a significant change in the investigator's research direction. Applicants must not include preliminary data and must submit a separate attachment describing the research direction change.

The grant opportunity is administered by the NIH and is specifically targeted at ESIs proposing innovative projects related to the programmatic interests of participating NIH Institutes and Centers. Eligible studies must prospectively assign human participants to conditions and assess biomedical or behavioral outcomes, with the primary goal of understanding fundamental aspects of phenomena without specific application towards processes or products. The grant is open to domestic public or private nonprofit or for-profit organizations, including universities, hospitals, and other research institutions. Proposals will undergo a comprehensive peer review process evaluating scientific merit, program relevance, and potential impact.