PAR-25-158-Full-Announcement.html

This Notice of Funding Opportunity (NOFO) PAR-25-158 is issued by the Department of Health and Human Services' National Institutes of Health for research on prevention and intervention strategies for fetal alcohol spectrum disorders (FASD). The funding uses an Exploratory/Developmental Phased Award (R61/R33) mechanism, with the R61 phase supporting pilot studies and hypothesis development, and the R33 phase allowing for expanded research pending achievement of R61 milestones as evaluated by NIAAA staff.

The opportunity is open to a wide range of applicants including state/local governments, higher education institutions, nonprofits, tribal organizations, and businesses. Funded under the Alcohol Research Programs (CFDA 93.273), it prioritizes clinical trials while also accepting secondary data analysis. The research must advance either prevention approaches to reduce prenatal alcohol exposure and FASD incidence, or interventions for FASD throughout the lifespan. Applicants interested in planning clinical trials may alternatively consider the R34 option under NOFO TEMP-23832.