PAR-25-210-Full-Announcement.html

This document is a Notice of Funding Opportunity (NOFO) for the federal grant opportunity titled "Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)". The purpose of this NOFO is to support highly innovative mechanistic research to accelerate precision probiotic interventions. It seeks R33 applications that will characterize person-specific features affecting probiotic responses to identify subgroups of probiotic responders and enhance probiotic clinical outcomes. The goal is to identify, understand, and develop strategies to address barriers in precision probiotic therapies. The NOFO is intended to support projects where potential host biological patterns correlated with probiotic usage have been identified but require further mechanistic studies. Eligible applicant types include state governments, for-profit organizations, higher education institutions, small businesses, and various other entities. The funding agency is the Department of Health and Human Services National Institutes of Health, and the grant programs include NIH Office of Research on Women's Health, Cancer Cause and Prevention Research, Oral Diseases and Disorders Research, Research and Training in Complementary and Integrative Health, and Aging Research.