PAR-25-322-Full-Announcement.html

This document is a comprehensive federal grant opportunity announcement for the Stephen I. Katz Early Stage Investigator Research Project Grant (R01), issued by the National Institutes of Health (NIH). The grant is specifically designed for early stage investigators (ESIs) who wish to initiate research in an area distinctly different from their previous research focus or training experience, with the unique requirement that no preliminary data can be included in the application.

The grant opportunity supports an innovative project that represents a significant change in research direction, with applications requiring a separate attachment describing this directional shift. Eligible applicants must be early stage investigators proposing research related to the programmatic interests of participating NIH Institutes and Centers. If multiple Principal Investigators (MPIs) are proposed, all must be ESIs, and the research direction must represent a change for each. The grant is part of multiple federal grant programs under NIH, including Minority Health and Health Disparities Research, Cardiovascular Diseases Research, and Cancer Research, with potential funding through various NIH institutes such as the National Heart, Lung, and Blood Institute and the National Cancer Institute.