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This document is a Notice of Funding Opportunity (NOFO) for the NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional) grant program.

The NOFO encourages applications for multi-site exploratory and confirmatory clinical trials focused on promising interventions; biomarker or outcome measure validation studies; and ancillary studies designed to add scientific aims to active studies being conducted within the NIH StrokeNet. Successful applicants will collaborate and conduct the study within the NIH StrokeNet infrastructure. The NIH StrokeNet National Coordinating Center, National Data Management Center, and Regional Coordinating Centers will provide implementation support. Eligible applicants include non-501(c)(3) nonprofits, for-profit organizations, 501(c)(3) nonprofits, and other entity types. The funding opportunity is sponsored by the Department of Health and Human Services National Institutes of Health under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) grant program.

PAR-25-052 Full Announcement Text

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