PAR-25-060-Full-Announcement.html

This document is a Funding Opportunity Announcement (FOA) for the Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed) federal grant opportunity.

The FOA encourages the development and validation of animal models and human/animal tissue ex vivo systems that recapitulate the phenotypic and physiologic characteristics of a defined neurological or neuromuscular disorder. The goal is to promote improved translational relevance of animal models or ex vivo systems for future neurotherapeutic development. The FOA is part of the IGNITE program focused on enabling early-stage drug discovery. Eligible applicants include county governments, tribal organizations, state governments, non-profits, small businesses, and higher education institutions. The funding is provided through the National Institute of Neurological Disorders and Stroke (NINDS) under the Department of Health and Human Services.