PAR-25-122-Full-Announcement.html

This document is a Notice of Funding Opportunity (NOFO) for a federal grant program titled "Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)". The purpose of this NOFO is to solicit applications for pilot projects to elucidate a role for understudied proteins in rare diseases. Awards will support generation of preliminary data and/or tools around eligible understudied proteins, which are members of druggable protein families associated with rare diseases. This NOFO is intended to jumpstart research on these understudied proteins and provide applicants with funding to perform basic biochemical and/or biological work to further characterize them within the context of rare disease. The funding opportunity is sponsored by the Department of Health and Human Services National Institutes of Health, with eligible applicants including tribal organizations, state/local governments, non-profits, higher education institutions, small businesses, and others. The NOFO is assigned to several NIH grant programs, including Mental Health Research Grants, Allergy and Infectious Diseases Research, and Extramural Research Programs in the Neurosciences and Neurological Disorders.